Gene Information

Name : leuS (HMPREF0733_11977)
Accession : YP_003984868.1
Strain : Rothia dentocariosa ATCC 17931
Genome accession: NC_014643
Putative virulence/resistance : Unknown
Product : leucine--tRNA ligase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 2207644 - 2210139 bp
Length : 2496 bp
Strand : -
Note : COG: COG0495; Pfam: PF00133,PF08264; InterPro: IPR002302

DNA sequence :
GTGTCTGCTGAGGTAGAGACCGAACGCACTGAGAATGCGTATGACTTCCGTGCACAGGAAGCGAAATGGCGCCCCTACTG
GGAAGAAACGGGTGTCTTCAAGCCAACCGGCAACGCCGCGAAAGGTCGCCGCTATGTGCTAGACATGTTTCCGTACCCCT
CAGGTGACCTGCATATGGGCCACGCAGAAGCGTTTGCTATTGGAGACATGAATGCCCGCTACTACAAGCAGTGCGGCTAC
GATGTTCTGCACCCCATCGGCTGGGATTCCTTCGGTTTGCCCGCAGAAAACGCTGCTATCAAGAACGGTACCCACCCAAA
AGAGTGGACCTACAAGAATATTGACACGCAGGCAGAATCTTTCAAACGTTACGCTATCGCCGTGGATTGGGATCGACGTC
TGCACACCTCAGACCCCGAATACTATAAGTGGACCCAGTGGCTTTTCGAGCAGTTCTATAAGCAGGGCCTGGCCTACCGC
AAAGACTCAATGGTGAACTGGTGCCCCAAAGATCAGACCGTGCTCGCGAACGAACAGGTGGTTAATGGCGCTTGCGAACG
ATGCGGCACCACGGTTACTAAGAAGTCGCTGAATCAGTGGTACTTCAAGATTACTGACTACGCCCAGCAGCTTCTTGACG
ATATGGAGCAGCTTGAGGGCAAATGGCCCGAACGTGTTCTGCTGATGCAGCGGAACTGGATTGGGCGTTCCGAAGGTGCT
GAGGTTCGCTTCGAGATTGAGGCTACCGAGGCGCAGCCTGCCGAATCCTTCACAGTCTTCACCACCCGCCCAGATACCCT
CTACGGTTCAACCTTTATTGTTGTTGCCGCTGACTCGACCTTTGCCGAGCAGATTGTGGCACCCGATCAGGCACAGGCGC
TAGAGGACTACCGCGAGCAGATTAAGGCCCTCAGCGATATTGACCGCCAGTCTTCCGAGCGTGAAAAGACCGGTATGTTT
ACTGGGCGTTACGCAATCAACCCGCTGAACGGCGCAAAGTTGCCGGTGTGGGCTTCAGATTATGTGCTTGCCGATTATGG
TACCGGCGCTATTATGGCGGTGCCCGCGCACGATCAGCGTGACCTTGACTTCGCCAAGAAATTCGACCTGCCGATCGTGA
CGGTGCTCGATGTTGAGGGCGAGGAAGACCCTGCCGAGTCGGGTATCGCCACTGCGGGCGATGGGGTACTCATTAACTCC
GGTGAGCTAACCGGACTTCCTAAGGCAGAGGCTATTGCGAAGGCTACCGAGCTGGTTGAGGCTGCCGGCACCGGCGAAGG
TAAGGTTATTTACCGCCTGCGCGACTGGTTGCTCTCGCGCCAGCGTTTCTGGGGCACGCCTATTCCCGTGATTCACTGTG
AGGACTGCGGCGAGGTACTGGTTCCTGAAGAACAGCTGCCGGTTCTGCTCCCAGATAATCTGCGCGGTGAACAGTTAGCT
CCCAAGGGACAATCGCCCCTTGCTGCCGCCGATGACTGGGCCATAGTTCCCTGCCCGCAATGCGGTAAGAGCGCTCGCCG
CGATTCCGACACTATGGATACCTTCGTGGATTCTTCCTGGTACTTCCTGCGCTATGTTTCACCCCGTTATGCCGAAGGCC
CCTTCGACCCGCAGGCGATCAGGGAATGGGGCGCGGTCGATATGTACGTGGGCGGTGTGGAACATGCGATTCTGCACCTG
CTGTATGCGCGTTTCTTCACGAAAGTTATTCGTGATTTGGGACTGATTGAGCACGGCGAGCCGTTCAAAGCTCTCATGAA
TCAGGGGCAGGTTCTCAACGGCGGTAAGGCTATGTCGAAGTCGCTCGGCAACGGCGTAAACCTGGGTGAGCAACTTGATA
CGTTCGGTGTGGATGCGGTGCGCACCACCATGATCTTCGCTTCGCCGCCCGAAGATGATGTGGACTGGGCGGACGTTTCA
CCCGCCGGTTCGCAGAAGTTCTTGGCGCGCGCATGGCGTGTTGCTCAGGACGTTACCTCCGAACCTGGCGTGGATGCGGC
ATCCGGCGATGCGAACCTGCACAAGCTGGTGGCGCGTACCGTACACGATGTGAAGCAGCTTCTTGACTCGGGTAAGTTCA
ACGTGGTGGTCGCCAAGACTATGGAGCTGGTGAACGCTACCCGTAAGGCTGTCGATTCGGGCTCTGGGGGAGCGGACCCT
GCGGTGCGTGAAGCCACCGAAACTATTGCGATCTTGTTGTCACTCTACGCGCCGTACACCGCCGAAGACATGTGGCACGC
GCTGGGACACGATAACCCGGTGCTGACCGCAGGTTTCCCGCAGGTAGATGAATCCCTGCTCGTGGATGATACCGTCACCG
CAATCGTGCAGATCAAGGGCAAAGTGAAGGCGCGCCTTGAGGTATCAAAGGATATTTCTGAAGCTGAGCTTGAAAAACAA
GCCCTGGAGGATGAGACTATCGCGAAGCTGGTGGAAGGCTCCGAAATCCGTAGGGTGATTGTGCGAGCCCCCAAACTGGT
GAATATCGTCATCTAG

