Gene Information

Name : HMPREF0733_10734 (HMPREF0733_10734)
Accession : YP_003983626.1
Strain : Rothia dentocariosa ATCC 17931
Genome accession: NC_014643
Putative virulence/resistance : Virulence
Product : iron (Fe3+) ABC transporter membrane protein YfeC
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG1108
EC number : -
Position : 791930 - 792799 bp
Length : 870 bp
Strand : -
Note : COG: COG1108; Pfam: PF00950; InterPro: IPR001626

DNA sequence : 
ATGAGCATTCTGGATTACCTGGTGGAACCGTTCACCCTTCCCTTCATGACGCGCGCCATGGTTGTTACCGTGATCGCCGC
CGTGGTCTGCGCGCTGCTTTCCTGCTGGCTCGTGATGCTCGGCTGGTCGCTCATGGGCGATGCGATCTCGCACGCGGTAC
TGCCCGGCGTAGTGCTCGCCTATATTGCGGGCATCCCCTTTGCCGTGGGGGCGGTGATCGCTGCACTCGTGGCCGTCACC
CTGATCGGCGCGGTACAGCGCAGCGGGCGCGTGCGCGAGGACGCCGCTATCGGCATTGTCTTCACAACTCTTTTCGCGCT
CGGGCTCGTACTGGTTTCGGTGACGCCCTCAAGCACCGACCTGAACCATATTCTTTTCGGGAACGTGCTGGGCGTATCCT
GGCCCGATGTCTGGCAGGTAGCTATTCTCGCCGTCATCGTGGCGGGTGTCCTGCTGATTAAACGCCGCGATTTTATTCTG
TACGCCTTCGACCGCGGGTTCGCGCACGCTATCGGGCTGCGCCCCAGGGTTCTTGGTGCGCTGCTTCTGGTGATGCTGGC
GCTCACGAGCGTGGTGGCGCTGCAGATCGTGGGAGTTGTGCTCGTAGTCGCCATGCTTGTGATTCCTGGATCGACCGCGC
GTCTGCTCACCGACCGTTTCACGCCAATGCTCGCGGTCTCGGTCGGGGTCTCAACGCTGGGTACACTCGTGGGGCTTTAT
AGTAGCTACCACCTGGATATTTCCCCCGGCGGTGCCGTGGTCGTTACCCAAGGCATTATTTTCTTGGCCGTGTATATATT
CGCCCCGCGCTACGGAATTCTGGGGCGGATACGCGCGGCACGCCGCCCGGCAGAACCGGTAGAAGCCTAG

Protein sequence : 
MSILDYLVEPFTLPFMTRAMVVTVIAAVVCALLSCWLVMLGWSLMGDAISHAVLPGVVLAYIAGIPFAVGAVIAALVAVT
LIGAVQRSGRVREDAAIGIVFTTLFALGLVLVSVTPSSTDLNHILFGNVLGVSWPDVWQVAILAVIVAGVLLIKRRDFIL
YAFDRGFAHAIGLRPRVLGALLLVMLALTSVVALQIVGVVLVVAMLVIPGSTARLLTDRFTPMLAVSVGVSTLGTLVGLY
SSYHLDISPGGAVVVTQGIIFLAVYIFAPRYGILGRIRAARRPAEPVEA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
sitD AAD41068.1 SitD Virulence centisome 63 pathogenicity island Protein 3e-35 46
sitD NP_461785.1 permease Virulence SPI-1 Protein 4e-35 46
sitD YP_217784.1 iron transporter: fur regulated Virulence SPI-1 Protein 1e-35 46
sitD NP_457258.1 Iron transport protein, inner membrane component Virulence SPI-1 Protein 1e-35 46
sitD NP_806467.1 iron transporter inner membrane protein Virulence SPI-1 Protein 1e-35 46
sitC AAD41067.1 SitC Virulence centisome 63 pathogenicity island Protein 2e-32 41
sitC YP_217783.1 iron transporter: fur regulated Virulence SPI-1 Protein 2e-32 41
sitC NP_461784.1 permease Virulence SPI-1 Protein 2e-32 41
sitC NP_457257.1 Iron transport protein, inner membrane component Virulence SPI-1 Protein 2e-32 41
sitC NP_806466.1 iron transporter inner membrane protein Virulence SPI-1 Protein 2e-32 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
HMPREF0733_10734 YP_003983626.1 iron (Fe3+) ABC transporter membrane protein YfeC BAC0352 Protein 2e-35 46
HMPREF0733_10734 YP_003983626.1 iron (Fe3+) ABC transporter membrane protein YfeC BAC0442 Protein 2e-35 46
HMPREF0733_10734 YP_003983626.1 iron (Fe3+) ABC transporter membrane protein YfeC BAC0441 Protein 2e-31 43
HMPREF0733_10734 YP_003983626.1 iron (Fe3+) ABC transporter membrane protein YfeC BAC0351 Protein 1e-32 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
HMPREF0733_10734 YP_003983626.1 iron (Fe3+) ABC transporter membrane protein YfeC VFG0528 Protein 2e-35 46
HMPREF0733_10734 YP_003983626.1 iron (Fe3+) ABC transporter membrane protein YfeC VFG0527 Protein 1e-32 41