Gene Information

Name : AXYL_03627 (AXYL_03627)
Accession : YP_003979662.1
Strain : Achromobacter xylosoxidans A8
Genome accession: NC_014640
Putative virulence/resistance : Resistance
Product : tetracycline resistance protein, class A
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG2814
EC number : -
Position : 3887559 - 3888815 bp
Length : 1257 bp
Strand : +
Note : -

DNA sequence :
GTGCCGAAAAATTTATCAACGATAAATAAATACGAATCAGCACATGAAATCCACACCCCTACCCGAAGGCCGGACGTGAG
AGCCGGCCATGCCCTGGTTATCCTGAGCACCGTTGCGCTGGACGCGGTCGGCATAGGCCTGGTCATGCCCGTCCTGCCCG
GCCTGCTGCGAGGCCTGGTCCACTCGGAGGAGATTGCCGGCCACTATGGGGCCTTGCTCGCGGCGTATGCGCTGATGCAG
TTCCTCTGCGCCCCGGCGCTGGGCGCGCTGTCCGACCGCTATGGGCGGCGGCCGATCCTGCTGCTCTCGCTGGCGGGCGC
CGCCATCGACTACCTGATCATGGCGACGGCCCCGACCCTGCTGGTCCTGTATCTGGGGCGGCTCGTCGCCGGCATCACCG
GCGCCACCGGTGCGGTGGCGGGCGCCTGCATCGCCGACCTCACCAAGGAGGGCGAGCGGGCGCGCTACTTCGGCCTGATG
AGCGCCTGCTTCGGCGTCGGCATGATTGCCGGTCCCGTCATCGGCGGCCTGTTGGGCGGCATCTCGCCGCAGCTGCCGTT
CCTGGCGGCCGCGATCCTCAACGGCCTGAATTTTCTGATGGGGTGCTTCCTGTTGCCGGAGTCGCATCGCGGCGAGCGGC
GGCCGCTGTCGCTGAAGGCGCTCATGCCCGCTTCCTCTTTCCTGTGGGCGCGCGGCAAGACGGCGGTGATCGCCTTGATG
GCCGTCTTTTTCGTCATGCAGTTCGTGGGACAGGTGCCCGCCACGCTGTGGGTCATATATGGCGAAGACCGCTACCAGTG
GGATGCCGCCACGGTCGGCCTGTCGCTGGCCGCGTTCGGCGCGCTGCACGCCCTGGTCCAGGCGCTGGCCACCGGCCCCG
CCACGGCGCGACTGGGAGAAAAGCGGACGCTGTTGCTGGGCATGGCCGCCGATGCCCTGGGCTATGTCCTGCTGGCGTTC
GCGACGCGCGGATGGATGGCCTTCCCCATCATGGTCCTGCTGGCGTCGGGCGGCATCGGCATGCCGGCGTTGCAGGCCAT
GCTGTCGGCGCGGGTCGAGCAGGAACGCCAAGGCCAGTTGCAGGGCGCGCTCGCCGCGTTGTCGAGCCTCAGCGCGATCG
TCGGGCCCCTGGCCATCACGGCGCTCTATGCCGCCACGCTGAACGTGTGGAAAGGATGGGCATGGATCGCGGGCGCCGGG
CTGTATTTTGCCTGCCTGCCGGCCTTGCGCCGCAGGGCTTCGCAAGGCAAGTCTTAG

Protein sequence :
MPKNLSTINKYESAHEIHTPTRRPDVRAGHALVILSTVALDAVGIGLVMPVLPGLLRGLVHSEEIAGHYGALLAAYALMQ
FLCAPALGALSDRYGRRPILLLSLAGAAIDYLIMATAPTLLVLYLGRLVAGITGATGAVAGACIADLTKEGERARYFGLM
SACFGVGMIAGPVIGGLLGGISPQLPFLAAAILNGLNFLMGCFLLPESHRGERRPLSLKALMPASSFLWARGKTAVIALM
AVFFVMQFVGQVPATLWVIYGEDRYQWDAATVGLSLAAFGALHALVQALATGPATARLGEKRTLLLGMAADALGYVLLAF
ATRGWMAFPIMVLLASGGIGMPALQAMLSARVEQERQGQLQGALAALSSLSAIVGPLAITALYAATLNVWKGWAWIAGAG
LYFACLPALRRRASQGKS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tetA YP_006098396.1 tetracycline resistance protein Not tested Tn2411 Protein 4e-114 77
tetA(A) ACK44537.1 TetA(A) Not tested SGI1 Protein 3e-114 77
tetA(A) AGK07027.1 TetA(A) Not tested SGI1 Protein 3e-114 77
tetA(A) AGK07085.1 TetA(A) Not tested SGI1 Protein 3e-114 77
tetA CAJ77066.1 Tetracycline resistance protein Not tested AbaR1 Protein 7e-119 73
tetA(A) ACN81011.1 TetA(A) Not tested AbaR5 Protein 9e-119 73
tet(G) AAK02051.1 tetracycline resistance protein Not tested SGI1 Protein 6e-91 64
tetA(G) ABZ01843.1 TetA(G) Not tested SGI2 Protein 6e-91 64
tetA(G) AGK06974.1 TetA(G) Not tested SGI1 Protein 6e-91 64
tetA(G) AGK07104.1 TetA(G) Not tested SGI1 Protein 6e-91 64
tetA CAJ77034.1 Tetracycline resistance protein Not tested AbaR1 Protein 2e-93 63
tetA YP_005797160.1 tetracycline resistance protein, class G (TETA(G)) Not tested AbaR4e Protein 1e-65 47
tetA(B) AEZ06045.1 tetracycline efflux protein Not tested Tn6167 Protein 5e-66 46
tetA(B) AAL08445.1 tetracycline resistance protein TetA(B) Not tested SRL Protein 5e-66 46
tetB AEA34667.1 tetracycline resistance determinant Not tested Not named Protein 4e-66 46
tetA(B) AEQ20905.1 tetracycline resistance protein Not tested Tn6166 Protein 5e-66 46
BJAB07104_00277 YP_008207742.1 Permeases of the major facilitator superfamily Not tested AbaR25 Protein 5e-66 46
BJAB0868_00281 YP_008211607.1 Permeases of the major facilitator superfamily Not tested AbaR26 Protein 5e-66 46
tetA(B) AFH57202.1 tetracycline resistance protein Not tested AbaR4a Protein 2e-66 45
ABZJ_00260 YP_005524216.1 Tetracycline resistance protein, class B (TETA(B) ) (Metal-tetracycline/H(+) antiporter) Not tested AbaR22 Protein 3e-66 45
tet(H) YP_005176248.1 tetracycline efflux protein, class H Not tested ICEPmu1 Protein 6e-56 44

