Gene Information

Name : sitA (HMPREF0733_10736)
Accession : YP_003983628.1
Strain : Rothia dentocariosa ATCC 17931
Genome accession: NC_014643
Putative virulence/resistance : Virulence
Product : iron ABC transporter
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG0803
EC number : -
Position : 793709 - 794683 bp
Length : 975 bp
Strand : -
Note : COG: COG0803; Pfam: PF01297; InterPro: IPR006127

DNA sequence : 
ATGACAACCGTATTCACTGCGCACCGTCACGGTGCGAACGCTAACACTGTAAGTACCGCACATCCGCGCCGTTTTCTCAT
GCTGGGGATAGCTCTGGCCAGTATCCTTGTGCTTCTGCTCAGCGCCTGCACTTCGGCGGGGAAGCAAGACGAAAAGAAGA
CTGTGCTCACCACCTTCACCGTGCTGGCGGACATCGCTAAAAACGTTGCGGGTGATCACCTGAATGTCGAATCGCTGACC
AAGCCCGGCACCGAGATTCACGAGTATGAACCTACTCCCAGCGATATTAAGAAGGCGCATGATGCTGATTTGGTGCTCGA
CAACGGGCTGAACCTGGAAAGCTGGTTTACCAAGTTTGTGCAGGATTCTAACGCCCCGCACGCCACCGTGAGCGAGGGGG
TACAGCCGATCAATATTGCCGAGGACGCTTATGCAGGCAAACCCAACCCGCATTCGTGGATGAGCCCCAAGAACGTGCAG
ATTTACGTGGATAATATGGTGCGCGAATTCAGTAAGCTTGACCCCGCCCATGCCGATGATTACCGCACCAATGGGGAAAA
CTATAAGAAACAGCTGCAGCAGGTTCAGGATGAGCTGGTGCGCGATGTTAGCGTTCTGCCCGAGAATCAGCGGGCGCTCG
TAACCTGCGAAGGTGCTTTCTCGTACTTGGCGGCGGATGCCAGTCTCAAGGAAAAATACATTTGGGCGGTGAACTCTGAA
CAGCAGGCAACCCCCTCGCAGCTAAGCTCGACCATTGATTTTGTGCGCGAGAACCAGGTGCCCGCCGTATTCTGTGAGTC
TACCGTCTCGGATGACCCCATGCGCCAGGTCGTGGATGCGACCGGTGCCAAATTCGGCGGCGTGCTTTATGTAGATTCCC
TCTCTGAGGCGAATGGTCCAGTCCCTACCTATCTTGATATGATTCGTCACGATGCGCGCACCATTGTTGCGGGGCTGACG
GGTAAGCAATCTTAG

Protein sequence : 
MTTVFTAHRHGANANTVSTAHPRRFLMLGIALASILVLLLSACTSAGKQDEKKTVLTTFTVLADIAKNVAGDHLNVESLT
KPGTEIHEYEPTPSDIKKAHDADLVLDNGLNLESWFTKFVQDSNAPHATVSEGVQPINIAEDAYAGKPNPHSWMSPKNVQ
IYVDNMVREFSKLDPAHADDYRTNGENYKKQLQQVQDELVRDVSVLPENQRALVTCEGAFSYLAADASLKEKYIWAVNSE
QQATPSQLSSTIDFVRENQVPAVFCESTVSDDPMRQVVDATGAKFGGVLYVDSLSEANGPVPTYLDMIRHDARTIVAGLT
GKQS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
sitA NP_457255.1 Iron transport protein, periplasmic-binding protein Virulence SPI-1 Protein 8e-75 56
sitA NP_806464.1 iron transporter periplasmic-binding protein Virulence SPI-1 Protein 8e-75 56
sitA NP_461782.1 periplasmic binding protein Virulence SPI-1 Protein 8e-75 56
sitA AAD41065.1 SitA Virulence centisome 63 pathogenicity island Protein 6e-75 56
sitA YP_217781.1 iron transporter: fur regulated Virulence SPI-1 Protein 9e-75 56

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
sitA YP_003983628.1 iron ABC transporter BAC0349 Protein 4e-75 56
sitA YP_003983628.1 iron ABC transporter BAC0439 Protein 3e-67 52

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
sitA YP_003983628.1 iron ABC transporter VFG0525 Protein 3e-75 56