Gene Information

Name : topB1 (AXYL_01058)
Accession : YP_003977119.1
Strain : Achromobacter xylosoxidans A8
Genome accession: NC_014640
Putative virulence/resistance : Unknown
Product : DNA topoisomerase III 1
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0550
EC number : 5.99.1.2
Position : 1136791 - 1138821 bp
Length : 2031 bp
Strand : +
Note : -

DNA sequence :
ATGCGGCTGTTTCTGTGCGAGAAGCCCTCCCAGGGCAAAGACATCGGCCGGATTCTCGGCGCCACCCAGCGCGGTGAAGG
CTGCCTCAATGGCTCCGGCGTCACGGTCACCTGGTGCATCGGCCATCTCGTCGAAGCAGCAGCACCCGAGGTCTATGACG
CGGCGCTCAAGCGCTGGTCGCTGGAGCAGTTGCCCATCATTCCCCAGCAGTGGCGGGTCGAGGTCAAGCCGAAGACCGCC
ACGCAGTTCAAGGTCGTCAAGGCGCTTCTGGCGAAGGCGACCCACCTTGTCATTGCCACCGACGCCGACCGCGAGGGCGA
GCTGATCGCCCGCGAGATCATCGACCTGTGCGGCTACCGCGGTCCCATCGAACGCCTGTGGCTGTCGGCGCTCAACGATG
CGTCCATCCGCACCGCGCTCGCCAAGCTGCGGCCCTCGGCCGAGACACTGCCGATGTATTACTCGGCGCTGGCGCGCTCG
CGCGCCGACTGGCTTGTGGGCATGAACCTCAGCCGGCTGTTCACCGTGCTCGGGCGGCAAGCCGGCTACGACGGCGTGCT
GTCGGTCGGGCGTGTACAGACCCCGACGCTCAAACTCGTGGTGGACCGTGACCGAGAGATCGCGGCCTTCGTGTCCGTGC
CGTACTGGGCCATCGACGTGTCCTTGTCCGCAGGCGGTCAGACGTTCACCGCGCAGTGGGTGGCACCCGATGCCAGCGCC
GACGACGCCGGCCGCTGCCTGCAGCAGCCCATCGCACAGCAGGCCGCGCAGCAGATCCGCGCCGCGGGCAGTGCCCAGGT
GGTGTCGGTCGAAACCGAGCGCGTGCGCGAAGGCCCGCCGCTGCTGTTCGACCTGGGCACCTTGCAGGAAGTCTGTTCCA
AGCAGCTTGGGCTGGACGTGCAGGAGACACTGGAAATTGCCCAGGCCCTGTACGAGACGCACAAGGCCACGACGTACCCG
CGCTCGGATTCGGGCTACCTCCCCGAAAGCATGTTCGCCGAGGTGCCCACGGTCCTGGACAGCCTGCTAAAGACCGATCC
CACGCTGGCCCCGATCATGGGCCAGCTCGACCGCACCCAGCGCTCGCGCGCCTGGAACGACAGCAAGGTGACGGCGCACC
ACGGCATCATCCCGACGCTCGAACCCGCGAACCTCTCCGCCATGAGCGAGAAGGAGCAGGCGGTGTACCGGCTGATCCGG
GCGCATTACCTGGCCCAGTTCCTCCCGCACCACGAGTTCGACCGCACCGTGGCGGACCTCTCCTGCGGCCAGCAGAAGCT
GGTGGCCACGGGCAAGCAGGTCGTCGTCAAGGGCTGGCGCCTGGTGCTGGCCGAGCCAGAACGTGAAGGCAGCGCCGACG
AGGACGGCGATGCCCCGCGCAGCCAGGTGCTGCCCGCATTGCGCGACGGGATGGCATGTCAGGTCGCCGGGGCCGACATC
AAGGCCCTCAAGACGATGCCGCCCAAGCCCTATACCCAGGGCGAACTGGTCAAGGCGATGAAGGGCGTTGCGCGTTTCGT
GACCGACCCGCGCCTGAAGCAGAAGCTCAAGGACACGACGGGCATCGGCACCGAGGCGACGCGGGCCAACATCATCAGCG
GGCTGATCGCCCGCGGCTACATCGTGAAGAAGGGACGCTCCATCCGCGCATCGGATGCGGCGCTCACGCTGATAGACGCC
GTGCCCGCGGCGATTGCCGACCCCGGCACCACCGCCGTCTGGGAACAGGCGCTGGACATGATCGAGGCCGGACAACTCAC
CCTGGATGTGTTCATCGGCAAGCAGGCTGCATGGATTTCGCAGTTGATCGCGCAGTACGGCAGCACGTCCCTGTCCATCA
AGGTTCCCCAAGGACCGGCTTGTCCGCAGTGCGGCGCACCCACGCGCCAGCGCACCGGCAAGAGCGGCCCGTTCTGGTCG
TGCAGTCGCTACCCCGCCTGCAAAGGCACGCTGCCGGTGGCAACCGGCACGTCCAGGCGTGGTGCCTCGCGTCCACGCCG
TACCAGTGGCGGTGGCTGCAAAGGCGCCTGA

Protein sequence :
MRLFLCEKPSQGKDIGRILGATQRGEGCLNGSGVTVTWCIGHLVEAAAPEVYDAALKRWSLEQLPIIPQQWRVEVKPKTA
TQFKVVKALLAKATHLVIATDADREGELIAREIIDLCGYRGPIERLWLSALNDASIRTALAKLRPSAETLPMYYSALARS
RADWLVGMNLSRLFTVLGRQAGYDGVLSVGRVQTPTLKLVVDRDREIAAFVSVPYWAIDVSLSAGGQTFTAQWVAPDASA
DDAGRCLQQPIAQQAAQQIRAAGSAQVVSVETERVREGPPLLFDLGTLQEVCSKQLGLDVQETLEIAQALYETHKATTYP
RSDSGYLPESMFAEVPTVLDSLLKTDPTLAPIMGQLDRTQRSRAWNDSKVTAHHGIIPTLEPANLSAMSEKEQAVYRLIR
AHYLAQFLPHHEFDRTVADLSCGQQKLVATGKQVVVKGWRLVLAEPEREGSADEDGDAPRSQVLPALRDGMACQVAGADI
KALKTMPPKPYTQGELVKAMKGVARFVTDPRLKQKLKDTTGIGTEATRANIISGLIARGYIVKKGRSIRASDAALTLIDA
VPAAIADPGTTAVWEQALDMIEAGQLTLDVFIGKQAAWISQLIAQYGSTSLSIKVPQGPACPQCGAPTRQRTGKSGPFWS
CSRYPACKGTLPVATGTSRRGASRPRRTSGGGCKGA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
topB AAN62194.1 putative DNA topoisomerase III Not tested PAGI-2(C) Protein 0.0 88
topB AAN62317.1 putative DNA topoisomerase III Not tested PAGI-3(SG) Protein 0.0 75
pph56 CAI36097.1 Topoisomerase IA Not tested PPHGI-1 Protein 0.0 62
topB1 YP_005176228.1 DNA topoisomerase III Not tested ICEPmu1 Protein 2e-168 51
topB NP_458624.1 topoisomerase B Not tested SPI-7 Protein 1e-168 50
topB NP_807836.1 DNA topoisomerase III Not tested SPI-7 Protein 1e-168 50
topB AAF14809.1 topoisomerase B Not tested SPI-7 Protein 8e-169 50
PMI2630 YP_002152332.1 DNA topoisomerase III Not tested Not named Protein 4e-168 49