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
AXYL_03627 YP_003979662.1 tetracycline resistance protein, class A NC_011586.7045189.p0 Protein 4e-108 76
AXYL_03627 YP_003979662.1 tetracycline resistance protein, class A X75761.gene.p01 Protein 4e-114 76
AXYL_03627 YP_003979662.1 tetracycline resistance protein, class A Y19114.gene.p01 Protein 6e-108 74
AXYL_03627 YP_003979662.1 tetracycline resistance protein, class A AF534183.gene.p01 Protein 5e-119 73
AXYL_03627 YP_003979662.1 tetracycline resistance protein, class A NC_010410.6002597.p0 Protein 4e-119 73
AXYL_03627 YP_003979662.1 tetracycline resistance protein, class A CP001485.1.gene2821. Protein 4e-119 73
AXYL_03627 YP_003979662.1 tetracycline resistance protein, class A NC_010410.6002612.p0 Protein 1e-93 63
AXYL_03627 YP_003979662.1 tetracycline resistance protein, class A AF133140.gene.p01 Protein 1e-93 63
AXYL_03627 YP_003979662.1 tetracycline resistance protein, class A AF133139.gene.p01 Protein 2e-95 63
AXYL_03627 YP_003979662.1 tetracycline resistance protein, class A AY264780.2.gene3.p01 Protein 2e-75 56
AXYL_03627 YP_003979662.1 tetracycline resistance protein, class A AF070999.gene.p01 Protein 1e-76 54
AXYL_03627 YP_003979662.1 tetracycline resistance protein, class A Y19116.gene.p01 Protein 9e-68 53
AXYL_03627 YP_003979662.1 tetracycline resistance protein, class A L06940.gene.p01 Protein 1e-68 53
AXYL_03627 YP_003979662.1 tetracycline resistance protein, class A AY743590.gene.p01 Protein 2e-63 51
AXYL_03627 YP_003979662.1 tetracycline resistance protein, class A L06798.gene.p01 Protein 4e-58 49
AXYL_03627 YP_003979662.1 tetracycline resistance protein, class A AF090987.gene.p01 Protein 5e-56 47
AXYL_03627 YP_003979662.1 tetracycline resistance protein, class A AJ420072.gene.p01 Protein 1e-60 46
AXYL_03627 YP_003979662.1 tetracycline resistance protein, class A CP004022.1.gene2534. Protein 5e-59 46
AXYL_03627 YP_003979662.1 tetracycline resistance protein, class A AF038993.gene.p01 Protein 6e-59 46
AXYL_03627 YP_003979662.1 tetracycline resistance protein, class A AB084246.gene.p01 Protein 3e-66 46
AXYL_03627 YP_003979662.1 tetracycline resistance protein, class A V00611.gene.p01 Protein 6e-66 46
AXYL_03627 YP_003979662.1 tetracycline resistance protein, class A NC_010558.1.6275971. Protein 3e-66 46
AXYL_03627 YP_003979662.1 tetracycline resistance protein, class A AF121000.gene.p01 Protein 2e-61 45
AXYL_03627 YP_003979662.1 tetracycline resistance protein, class A Y15510.gene.p01 Protein 7e-57 45
AXYL_03627 YP_003979662.1 tetracycline resistance protein, class A NC_011595.7059241.p0 Protein 1e-53 44
AXYL_03627 YP_003979662.1 tetracycline resistance protein, class A NC_011586.7043399.p0 Protein 8e-54 44
AXYL_03627 YP_003979662.1 tetracycline resistance protein, class A NC_010410.6003291.p0 Protein 1e-53 44
AXYL_03627 YP_003979662.1 tetracycline resistance protein, class A NC_009085.4918440.p0 Protein 2e-50 43
AXYL_03627 YP_003979662.1 tetracycline resistance protein, class A AJ250203.gene.p01 Protein 8e-51 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
AXYL_03627 YP_003979662.1 tetracycline resistance protein, class A VFG1036 Protein 3e-66 46