Gene Information

Name : cadA1 (AXYL_02618)
Accession : YP_003978653.1
Strain : Achromobacter xylosoxidans A8
Genome accession: NC_014640
Putative virulence/resistance : Resistance
Product : cadmium-translocating P-type ATPase 1
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG2217
EC number : 3.6.3.-
Position : 2799334 - 2801421 bp
Length : 2088 bp
Strand : -
Note : -

DNA sequence :
ATGGACTGCCCCACCGAGGAAACTCTGATCCGCAAGAAGCTGGACAACATGGCCGACGTGCACGCGCTGGACTTCAACCT
GATGCAGCGCGTGCTGACGGTGGTGCACGCCGAAGGCGCGCTGGACCGCGTCATGGCCGCCATCAAGTCGCTGGACATGA
CGCCCGAACCCCTGGCCGACAACGCGCCCGGCACGCCCGCCCCCGCCGCCAAACCCGTGAACTGGTGGATGATCGGCGGC
GCGGGTGTCCTGGCCGCGCTGTCCGAACTGTCGCATTTCGCCGGCTGGCCGCTGGGCGTCACCGCGGCCCTGGCCGTGGC
CGCCATCCTGGCCTGCGGCATCACCACCTACCGCAAGGGCTGGATTGCCGTGCGCAACGGCAATCTCAACATCAATGCCC
TGATGAGCATCGCCGTCACCGGCGCCGTGCTGATCGGCCAATGGCCCGAAGCAGCCATGGTGATGTTCCTGTTCAATGTG
GCCGAGCTGATCGAAGCCCGCTCCCTGGACCGGGCGCGCAACGCGATCCGCGGCCTGCTGGATCTGGCGCCGGAAACCGC
CACCCTGCGCCAGGCCAATGGCGAATGGCTGGAAGTGCCTGCCGCCAGGCTGCAGGTAGGCGACATCGTGCGGGTACGCC
CGGGCGAACGCATTGCGGCCGACGGCATCATCGTCAGCGGCAGCTCGGCCGTGGACCAGTCGCCCATCACCGGCGAAAGC
CTGCCCGTCGAAAAAACGCAGGATGATCCGGTCTACGCCGCCACCGTCAACGCGGCCGGCTCCTTCGAATACCGCGTCAC
CGCGGCGGCCGGCAACACCACGCTCGCGCGCATCATCCACGCCGTCGAGCAGGCGCAAGGCGCGCGCGCGCCGACCCAGC
GCTTCATCGACCGCTTCTCGCGCATCTATACGCCCGCCGTGGTGGGCATCGCGGTGCTGGTCGCGGTGCTGCCGCCGCTG
TTCTGGGACCAGCCCTGGTTCGACGCGATCTACCGCGCCCTGGCGTTGCTGATCATCGCCTGCCCCTGCGCGCTGGTCAT
CTCCACGCCAGTCAGCATCGTCAGCGGCCTGACCGCAGCCTCGCGCCGCGGCATCCTGGTCAAGGGCGGCGTGTACCTCG
AAGAAGGCCGCAACCTGAAATGGCTGGCGCTGGACAAGACCGGCACGCTGACCCACGGCAAGCCGGTGCAGACCGACATC
CAGGATTGGGACCTGTCCGACCAGAGCCGCCAGCCTGCAACGCTGGTCGCGGCCAGCCTGGCGGCACGCTCCGACCACCC
GGTGTCCCTGGCCGTGGCCAACGCCGCGCGCGAAGCCGGCACGGTCCTGCTGGACGTGCAGGACTTCACCGCCCTGCCGG
GCCGCGGCGTCAGCGCGACCTTGGAGGGCGTCACCTTCCAGCTGGGCAACCGCCGCCTGATGCGCGAACTGGGCGTCTCC
AGCCCCAAGCTGGAAGCCCGTCTGGATGAACTGGAACGCCAAGGCAAGAGCGCCATCGCGTTGACCGACGGCAACCGCGT
GCTGGCCGTGGCCGCCGTGGCCGACACGGTCAAGCCGACCAGCACCGCCGCCATCGCCGACCTGCACGCCCTGGGCGTGC
GCACGCTGATGCTGACCGGCGACAACACACCTACCGCGCAAGCCATCGCGCAGCAAGTCGGCATCGACGAAGCCCGCGGC
GACCAGTTGCCCGAAGACAAGCTGGCCGCCATCGAAAGCAAGCTGGCGTCGGGCGGCCGCGTGGGCATGGTGGGCGACGG
CATCAACGACGCCCCCGCCCTGGCCCGCGCCGACATCGGCTTCGCCATGGGCGCGGCCGGCACTGGCACCGCCATCGAAA
CGGCCGACGTGGCCCTGATGGACGACGACCTGCGCAAGATCGGCACTTTCCTGCGCCTGTCCCACGCCACGCATCGCGTG
CTGGTGCAGAACATCGTGCTGGCGCTGGGCATCAAGGCCGTGTTCCTGGCCCTGGCCATGACCGGCAACGCCACGCTGTG
GATGGCGGTGTTCGCCGACGTGGGCGCCAGCCTGCTGGTGGTCGCGAACGGCCTGCGGCTGTTGCGGGCGGCGCCGGCCG
CCCATTGA

Protein sequence :
MDCPTEETLIRKKLDNMADVHALDFNLMQRVLTVVHAEGALDRVMAAIKSLDMTPEPLADNAPGTPAPAAKPVNWWMIGG
AGVLAALSELSHFAGWPLGVTAALAVAAILACGITTYRKGWIAVRNGNLNINALMSIAVTGAVLIGQWPEAAMVMFLFNV
AELIEARSLDRARNAIRGLLDLAPETATLRQANGEWLEVPAARLQVGDIVRVRPGERIAADGIIVSGSSAVDQSPITGES
LPVEKTQDDPVYAATVNAAGSFEYRVTAAAGNTTLARIIHAVEQAQGARAPTQRFIDRFSRIYTPAVVGIAVLVAVLPPL
FWDQPWFDAIYRALALLIIACPCALVISTPVSIVSGLTAASRRGILVKGGVYLEEGRNLKWLALDKTGTLTHGKPVQTDI
QDWDLSDQSRQPATLVAASLAARSDHPVSLAVANAAREAGTVLLDVQDFTALPGRGVSATLEGVTFQLGNRRLMRELGVS
SPKLEARLDELERQGKSAIALTDGNRVLAVAAVADTVKPTSTAAIADLHALGVRTLMLTGDNTPTAQAIAQQVGIDEARG
DQLPEDKLAAIESKLASGGRVGMVGDGINDAPALARADIGFAMGAAGTGTAIETADVALMDDDLRKIGTFLRLSHATHRV
LVQNIVLALGIKAVFLALAMTGNATLWMAVFADVGASLLVVANGLRLLRAAPAAH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ORF C97 AAN62190.1 putative metal-transporting P-type ATPase Not tested PAGI-2(C) Protein 0.0 65
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 9e-100 44
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 1e-102 42
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 1e-102 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
cadA1 YP_003978653.1 cadmium-translocating P-type ATPase 1 BAC0298 Protein 8e-178 65
cadA1 YP_003978653.1 cadmium-translocating P-type ATPase 1 BAC0461 Protein 1e-64 42