Gene Information

Name : nrdE (HMPREF0421_21332)
Accession : YP_003986437.1
Strain : Gardnerella vaginalis ATCC 14019
Genome accession: NC_014644
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit alpha
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0209
EC number : 1.17.4.1
Position : 1632701 - 1634923 bp
Length : 2223 bp
Strand : +
Note : COG: COG0209; Pfam: PF08343,PF00317,PF02867; InterPro: IPR013346

DNA sequence :
ATGAATAGCACGGATCCGATGAGCGAATCTACTTCGCTTAATCTTGATCACACTGACGACACCAACACTGCTAGCAGCAC
AGCAGAGCGCATTCGCAACAGCCGCGACTACCACGTTCTTAACGCTATGCTCGGTCTTTTCGACCCAGAAAAAGGTATTC
AGTTTGATAAAGATCAGGAAGCAGAAAAGCTTTACGTTTCGGGTTACGTGCAAGAACACAGCATGAAGTTTGCTTCAACT
CATGAGCGCTTGAACTATTTGATTAGCAACTACTACTACAACGGAAACGTGTTCGGCAAGTATAGCAGCGAGTTTCTAGA
TAAGTTCTACGAGCACGCAGAAGCTGCTCACCACACTTTTGGCACTTTCTTGGGTGCTTTTAAGTTCTACACTTCTTACG
CTTTAAAGACTTTCGACGGCAAGCAATATTTGGAAAACTTCGCTCAGCGCGCAGCAGCCGTAGCTTTGGAACTTGCAGAT
GGCGATGAAAAAGCAGCGCTCAACTATTTGGACGAGATGCTTGCAGGCCGCTTCCAGCCAGCCACTCCAACGTTCTTGAA
TCTTGGTAAAGCTCAGCGCGGAGAGGCTGTGAGCTGCTTCCTCGTGCGTTTGGAAGATAATATGGAGTCTATTGCACGCG
GAATTAACTCTGCTTTGCAGCTTTCTAAGCGCGGCGGCGGCGTGGCTCTGCTTCTTACGAATTTGCGCGAGCTTGGTGCT
CCTATTAAGCGCATCGAAAATCAGTCGAGTGGCGTTGTGCCTGTTATGAAGCTTTTGGAAGATTCATTCTCTTATGCTAA
TCAGCTTGGCGCTCGTCAGGGCGCTGGTGCCGTGTATATTAGCGCTCACCACCCAGATATTATGCGTTTCCTTGACACTA
AGCGCGAGAACGCGGACGAGAAGATTCGTATTAAGTCGCTTTCTTTGGGTGTTGTGATTCCAGATATTACTTTTGAGCTT
GCTAAGCGTAAGGAAAAGATGGCTTTGTTTAGCCCTTACGACGTTGAGCGCGAGTACGGAAAGCCTTTTGCAGACATCTC
CGTTACCGAGCATTACGATGAGATGGTTGCAAATCCTCGCATTCACAAGAAGTACATCGACGCTCGCGAATTCTTTATGA
CTCTTGCAGAGATTCAGTTTGAGTCTGGATACCCTTACATTTTGTTTGAAGATACTGTAAATCGCACAAATCCTATTGAA
GGCCGCATTACTATGAGCAACTTGTGCTCCGAGATTTTGCAAACTCAAGAGGCAAGCACTTATAACGCCGACTTGTCTTA
TAGCCACGTTGGTCGCGATATTTCTTGCAATCTTGGCTCGCTTAATATTGCTAAGGCGATGGACGGTGACTTGGGTACAA
GCGTTGATTTGGCTGTGCGCGCGCTCACGTCTGTTTCGGAGCATACTTCGATTGATTCCGTGCCTTCGATTCGTCGCGGA
AACGCGGAAGGCCATGCTATTGGCTTGGGTCAAATGAATTTGCACGGTTTCCTTGCTCGCGAGCACATGCAGTACGGAAG
CGAGGAAGCTCTTGACTTTACAGACATGTACTTTATGACGGTTGCTTACCACGCTTATAAGGCTTCTCACGCTTTGGCTG
TAGAGCGCGGGACTGCTTTTGCAAGCTTTAAGACTAGCGCTTACGCTAAGCCTGCAGGAAAAGGCAACTACTTCGATAAG
TACACTGATGGCAGCCGCTCGCTTGAGCCTAAAACTCAAAAGGTTCGCGATTTGTTTGCTCGTTTTAACGTTGCAATTCC
AACCGTTTCGGATTGGGAGCAATTGCGCGACGAGATTTTGCGCGATGGCATTTACAACGAGTATTTGCAGGCTGTTCCTC
CAACTGGTTCCATATCGTACATAAACCATTCCACGAGTTCAATACACCCGATTGCTTCTCGCATTGAGATTCGCAAAGAG
GGCAAAGTTGGCCGCGTCTACTACCCTGCTGCATACATGACGAATGACAATATGCAGTACTTTAAGGATGCTTACGAGAT
TGGTTGGAAGGCAATTATTGACACTTACGCGGAGGCAACTCAGCATGTAGATCAGGGATTGTCTCTTACTTTGTTCTTCC
CAGACACTACGACTACTCGCGATTTGAACAAAGCTCAGATTTACGCGTGGCGTAAGGGTATTAAGACTCTTTACTACATT
CGTATTCGCCAGAAGGCTTTGGAAGGTACAGAAATCGAGGGTTGCGTAAGCTGCACGCTGTAA

Protein sequence :
MNSTDPMSESTSLNLDHTDDTNTASSTAERIRNSRDYHVLNAMLGLFDPEKGIQFDKDQEAEKLYVSGYVQEHSMKFAST
HERLNYLISNYYYNGNVFGKYSSEFLDKFYEHAEAAHHTFGTFLGAFKFYTSYALKTFDGKQYLENFAQRAAAVALELAD
GDEKAALNYLDEMLAGRFQPATPTFLNLGKAQRGEAVSCFLVRLEDNMESIARGINSALQLSKRGGGVALLLTNLRELGA
PIKRIENQSSGVVPVMKLLEDSFSYANQLGARQGAGAVYISAHHPDIMRFLDTKRENADEKIRIKSLSLGVVIPDITFEL
AKRKEKMALFSPYDVEREYGKPFADISVTEHYDEMVANPRIHKKYIDAREFFMTLAEIQFESGYPYILFEDTVNRTNPIE
GRITMSNLCSEILQTQEASTYNADLSYSHVGRDISCNLGSLNIAKAMDGDLGTSVDLAVRALTSVSEHTSIDSVPSIRRG
NAEGHAIGLGQMNLHGFLAREHMQYGSEEALDFTDMYFMTVAYHAYKASHALAVERGTAFASFKTSAYAKPAGKGNYFDK
YTDGSRSLEPKTQKVRDLFARFNVAIPTVSDWEQLRDEILRDGIYNEYLQAVPPTGSISYINHSTSSIHPIASRIEIRKE
GKVGRVYYPAAYMTNDNMQYFKDAYEIGWKAIIDTYAEATQHVDQGLSLTLFFPDTTTTRDLNKAQIYAWRKGIKTLYYI
RIRQKALEGTEIEGCVSCTL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1481 YP_001800875.1 ribonucleotide-diphosphate reductase subunit alpha Not tested Not named Protein 0.0 66