Gene Information

Name : aadA (AXYL_03722)
Accession : YP_003979757.1
Strain : Achromobacter xylosoxidans A8
Genome accession: NC_014640
Putative virulence/resistance : Resistance
Product : streptomycin 3''-adenylyltransferase
Function : -
COG functional category : -
COG ID : -
EC number : 2.7.7.47
Position : 3997379 - 3998179 bp
Length : 801 bp
Strand : +
Note : -

DNA sequence : 
ATGGCCCTACTGATCCCTCCTCCCATCGTCCCCCAGATCGCGCAAGCCAAAAGCCTCATCGAACGGCATCTCGGCACTGG
CCTTGTCGCCATCCACCTGTTCGGCTCCGCCGTGGACGGCGGGCTGCAACCCCACAGCGATATTGACCTGCTCGTCAGCG
TGGCCCAGCCGCCCGGCGAGGCCGCACTCCGCGCTTTGGCCATGGCCTTGCTGGCCGTATCCGCTCCACCGGGTTCATCG
CCCAGCTTGCGCGCACTGGAAGTCACCGTACTGGCGCGTGAACAGATCGTGCCCTGGCGCCACCCGGCCCGGCGCGAACT
CCAGTTCGGCGAGTGGCTGCGCGCCGACCTGGAGGCGGGCGTGGTCGAACCGCCCATGATGGACCACGACCTGGCCATCC
TGCTCACCAAGGCCCGCGGCCACAGCATCCCCATCATGGGCCCGCAGGCCGACCAGATTTTCGAGGCCGTGCCCCGGGAG
GATCTGAGGCGGGCGCTGCTCGACACCGTTGCGCAGTGGAACGCGCCCGAAGACTGGGCCGGCGATGAAAAGCACATCAT
CCTCGCGCTGGCACGCATCTGGTACACGGCCTTATCCGGCGGCATCGCCTCCAAGGAACTGGCGGCGACGTGGCTGCTGG
AACGGCTGGAACCGCCCTATCGCCCCGTCCTCGGCAAGGCACGGGCGATCTATCTGGGGCAAGAGGAAGACGATCTGGCG
CAGCGGCATCAGGCCGAAACAGCGGCGTTCATCGTCCACGCGCGCGGCGCGATTGAACGGACTTGTGCCGCTTCACGATA
G

Protein sequence : 
MALLIPPPIVPQIAQAKSLIERHLGTGLVAIHLFGSAVDGGLQPHSDIDLLVSVAQPPGEAALRALAMALLAVSAPPGSS
PSLRALEVTVLAREQIVPWRHPARRELQFGEWLRADLEAGVVEPPMMDHDLAILLTKARGHSIPIMGPQADQIFEAVPRE
DLRRALLDTVAQWNAPEDWAGDEKHIILALARIWYTALSGGIASKELAATWLLERLEPPYRPVLGKARAIYLGQEEDDLA
QRHQAETAAFIVHARGAIERTCAASR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
aadA7 AGK06932.1 aminoglycoside adenyltransferase Not tested SGI1 Protein 3e-56 56
aadA7 AGK06969.1 aminoglycoside adenyltransferase Not tested SGI1 Protein 3e-56 56
aadA7 AGK07015.1 aminoglycoside adenyltransferase Not tested SGI1 Protein 3e-56 56
aadA7 AGK07073.1 aminoglycoside adenyltransferase Not tested SGI1 Protein 3e-56 56
aadA7 AAR21854.1 aminoglycoside (3'')(9) adenylyltransferase; AAD(3'')(9) Not tested SGI1 Protein 3e-56 56
aadA7 AAT37846.1 aminoglycoside adenyltransferase Not tested Class I integron Protein 3e-56 56
aadA7 AGF35062.1 aminoglycoside adenyltransferase Not tested SGI1 Protein 3e-56 56
aadA25 YP_005176241.1 aminoglycoside 3''-O-adenyltransferase protein Not tested ICEPmu1 Protein 2e-61 55
aadA1 ACY75515.1 aminoglycoside adenyltransferase Not tested Tn6060 Protein 2e-61 54
aadA1 CAD92142.1 aminoglycoside adenyltransferase Not tested Not named Protein 2e-61 54
aadA1 YP_005797133.1 aminoglycoside 3'-adenyltransferase Not tested AbaR4e Protein 2e-61 54
aadDA1 CAJ77087.1 Aminoglycoside 3-adenylyltransferase Not tested AbaR1 Protein 1e-61 54
aadA1 YP_005797149.1 aminoglycoside 3'-adenyltransferase Not tested AbaR4e Protein 2e-61 54
aadA1 ACV89835.1 AadA1 aminoglycoside (3')(9) adenylyltransferase Not tested AbaR7 Protein 1e-61 54
aadA1 YP_006098376.1 aminoglycoside adenylyltransferase Not tested Tn2411 Protein 2e-61 54
unnamed AFV53113.1 AadA1 aminoglycoside (3') adenyltransferase Not tested AbGRI2-1 Protein 1e-61 54
aadA1 ACN81025.1 AadA1 aminoglycoside (3')(9) adenylyltransferase Not tested AbaR5 Protein 2e-61 54
aadA1 AGK36646.1 AadA1 aminoglycoside (3')(9) adenylyltransferase Not tested AbaR26 Protein 1e-61 54
aadA2 ACF06158.1 aminoglycoside 3''-adenyltransferase Not tested Tn5036-like Protein 1e-59 54
aadA2 AAK02046.1 streptomycin/spectinomycin resistance protein Not tested SGI1 Protein 1e-59 54
aadA2 AGF35027.1 AadA2 aminoglycoside adenylyltransferase Not tested SGI1 Protein 1e-59 54
aadA1 CAJ77048.1 Aminoglycoside adenylyltransferase Not tested AbaR1 Protein 1e-61 54
aadA1 AAL08435.1 streptomycin adenyltransferase AadA1 Not tested SRL Protein 3e-56 50

