Gene Information

Name : megL2 (AXYL_04293)
Accession : YP_003980327.1
Strain : Achromobacter xylosoxidans A8
Genome accession: NC_014640
Putative virulence/resistance : Resistance
Product : methionine gamma-lyase 2
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 4.4.1.11
Position : 4592050 - 4593240 bp
Length : 1191 bp
Strand : -
Note : -

DNA sequence :
ATGACCGAGTCCACGCAACACGGCTTCGCCACGCGCGCCATCCACCTGGGCTACGACCCGCTGGACGAGCAGGGCGCGCT
GGCGCCGCCTCTCTACCTGACCTCCACCTACACCCAGGACAGCATCGAGGCCTTCGACCAGATCCGCCTGGGCGAGAAGC
AGGGCTACGTCTACGGCCGCACCCGCAATCCGACGCAGGCGTTGCTGGAAGAGCGGCTGGCGTCGCTGGAGGGCGCCGAA
GCGGGCGTTGTGACCGCTTCCGGCATGGCGGCGATTTCGGCCACCCTGTTCTCGCTCCTGCAAAGCGGCGACGAGATCGT
GGTGGACCAGATCGTGTACGGCACGGCCTTCACCCTGTTCACGCAGGGCCTGGCGCGGTTTGGCGTGCGCGCGGTGTTTG
CCGACTTCACCCGTCCCGAGACCGTGGCCGCGGCCCTCGGCCCCAAGACGCGTGCCGTCTACTTTGAAACGCCCGCCAAT
CCGAATCTGCGTCTGGTGGATATCGCGGCGGTGTCCGCCATCGCCCGCGGCAAAGGTGTGCTGACTATCGTCGACAACAC
CTTCGCCACGCCGGTGCTGCAGCGGCCGCTGGAGCATGGCGCGGACATCGTGCTGCATTCGGCCACCAAGTACCTGGGCG
GCCACGGCGACCTGCTGGCCGGCGCGGTGCTGGGCCGCAAGGAGCACATCGATGCCATCCGGCTGCAGGGGTTGCGCTAC
TTCACCGGCGCCACCTTGTCGCCTTTCACGGCTTTCCTGGTGCTGCGCGGGATCAAGACGCTGGAATTGCGCGTGGCGCG
CCATAGCGAATCCGCCTTGCGGGTGGCCAAGCTGCTGCGCGAGCATGCGGCGGTGGCCGACGTGTTCTATCCCGGCTTGG
CCGATACTGCGGGGGCCGAGATCGCGCGCCGCCAGCAATCGGCGGGCGGCGGCCTGGTCGCGTTCGAGTTGAAGGGCGGA
TTGACCGCTGGCCGCAAGCTGCTCAATAGTCTGAAGCTGGCGCGCATCGCAGTCAGCCTGGGCGATCCTGAAACCCTGAT
CCAGCATCCCGCGTCGATGACGCACGCCAGTTACACGGCTGAGGACCGCGAACGCTATGGATTGTCCGAGGGCTTGCTGC
GCCTGTCGGTGGGCCTGGAGACGCCTGAAGACATCCTGTCCGATCTCAGGCAGGGCCTGGACCGGCTGTAG

Protein sequence :
MTESTQHGFATRAIHLGYDPLDEQGALAPPLYLTSTYTQDSIEAFDQIRLGEKQGYVYGRTRNPTQALLEERLASLEGAE
AGVVTASGMAAISATLFSLLQSGDEIVVDQIVYGTAFTLFTQGLARFGVRAVFADFTRPETVAAALGPKTRAVYFETPAN
PNLRLVDIAAVSAIARGKGVLTIVDNTFATPVLQRPLEHGADIVLHSATKYLGGHGDLLAGAVLGRKEHIDAIRLQGLRY
FTGATLSPFTAFLVLRGIKTLELRVARHSESALRVAKLLREHAAVADVFYPGLADTAGAEIARRQQSAGGGLVAFELKGG
LTAGRKLLNSLKLARIAVSLGDPETLIQHPASMTHASYTAEDRERYGLSEGLLRLSVGLETPEDILSDLRQGLDRL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 7e-64 42
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 6e-65 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
megL2 YP_003980327.1 methionine gamma-lyase 2 BAC0207 Protein 2e-95 54