Gene Information

Name : thrA (HMPREF0421_20315)
Accession : YP_003985420.1
Strain : Gardnerella vaginalis ATCC 14019
Genome accession: NC_014644
Putative virulence/resistance : Unknown
Product : homoserine dehydrogenase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0460
EC number : 1.1.1.3
Position : 379351 - 380739 bp
Length : 1389 bp
Strand : +
Note : COG: COG0460; Pfam: PF03447,PF00742; InterPro: IPR001342

DNA sequence :
ATGGTTACGGTAAATGCAGAAAATGCAGAAAATAGTGATGGATTGGTTGCTGGCGACTTTTCTGCTGAGCCAATCCGCGT
GGGTCTTTTAGGAGCCGGAACAGTAGGATCGCAAACAGCGCGTCTAATAGTGGAAGAAAACTCTGACTTATCGTCGAGAA
TCGGCGCCCCGCTAGAGCTTGCAGGAGTAGCATGCTTGCATCCAGAAGATGTGGATGCTCCATGGATTGCCAAAAATCTT
CTAAGCGCAGACGCTCTAGCATTATGTGAACGCGAAGATATAGACATAATCGTTGAGCTAATTGGCGGTTTGGAACCAGC
GCACACATTTGTAAAAACCGCTCTAGAATGCGGAAAGTCGGTTGTAACAGCAAACAAAGCATTACTTGCAAAGTTTGGTC
CAGAACTCTACGATTGCGCGCAAAAAAACGGAGTGGATTTAAGTTTCGAGGCGTCTGTTGCAGGTGCAATCCCAATTTTG
CGTCCGCTTAGAGAGTCGCTTGTAGGCGACAAAATCACGCAAATTTTTGGAATCGTAAACGGAACTACAAACTATATTCT
TGACGAGATGACGGTTCGCGGTCTTGATTTTGATTCGGCTTTACGCGCGGCTCAAGAAAAGGGGTACGCGGAGGCGGATC
CTACAGGAGACGTTGAAGGATTTGATGCAGCAAACAAGGCTGCTATTCTTGCAACACTTGCATTCCAAATGCCAATAAGC
ATTGATGACGTCAGCGTTGAAGGAATTAGCGCGATTACGGCTGAAGACATTGCTGCGGCAAGTGCAGAAAATCGCGTGAT
TAAGCTGCTTGCAGCGGTTGCTTGCGATTCGAATGGATTGGTGAGCGCAAGCGTTTACCCAGCGTTGGTTAGCAAAGAGC
ATCCGCTGGCTTCCGTTCATGGCAGCTTTAACGCCGTTTTTGTTAAAGCGCAAGCGGCGGATGATCTTATGTTCTACGGC
CGCGGCGCTGGTGGTGCGCCAACAGCCAGCGCGGTTGTTGGAGATATTGTTGGAGCTGCTAGAAATATAGCGCGCGGTTT
CAGCGATGCCAGCGTGCCAATGTATAACGCAAAATCTTTGGCTTCCACGCGCTCGATTCGTGCGGATTTTGTTGTGCGAT
GCAGCATGGAGGATACTTCACTTGCTCTTTGCAGCGAAGTGATGGATGTGTTTGATGCGCATGGAGCTAACGCGGAACGA
TTGCCTATGCTTTGCCAAACTCAATATGAGGGCGAGGGTGATTGCCCAGCTTGCGGAATCGGCGGTCCTGGTGATTTGCG
TGTGCTTGTAAAAGATTGCACAGAGGCTGATTTGCGCGCAATTCTTGCTGATTTGCAAAAAGTGGATGTTGTGTGTGCAA
AGCCTCTTGCTTTGCGAATTATTGAGTAA

Protein sequence :
MVTVNAENAENSDGLVAGDFSAEPIRVGLLGAGTVGSQTARLIVEENSDLSSRIGAPLELAGVACLHPEDVDAPWIAKNL
LSADALALCEREDIDIIVELIGGLEPAHTFVKTALECGKSVVTANKALLAKFGPELYDCAQKNGVDLSFEASVAGAIPIL
RPLRESLVGDKITQIFGIVNGTTNYILDEMTVRGLDFDSALRAAQEKGYAEADPTGDVEGFDAANKAAILATLAFQMPIS
IDDVSVEGISAITAEDIAAASAENRVIKLLAAVACDSNGLVSASVYPALVSKEHPLASVHGSFNAVFVKAQAADDLMFYG
RGAGGAPTASAVVGDIVGAARNIARGFSDASVPMYNAKSLASTRSIRADFVVRCSMEDTSLALCSEVMDVFDAHGANAER
LPMLCQTQYEGEGDCPACGIGGPGDLRVLVKDCTEADLRAILADLQKVDVVCAKPLALRIIE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00305 YP_008207770.1 Homoserine dehydrogenase Not tested AbaR25 Protein 6e-43 44
BJAB0868_00309 YP_008211635.1 Homoserine dehydrogenase Not tested AbaR26 Protein 6e-43 44