Gene Information

Name : tpx (HMPREF0733_10162)
Accession : YP_003983054.1
Strain : Rothia dentocariosa ATCC 17931
Genome accession: NC_014643
Putative virulence/resistance : Virulence
Product : thiol peroxidase
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG2077
EC number : 1.11.1.-
Position : 186546 - 187127 bp
Length : 582 bp
Strand : -
Note : COG: COG2077; Pfam: PF08534; InterPro: IPR012335

DNA sequence : 
ATGTACGACGAGACCGCGCGGCCCGGCTCTTACGCGACAGTTCCCCTTGCGCAGAGGCAGAGAACGCGCGACAATGAGGA
AATGGCTGAAATTACTTTTCAAAATAACCTTGCAGTTCACACCAGCGGCAACCTTCCCGCCATCGGTTCTAAGGTCCCCG
CATTCTCCGTACTCGACGCCGACCTCGCTGAGGTCACCGGCGCCCAGTTCTCGGGTAAGAACCTCGTGCTGAATATCTTC
CCCTCGGTCGATACCGGCGTATGCGCCGCCTCGGTTCGCAACTTCAACAAAGAAGCCGCCGGTCTTGATAACACCGTTGT
CGTGAACGTTTCACACGATCTTCCGTTCGCGCTTGGTCGTTTCTGTGCCGCTGAGGGCATCGAGAACGTTGTTACCACCT
CCGCATTCCGCTCATCCTTCGGGCAGGACTTCGGCGTGACAATGACCGACGGACCTCTCGAAGGGCTCCTTGCTCGCGCC
GTCGTAGTCGTGAACCCCGCCGGTGAGGTAGTGTACACCGAGCTCGTTCCCGAAATCACCAACGAACCTAATTACGAGGC
TGCGCTCGCAGCTCTTAAGTAA

Protein sequence : 
MYDETARPGSYATVPLAQRQRTRDNEEMAEITFQNNLAVHTSGNLPAIGSKVPAFSVLDADLAEVTGAQFSGKNLVLNIF
PSVDTGVCAASVRNFNKEAAGLDNTVVVNVSHDLPFALGRFCAAEGIENVVTTSAFRSSFGQDFGVTMTDGPLEGLLARA
VVVVNPAGEVVYTELVPEITNEPNYEAALAALK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tpx YP_001216305.1 thiol peroxidase Not tested VPI-1 Protein 2e-30 45
tpx NP_230472.1 thiol peroxidase Virulence VPI-1 Protein 1e-30 45
tagD AAK20751.1 toxR-activated gene D protein Virulence VPI Protein 2e-30 45
tagD AAK20781.1 toxR-activated gene D protein Virulence VPI Protein 8e-31 45

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
tpx YP_003983054.1 thiol peroxidase VFG0087 Protein 3e-31 45