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Name : pyk (HMPREF0733_11827) Accession : YP_003984718.1 Strain : Rothia dentocariosa ATCC 17931 Genome accession: NC_014643 Putative virulence/resistance : Virulence Product : pyruvate kinase Function : - COG functional category : G : Carbohydrate transport and metabolism COG ID : COG0469 EC number : 2.7.1.40 Position : 2023220 - 2024698 bp Length : 1479 bp Strand : + Note : COG: COG0469; Pfam: PF00224,PF02887; InterPro: IPR001697 DNA sequence : ATGAGGCGCGCAAAAATCGTTGCAACCATTGGTCCGGCTATTTCTTCTCCCGAAAAAATTGCGGAAGCGATCAAGGCGGG TATGAACGTTTCCCGTCTGAATATGAGTCACGGTGACCATGACGTTCACACTAACTCTTACACAACTATCCGTGAACAAT CCGCGGCGTTGGGGAAAGAAGTAGCTATTCTTGCTGATCTGCAAGGTCCTAAGATCCGTTTGGAGCGCTTTGTAAACGGG GAAGAATATCTAAAGCCTGGCGCTGATTTTACGATTACTTCTGAGGACGTTGAGGGTACCAAGGATATCTGTGGTACGAC TTATAAAGGTCTTCCTGGCGATGTGAAGCCTGGCGATAAACTTTTGCTGGATGACGGTAAGATCCAACTGGAAGCCGTTG AAGTAACTCCAACTCGTGTTCGCACTCGTGTGATTGTAGGCGGACCTATTTCAAACAATAAAGGCATCAACCTTCCTGGG GCGGCCGTTTCTCTTCCCGCACTGACCGAGAAGGATGAGGCTGACCTTCGTTTTGCCCTGAATTTGGGCGTAGATATTAT TGCTCTTTCCTTTGTACGTAGCGGGAAAGACGTAAACCGCGTTCATGAGATCATGGCCGAAGAGGGTATCCGTATTCCGG TGATTGCCAAGATCGAAAAGCCTCAAGCCGTTGATAATCTGCAAGATATTATCGACAAGTTTGATGGCATCATGGTCGCC CGTGGCGACCTTGGCGTGGAACTGCCGTTCTCTGAGGTGCCACTGGTTCAGAAGAAAGCTATTGAGATGGCTCGTCGCTG GGCTAAGCCCGTTATCGTGGCAACTCAGGTACTTGAGTCCATGATCTCTAGCCCGACTCCTACGCGCGCGGAAGTCTCTG ACTGTGCAAACGCAATCTTGGATGGCGCCGATGCGGTGATGCTCTCCGGCGAGACTTCGGTAGGCAATTACCCCATTATT ACCATTGCGGCAATGGCCTCCATTATTCGTGATACTGAGGAAAAAGGTCTATACCGCGTACCACAGCTGGACCGTAAGCC CCGTACCCGTGGTGGTGCCATCACGCGTGCAGCTGTAAACATTGCGGAACAATTGGATGTAGATTACATTAGTACTTTTA CCCAGACGGGTGACTCAGCACGCCGTTTAGCACGTCTACGCCCTGCGCAGCCGGTACTTGCTTTCACCCCCAACCCAAAG GTGCGTGCTTTTATCTCACTGTTGTGGGGTGTTGAAGCTGCGCATGCGCCGGTGGCGACCAACATTGACGGTACGACCGA CATCGTAAATGACTACCTGGTCGAGCATAAGCTCGCAGAACCGGGTGATCTTATTGTGATTGCTGCAGGTTCGCCTCCCG GGGTGGCGGGATCAACCAATATGGTTAAGGTACACCGTATTAAGGAACAGGGTTCCGGCGAACATGAACCGGAAGAGCGT GAGCACCTGCGCCCCTACGGGGAAGACGAACATAAGTAA Protein sequence : MRRAKIVATIGPAISSPEKIAEAIKAGMNVSRLNMSHGDHDVHTNSYTTIREQSAALGKEVAILADLQGPKIRLERFVNG EEYLKPGADFTITSEDVEGTKDICGTTYKGLPGDVKPGDKLLLDDGKIQLEAVEVTPTRVRTRVIVGGPISNNKGINLPG AAVSLPALTEKDEADLRFALNLGVDIIALSFVRSGKDVNRVHEIMAEEGIRIPVIAKIEKPQAVDNLQDIIDKFDGIMVA RGDLGVELPFSEVPLVQKKAIEMARRWAKPVIVATQVLESMISSPTPTRAEVSDCANAILDGADAVMLSGETSVGNYPII TIAAMASIIRDTEEKGLYRVPQLDRKPRTRGGAITRAAVNIAEQLDVDYISTFTQTGDSARRLARLRPAQPVLAFTPNPK VRAFISLLWGVEAAHAPVATNIDGTTDIVNDYLVEHKLAEPGDLIVIAAGSPPGVAGSTNMVKVHRIKEQGSGEHEPEER EHLRPYGEDEHK |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| STY1744 | NP_456147.1 | pyruvate kinase | Not tested | SPI-2 | Protein | 4e-61 | 45 |
| pykF | YP_216386.1 | pyruvate kinase | Not tested | SPI-2 | Protein | 1e-61 | 45 |
| pykF | NP_805051.1 | pyruvate kinase | Not tested | SPI-2 | Protein | 1e-61 | 45 |
| pykF | CAA68205.1 | pyruvate kinase like protein | Not tested | SPI-2 | Protein | 1e-61 | 45 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| pyk | YP_003984718.1 | pyruvate kinase | VFG0479 | Protein | 6e-62 | 45 |
