Gene Information

Name : clpB (HMPREF0733_10529)
Accession : YP_003983421.1
Strain : Rothia dentocariosa ATCC 17931
Genome accession: NC_014643
Putative virulence/resistance : Virulence
Product : chaperone protein ClpB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 583531 - 586128 bp
Length : 2598 bp
Strand : -
Note : COG: COG0542; Pfam: PF02861,PF00004,PF07724; InterPro: IPR003959

DNA sequence :
ATGGACGCAAAATTCACAACCAAGAGCCAAGAAGCGCTCTCCGCCGCTAATATGAACGCGCAGACAGCGGGTAATCCCAG
CATCGAACCTGCGCACATCCTCAAAGCACTGATGGATCAACGAGAAGGCGTTGCCGTAGCGGTTCTCAAGGCCGCAGGAC
TCGACATTGATGCCATTTCGGAAGCCGCATCCGCAGAGATTAAGAAGCTGCCGAAGGCATCTGGCGCATCGGTGCAGAAC
GCAAACTTCAGCCGCAGCGCCCTTGCCGCTATTCAGAGTGCGCAGACCCACGCTCAGAAATTCGGCGACACCTACATCTC
CACCGAAATGCTGCTGCTGGGTATCGCAAGCGGCGATAGCGATACCGCTCGCGCACTTGAAAACCTGGGCGCAACTGCCA
AAGTTATCGAAGAGACCATTCCCCAAGTACGAGGAGACCGCACCGTGGATACCCCGGACCCCGAAGGCACCTTCCAGGCC
CTTGAAAAGTACGGTACCGACCTGACCGCGCTCGCCCGCGAAGGCAAGCTCGACCCCGTGATCGGCCGAGACTCCGAAAT
CCGCCGCGTGGTGCAGGTGCTCTCACGGCGCACCAAGAACAACCCCGTGCTCATTGGTGAACCCGGCGTCGGTAAAACCG
CCGTGGTCGAAGGGTTGGCTCAGCGCATGGTCTCTGGCGACGTCCCCGAATCCCTGCGCGGTAAAACCCTGATCAGCCTT
GACCTTGGGTCCATGGTTGCGGGCGCTAAATACCGCGGCGAATTCGAGGAACGCCTCAAGGCCGTGCTCGAAGAAATTAA
GAAATCCGAAGGTCAGATCGTCACCTTTATCGATGAGATGCATACCGTGGTTGGTGCGGGTGCATCCGAAGGTTCCATGG
ATGCGGGCAATATGCTCAAGCCCATGCTGGCGCGCGGCGAGCTGCGCATGATTGGCGCTACCACGCTCGACGAGTTCCGC
GAGAACATTGAGAAAGACCCCGCTCTGGAACGTCGTTTCCAGCAGGTGTACGTGGGTGAGCCTAGTGTTGATGACACCAT
CGGTATTCTGCGTGGGCTCAAGGAACGCTACGAGGCGCACCATAAGGTGCAAATCTCAGATGCCGCTCTAGTCGCCGCCG
CAGCTCTTTCAAATAGGTACATTCCCTCACGTCAGCTGCCCGATAAGGCGATCGACCTGGTGGATGAGGCCGCATCGCGC
CTGCGCATGGAGATCGACTCGGCTCCCGAGGAAATCGACCAGCTGCGCCGCGCCGTAGACCGTCTGACTATGGAAGAACT
GGCCCTCAAGAACGAGACCGACCCGGCGTCGAAGGAACGCTTGGCGGCGCTGCGCAAAGACATGGCTGATAAGAAAGAAC
AGCTGGATGCGCTCAACGCCCGCTGGGAAGCCGAAAAGGCCGGTCTGAACCGCGTGGGCGATCTCAAGAGCGAAATCGAC
GAGCTGCGCTCGCGTGCCGAGGTAGCACAGCGTGAGGGTAACCTGGCGGATGCATCCCGCCTGCTCTACGGCGAAATTCC
CGCCAAGGAGAAGGAACTGGAAGAAGCTCAGCGCGCCGAAACTGAGGCTCATGGCGAGGCTATGGTCTCTGAAGAGGTCA
CGGCTGACGACATTGCCGAGGTTATCTCTTCCTGGACGGGCATTCCCGCCGGGCGCATGCTTCAGGGCGAATCCGAGAAG
CTGCTGGAGATGGAGAAGCGCATCGGTGAACGCCTGATCGGTCAGGAAGCCGCCGTGGTTGCTGTGGCGGATGCGGTTCG
CCGCGCCCGCGCCGGAATTTCCGACCCGAACCGCCCGATTGGTTCCTTCCTGTTCCTGGGACCGACCGGTGTGGGTAAGA
CCGAACTTGCGAAGGCTCTGGCGGAGTTCCAGTTTGACGACGAGCACGCCCTAGTGCGCATCGACATGAGTGAGTACGGC
GAGAAGCACAGCGTTTCCCGCCTGGTGGGTGCGCCTCCCGGATATGTGGGGCATGAAGAAGGCGGTCAGCTGACCGAGGC
TGTGCGCCGTCGCCCCTACTCCGTGGTGCTGCTGGACGAGGTTGAGAAGGCCCACCCCGAGGTCTTCGATATTCTGCTGC
AGGTGCTCGATGACGGTCGTCTGACCGACGGTCAGGGCCGCACCGTGGACTTCCGCAACGTGATTCTGATTCTGACCTCG
AACCTGGGTTCCCAGTATCTGGTCGATCAGGAGATGCCGTTTGAGGAGCGTACCGAGAAGGCGATGCAGGTGGTTCACCA
GGCGTTCCGTCCCGAGTTCCTGAACCGTCTGGATGACATCATCATGTTTGAGCCGCTCTCTTCCGAGCATCTGGGGCAGA
TTGTGAACCTGCAGATTCAGGGCATGGGCAAGCGTCTGACCGACCGCCGCCTGACCCTGGATGTTACCCCCGCCGCCCTG
GAGTGGCTGGGCTTGGCAGGGTACGATCCGGCCTTCGGTGCCCGCCCGCTGCGCCGCCTGGTACAGCGCGAGATCGGCGA
CCGTCTGGCGAAGGGCATCCTCTCGGGCGCTATCCACGATGGCGACACCGTAGAGGTGGATGTGAACCCGGATGTTGCAA
TGGACGGTCTGTCAGTGACCTCCAAGCGTGACGACTAA

