Gene Information

Name : tktA (HMPREF0733_11886)
Accession : YP_003984777.1
Strain : Rothia dentocariosa ATCC 17931
Genome accession: NC_014643
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 2102898 - 2105039 bp
Length : 2142 bp
Strand : -
Note : COG: COG0021; Pfam: PF00456,PF02779,PF02780; InterPro: IPR005478

DNA sequence :
ATGACGTACCACCAAGCGAAGGGACAATACGTGACTAACCCTAACGAAAAGTTCGAATGGACTGAGGTAGACCAGCGTGC
GGTTGATACTGCTCGCTTATTGGCAGCCGATGCGGTTGAGAAAGTAGGGTCAGGTCACCCCGGCACCGCCATGAGCCTTG
CTCCTGTTGCCTATCTACTCTTCCAAAAGGTCATGAACCAAGACCCCAATGATGACCGTTGGGAAGGTCGCGACCGTTTC
ATCCTCTCCCCCGGCCACACATCGCTGACTCTTTACACCCAATTATTTATGGGTGGGTATGGTCTTGAGATGGAGGATCT
AGAATCTCTTCGCACATGGGATGCGCTCACTCCTGGACATCCTGAATATAAGCACACCAAGGGTGTAGAAATTACGACTG
GTCCATTGGGTCAGGGGCTCGCTTCTGCCGTTGGTTTTGCATATGCTCAACGTTATATGCGTGGTCTTTTCGACCCCGAA
TCCCCGGTTGGTGCTTCTCCCTTTGACCATTATGTGTACTGTATCGCCTCTGAAGGCGATGTTCAGGAAGGCGTAACGGC
AGAAGCCAGTGCGCTTGCTGGGCACCAAGAATTGGGCAATCTCATCGTACTCTGGGATCGCAACCATATTTCTATTGAAG
AAGACACTGACGTTGCATTCACCGAAGACGTGCCAGCTCGTTACCGGGCCTACGGCTGGGATGTTCAGCACGTGGACTGG
ACCAAGACCGGAAACTACGTTGAAGATGTGCAGGAACTCTACAACGCTATTGAGCGCGCGAAAACGGTCACGGATAAGCC
TTCATTCATTGAGGTGCGTACTATCATTGGTTACCCAGCACCCAACAAGCAAAATACTGGGTCCGTTCACGGCTCAAAGC
TGGGGGCCGAAGAAATCGTTGAAACCAAGAAAGTTCTAGGATTTGACCCCGAAAAGAGCTTCTTCATTGAGGATGAGGTT
CTGGCGCATACTCGTGAACTTCGTGAACGCGGGGCTGCTGCGCATAAGGTCTGGAATGAAAAATTTGAGGCATGGGCTCA
GGCTAACCCTGAGCGGGCAAAGCTGTACAACCGCCTGGTGTCAGGCGAAATGCCAGTTGATTATAAGGCTGCTTTCCCTG
TCTTTGAGCCGGGTACTTCACTAGCAACCCGCGCAGCATCCGGCAAAGTCATTAATGCTATTGCTGATACTTTCCCTGAG
CTTTGGGGTGGATCTGCCGATCTAGCAGGTTCTAACCTCACCACCATCAACAACGCCGAATCATTCAACCCGGTTTCGCA
CAGTACGGAGGATTGGACCGGCAACCCCTACGGTCGTGTGTTGCACTTCGGTATTCGCGAGCAGGGGGCGGCCGCAATTG
TGAACGGTATCGTGCTATCTTCGCCAACCCGTGCTTTCTCTGGGACGTTCTTCGTATTCTCGGATTACCAGCGTCCTGCA
GTCCGTCTTTCAGCTCTCATGGGTGTACCTGCACTGTATATCTGGACTCACGACTCCATTGGTGTTGGCGAAGACGGGCC
CACCCACCAACCAATCGAACATCTCAGCTCACTGCGCGCAATTCCTGGATTCGACGTTGTACGCCCTGCGGATGCGAACG
AAACTGCGGTTGCTTGGCGTACTATTCTTGAGAAGAAAGACCGCCCTGCCGGCCTAGTACTTTCTCGCCAGAACCTACCG
GTTTGGGCTCGTGAGGATATTCATTCAGACACTGAAGGCGAAAAATTTGCTTCCGCAGAAGGTACTGCGCGCGGAGGTTA
TGTTATGGCTGACACCGAGGGAACTCCAGATGTCATCCTGATCGCAACTGGGTCTGAAGTTGAAATTGCCCTCGAAGCCC
GCCACAAGCTCTCAGAAAAAGGCATTGCAGCCCGAGTTGTTTCAATGCCTTCCCGCGAATGGTTCAACGAGCAGTCAAAC
GAATACCGAGAATCAGTTCTGCCTTCCTCGGTTGCAGCACGCGTCTCAGTTGAAGCCGGTTTGGGCATGAGCTGGTACGA
TTTGCTCGGCTCTGCAGGACGTGCTGTCTCAATTGAACACTTTGGGGCTTCTGCCGATGCTAAGACTTTGTACCGTGAGT
TTGGTATTACCCCTGAAGCCGTCGTGACTGCTGCTGAAGAATCTATCGCCGCAGCCAAATAG

Protein sequence :
MTYHQAKGQYVTNPNEKFEWTEVDQRAVDTARLLAADAVEKVGSGHPGTAMSLAPVAYLLFQKVMNQDPNDDRWEGRDRF
ILSPGHTSLTLYTQLFMGGYGLEMEDLESLRTWDALTPGHPEYKHTKGVEITTGPLGQGLASAVGFAYAQRYMRGLFDPE
SPVGASPFDHYVYCIASEGDVQEGVTAEASALAGHQELGNLIVLWDRNHISIEEDTDVAFTEDVPARYRAYGWDVQHVDW
TKTGNYVEDVQELYNAIERAKTVTDKPSFIEVRTIIGYPAPNKQNTGSVHGSKLGAEEIVETKKVLGFDPEKSFFIEDEV
LAHTRELRERGAAAHKVWNEKFEAWAQANPERAKLYNRLVSGEMPVDYKAAFPVFEPGTSLATRAASGKVINAIADTFPE
LWGGSADLAGSNLTTINNAESFNPVSHSTEDWTGNPYGRVLHFGIREQGAAAIVNGIVLSSPTRAFSGTFFVFSDYQRPA
VRLSALMGVPALYIWTHDSIGVGEDGPTHQPIEHLSSLRAIPGFDVVRPADANETAVAWRTILEKKDRPAGLVLSRQNLP
VWAREDIHSDTEGEKFASAEGTARGGYVMADTEGTPDVILIATGSEVEIALEARHKLSEKGIAARVVSMPSREWFNEQSN
EYRESVLPSSVAARVSVEAGLGMSWYDLLGSAGRAVSIEHFGASADAKTLYREFGITPEAVVTAAEESIAAAK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 8e-117 42
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 1e-113 41