Protein sequence :
MSAEVETERTENAYDFRAQEAKWRPYWEETGVFKPTGNAAKGRRYVLDMFPYPSGDLHMGHAEAFAIGDMNARYYKQCGY
DVLHPIGWDSFGLPAENAAIKNGTHPKEWTYKNIDTQAESFKRYAIAVDWDRRLHTSDPEYYKWTQWLFEQFYKQGLAYR
KDSMVNWCPKDQTVLANEQVVNGACERCGTTVTKKSLNQWYFKITDYAQQLLDDMEQLEGKWPERVLLMQRNWIGRSEGA
EVRFEIEATEAQPAESFTVFTTRPDTLYGSTFIVVAADSTFAEQIVAPDQAQALEDYREQIKALSDIDRQSSEREKTGMF
TGRYAINPLNGAKLPVWASDYVLADYGTGAIMAVPAHDQRDLDFAKKFDLPIVTVLDVEGEEDPAESGIATAGDGVLINS
GELTGLPKAEAIAKATELVEAAGTGEGKVIYRLRDWLLSRQRFWGTPIPVIHCEDCGEVLVPEEQLPVLLPDNLRGEQLA
PKGQSPLAAADDWAIVPCPQCGKSARRDSDTMDTFVDSSWYFLRYVSPRYAEGPFDPQAIREWGAVDMYVGGVEHAILHL
LYARFFTKVIRDLGLIEHGEPFKALMNQGQVLNGGKAMSKSLGNGVNLGEQLDTFGVDAVRTTMIFASPPEDDVDWADVS
PAGSQKFLARAWRVAQDVTSEPGVDAASGDANLHKLVARTVHDVKQLLDSGKFNVVVAKTMELVNATRKAVDSGSGGADP
AVREATETIAILLSLYAPYTAEDMWHALGHDNPVLTAGFPQVDESLLVDDTVTAIVQIKGKVKARLEVSKDISEAELEKQ
ALEDETIAKLVEGSEIRRVIVRAPKLVNIVI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 4e-160 43