Protein sequence :
MDAKFTTKSQEALSAANMNAQTAGNPSIEPAHILKALMDQREGVAVAVLKAAGLDIDAISEAASAEIKKLPKASGASVQN
ANFSRSALAAIQSAQTHAQKFGDTYISTEMLLLGIASGDSDTARALENLGATAKVIEETIPQVRGDRTVDTPDPEGTFQA
LEKYGTDLTALAREGKLDPVIGRDSEIRRVVQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQRMVSGDVPESLRGKTLISL
DLGSMVAGAKYRGEFEERLKAVLEEIKKSEGQIVTFIDEMHTVVGAGASEGSMDAGNMLKPMLARGELRMIGATTLDEFR
ENIEKDPALERRFQQVYVGEPSVDDTIGILRGLKERYEAHHKVQISDAALVAAAALSNRYIPSRQLPDKAIDLVDEAASR
LRMEIDSAPEEIDQLRRAVDRLTMEELALKNETDPASKERLAALRKDMADKKEQLDALNARWEAEKAGLNRVGDLKSEID
ELRSRAEVAQREGNLADASRLLYGEIPAKEKELEEAQRAETEAHGEAMVSEEVTADDIAEVISSWTGIPAGRMLQGESEK
LLEMEKRIGERLIGQEAAVVAVADAVRRARAGISDPNRPIGSFLFLGPTGVGKTELAKALAEFQFDDEHALVRIDMSEYG
EKHSVSRLVGAPPGYVGHEEGGQLTEAVRRRPYSVVLLDEVEKAHPEVFDILLQVLDDGRLTDGQGRTVDFRNVILILTS
NLGSQYLVDQEMPFEERTEKAMQVVHQAFRPEFLNRLDDIIMFEPLSSEHLGQIVNLQIQGMGKRLTDRRLTLDVTPAAL
EWLGLAGYDPAFGARPLRRLVQREIGDRLAKGILSGAIHDGDTVEVDVNPDVAMDGLSVTSKRDD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 1e-106 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpB YP_003983421.1 chaperone protein ClpB VFG2076 Protein 3e-116 45
clpB YP_003983421.1 chaperone protein ClpB VFG2084 Protein 3e-112 44