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
aadA YP_003979757.1 streptomycin 3''-adenylyltransferase DQ865198.gene.p01 Protein 2e-65 59
aadA YP_003979757.1 streptomycin 3''-adenylyltransferase AY139598.1.gene2.p01 Protein 3e-65 59
aadA YP_003979757.1 streptomycin 3''-adenylyltransferase NC_010558.1.6275994. Protein 2e-65 59
aadA YP_003979757.1 streptomycin 3''-adenylyltransferase U37105.2.gene4.p01 Protein 4e-54 57
aadA YP_003979757.1 streptomycin 3''-adenylyltransferase AJ704863.gene12.p01 Protein 2e-58 54
aadA YP_003979757.1 streptomycin 3''-adenylyltransferase AM932669.1.gene3.p01 Protein 9e-62 54
aadA YP_003979757.1 streptomycin 3''-adenylyltransferase AF294653.1.gene3.p01 Protein 6e-60 54
aadA YP_003979757.1 streptomycin 3''-adenylyltransferase AJ584652.2.gene7.p01 Protein 5e-60 54
aadA YP_003979757.1 streptomycin 3''-adenylyltransferase AF047479.2.orf1.gene Protein 3e-60 54
aadA YP_003979757.1 streptomycin 3''-adenylyltransferase Y18050.2.gene6.p01 Protein 1e-61 54
aadA YP_003979757.1 streptomycin 3''-adenylyltransferase EU118119.1.orf1.gene Protein 6e-60 54
aadA YP_003979757.1 streptomycin 3''-adenylyltransferase AY123251.gene3.p01 Protein 9e-62 54
aadA YP_003979757.1 streptomycin 3''-adenylyltransferase NC_010410.6003168.p0 Protein 9e-62 54
aadA YP_003979757.1 streptomycin 3''-adenylyltransferase JN596991.2.gene3.p01 Protein 1e-61 54
aadA YP_003979757.1 streptomycin 3''-adenylyltransferase FR748153.1.gene5.p01 Protein 1e-61 54
aadA YP_003979757.1 streptomycin 3''-adenylyltransferase AF313471.1.gene3.p01 Protein 9e-62 54
aadA YP_003979757.1 streptomycin 3''-adenylyltransferase AY339625.2.gene17.p0 Protein 9e-62 54
aadA YP_003979757.1 streptomycin 3''-adenylyltransferase NC_010410.6003170.p0 Protein 6e-62 54
aadA YP_003979757.1 streptomycin 3''-adenylyltransferase AF174129.3.gene3.p01 Protein 2e-59 53
aadA YP_003979757.1 streptomycin 3''-adenylyltransferase AY263741.gene.p01 Protein 2e-58 53
aadA YP_003979757.1 streptomycin 3''-adenylyltransferase NC_003198.gene.p01 Protein 2e-40 49
aadA YP_003979757.1 streptomycin 3''-adenylyltransferase NC_010410.6002671.p0 Protein 1e-24 41
aadA YP_003979757.1 streptomycin 3''-adenylyltransferase NC_010400.5986843.p0 Protein 5e-25 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
aadA YP_003979757.1 streptomycin 3''-adenylyltransferase VFG1026 Protein 2e-56 50