Gene Information

Name : glnA1 (HMPREF0421_20432)
Accession : YP_003985537.1
Strain : Gardnerella vaginalis ATCC 14019
Genome accession: NC_014644
Putative virulence/resistance : Virulence
Product : glutamate--ammonia ligase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0174
EC number : 6.3.1.2
Position : 522410 - 523894 bp
Length : 1485 bp
Strand : -
Note : COG: COG0174; Pfam: PF03951,PF00120; InterPro: IPR004809

DNA sequence :
ATGCAACAATCTAAACTATTTACTGAGATTTTTACGAAAGGATTGTGCATGACCACTTTACAAACTAAAGAAGATGCCGA
AGCTTTGATTAAGCAAGAAGGCATTGAATACGTATCAGTTCGATTTACCGATTTGATTGGCGTTCAGCAGCATTTTACTG
TGCCTGCAAGCGAGTTCTTAAACAGCGCTTTTACAGATGGGATGGCTTTCGACGGCTCTTCTATGCAAGGATTCCAAGCT
ATTAACGAGTCCGATATGAAGCTGATTCCAGACGTAGACACCGCATACATTGACCCATTCCGCAAGCATAAGACTTTGAA
TGTTGCTTTTTCGATTGTGGATCCTGTAACAGACGAGCCTTATTCTAGGGACCCTCGCCAAGTGGCAATTAAAGCCGAAG
CCTACTTAAAGGCAACTGGCATTGCCGATACCGCAAGCTTTGCTCCAGAAGCCGAGTTCTTCATTTTTGACAAGGTGCGT
TTTGCAAACGACATGCAACGCTCCTTCTACGAGGTGGATTCCAACGAAGCTCCATGGAATTCTGGCATTGATACTGAAGA
TGATGGCAGCAACAACATTGGTTTTAAGAATCGCGTAAAGCACGGCTACTTCCCTGTTCCACCTGTTGATCATAATCAAG
ACTTGCGCGACGACATGGTTTACAACCTTCAAAAGGTTGGCTTGATTCTTGAGCGTTCTCACCATGAGGTTGGCGGCGCA
GGTCAGCAGGAAATCAACTACCGTTACAATACGCTTGTTCATGCTGGCGACGACTTAATGAAATACAAGTACGTTGTTCA
CGAGACTGCTGCTTTGGCTGGTAAGGCTGCAACATTTATGCCTAAGCCAATTGCTGGAGATAACGGCACTGGCATGCACT
GCCATCAGTCGCTTTGGAAGGATGGTAAGCCATTGTTCTATGCGGAAACTGGTTATGCTCAGCTTTCCGATATTGCGCGC
TGGTACATTGGCGGCTTAATTAAGCACGCGTCTTCTGTGCTCGCTTTTACAAATCCTTCACTTAACTCTTACCACCGCCT
TGTTCCAGGATACGAAGCCCCAGTCAACTTGGTTTACTCTGCTCGTAACCGTTCTGCAGCTATTCGTATTCCTCTTGCTG
GAGAGGCTCCTTCTGCTAAGCGCATTGAGTTCCGCGCTCCGGATCCTTCCTGCAATCCATTCTTAGCGTTCTCTGCTCAG
CTTATGGCTGGCTTAGACGGCATTATGAACCACATTGAGCCTCCTGCTCCTGTTGATAAAGATCTCTACGAGCTTCCTCC
AGAAGAGCATGACGGCATTAAGCAAGTTCCTTCTTCACTTGGTGAGGCTTTGCAAGCTTTGGAAGAAGATCACGACTTCC
TTATGCAAGGAGATGTGTTTACTAGCGACTTGATTGAAACTTGGCTTAATCTAAAGCATGAAGAGATGGATATGGCTCGT
TTGGCTCCAACGCCACTCGAGTATGAGCTTTACTTCCATATCTGA

Protein sequence :
MQQSKLFTEIFTKGLCMTTLQTKEDAEALIKQEGIEYVSVRFTDLIGVQQHFTVPASEFLNSAFTDGMAFDGSSMQGFQA
INESDMKLIPDVDTAYIDPFRKHKTLNVAFSIVDPVTDEPYSRDPRQVAIKAEAYLKATGIADTASFAPEAEFFIFDKVR
FANDMQRSFYEVDSNEAPWNSGIDTEDDGSNNIGFKNRVKHGYFPVPPVDHNQDLRDDMVYNLQKVGLILERSHHEVGGA
GQQEINYRYNTLVHAGDDLMKYKYVVHETAALAGKAATFMPKPIAGDNGTGMHCHQSLWKDGKPLFYAETGYAQLSDIAR
WYIGGLIKHASSVLAFTNPSLNSYHRLVPGYEAPVNLVYSARNRSAAIRIPLAGEAPSAKRIEFRAPDPSCNPFLAFSAQ
LMAGLDGIMNHIEPPAPVDKDLYELPPEEHDGIKQVPSSLGEALQALEEDHDFLMQGDVFTSDLIETWLNLKHEEMDMAR
LAPTPLEYELYFHI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
glnA YP_003728749.1 glutamine synthetase Not tested cag PAI Protein 5e-83 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
glnA1 YP_003985537.1 glutamate--ammonia ligase VFG1399 Protein 4e-144 63