Gene Information

Name : HMPREF0733_12166 (HMPREF0733_12166)
Accession : YP_003985057.1
Strain : Rothia dentocariosa ATCC 17931
Genome accession: NC_014643
Putative virulence/resistance : Virulence
Product : ABC transporter ATP-binding protein
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG1120
EC number : 3.6.3.28
Position : 2442819 - 2443670 bp
Length : 852 bp
Strand : -
Note : COG: COG1120; Pfam: PF00005; InterPro: IPR003439

DNA sequence : 
GTGAAGGCTTGTGCAGAGATTAGCGAAAGCCGACTCGCAGGCGAAGACATGGTCGTAGCCTATGGCGACCACACAGTGCT
CAGCGGTATAGACTTCAAGGTGCTTGAGGGTGAGCTTACCGTTATTTTGGGTCCTAACGCCTGCGGTAAATCTACCTTAC
TCAAAGCTCTGGCGCGTGTGAATCCTCTCAAAGGCGGAAAGGTCTTTCTTGATGGTCTGCCGCTTTCAAAGATGAAATCC
CGCTCCATCGCGCAGATTCTCGCCATGCTTCCTCAAACGCCGGAGGCACCCACCGGGTTGACCGTGGCGGATGTTGTGGC
ACGCGGCCGGTACCCGCATCAATCCCTTCTGCGTTCCTGGTCTGAGAAAGATGAGGCGGCCTGCGTTGAGGCTATGGAAG
CCGCGAACGTGTTGGAACTGGCCGAACGTCCTATTGAGGCGCTTTCCGGCGGTCAGCGTCAGCGCGTGTGGATTGCCATG
ACCCTTGCCCAGCAGACGCCTTTGATTCTGTTGGACGAGCCAACCACCTACCTGGATATTACCCACCAGATTGAGGTGCT
AAACCTTACCAAGAAGCTCCACTCTGAGGGGCATACCGTTGCGGTTGTGCTACACGATCTGAACCTAGCTTTCCGATACG
CCACTCATGCGGTGCTCATGAAGGAAGGTAGGATTATCGCTCAGGGTGATCCTCAGGAAATTGTCACTGCCGAGCTAATT
CAGGAAGTTTTCGACCTAGAATCTGTTATATGCGATGACCCCTGTACCGGAACACCACTGGTAGTTCCGGCAGCTCACCA
AGAGATTACTACTGCCGCGGACGCAATTGCCGCCGCCCGCGAAGGTCACTAA

Protein sequence : 
MKACAEISESRLAGEDMVVAYGDHTVLSGIDFKVLEGELTVILGPNACGKSTLLKALARVNPLKGGKVFLDGLPLSKMKS
RSIAQILAMLPQTPEAPTGLTVADVVARGRYPHQSLLRSWSEKDEAACVEAMEAANVLELAERPIEALSGGQRQRVWIAM
TLAQQTPLILLDEPTTYLDITHQIEVLNLTKKLHSEGHTVAVVLHDLNLAFRYATHAVLMKEGRIIAQGDPQEIVTAELI
QEVFDLESVICDDPCTGTPLVVPAAHQEITTAADAIAAAREGH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
iusE YP_005143742.1 iron ABC transporter ATP-binding protein Virulence Not named Protein 9e-63 51
fagC YP_005682397.1 ATP binding cytoplasmic membrane protein Virulence PiCp 1 Protein 5e-55 47
fagC YP_005684488.1 ATP binding cytoplasmic membrane protein Not tested PiCp 1 Protein 5e-55 47
fagC YP_005680307.1 ATP binding cytoplasmic membrane protein Not tested PiCp 1 Protein 5e-55 47
fagC YP_003782430.1 ABC transporter ATP-binding protein Not tested PiCp 1 Protein 5e-55 47
fecE AAL08451.1 ATP-binding protein FecE Virulence SRL Protein 7e-48 44
SPN23F_09560 YP_002510939.1 ferric siderophore ABC transporter ATP-binding protein Virulence PPI-1 Protein 1e-51 43
SP_1035 NP_345510.1 iron-compound ABC transporter ATP-binding protein Not tested PPI-1 Protein 1e-51 43
ciuD YP_005681255.1 Iron ABC transporter ATP-binding protein Virulence PiCp 4 Protein 7e-45 41
ciuD YP_005683346.1 Iron ABC transporter ATP-binding protein Virulence PiCp 4 Protein 7e-45 41
ciuD YP_003783391.1 iron ABC transporter ATP-binding protein Virulence PiCp 4 Protein 7e-45 41
ciuD YP_005685432.1 Iron ABC transporter ATP-binding protein Virulence PiCp 4 Protein 7e-45 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
HMPREF0733_12166 YP_003985057.1 ABC transporter ATP-binding protein BAC0164 Protein 5e-48 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
HMPREF0733_12166 YP_003985057.1 ABC transporter ATP-binding protein VFG0925 Protein 2e-62 51
HMPREF0733_12166 YP_003985057.1 ABC transporter ATP-binding protein VFG1042 Protein 4e-48 44