Gene Information

Name : Entcl_3878 (Entcl_3878)
Accession : YP_003943402.1
Strain : Enterobacter cloacae SCF1
Genome accession: NC_014618
Putative virulence/resistance : Unknown
Product : integrase family protein
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0582
EC number : -
Position : 4171010 - 4172257 bp
Length : 1248 bp
Strand : -
Note : PFAM: integrase family protein; KEGG: sbc:SbBS512_E4814 site-specific recombinase, phage integrase family protein

DNA sequence : 
ATGGCTCTGACAGATATCAAAGTGCGCTCTGCAAAACCACAGGAAAAGGAGTATACCCTTGTCGATGGGGATGGCATGTT
TTTGCTCATTCACCCTAACGGCTCAAAATACTGGCGGTTCCGCTTTCGCTTTGGTGGTAAGCAGCACCTGATGGCATTTG
GGGTTTATCCTGAAACGTCACTGGCTGATGCTCGTCAAAAAAGGGAAGAGGCCAGAAAGCTTGTTGCTGCAGGAATCGAT
CCTCGCGAACACAAACGTGCGGTGAAAGAACAACAGGCGAAAGAAAATATTACCTTTGAGTCAGTTGCCAGAGAGTGGCA
TGCCGCAAATAAAAAATGGTCAGAAGAACATAGCCGACGGGTGCTGAAGAGTCTGGAAGATAATTTGTTCCCAGCGATTG
GAAAGCGAAGTATTGATAGTTTTAGTACGCGCGATCTCCTTGTGCCTATCAAAGTAGTTGAGGCTACAGGGCGTCTTGAA
GTGGCTTCGCGTCTTCAGCAGCGTACCAATGCGATTATGCGTTATGCAGTGCAAAGCGGTTTGATCGATTACAATCCTGC
TCAGGAGATGGCTGGGGCAGTTGCTTCAAGTAATCGTGTCCATCGACCAGCACTTGAACTGAAACGCTTACCTGAACTAC
TCCACCGAATTGATAGCTACACCGGACGGCCTTTAACCCGTCTGGCTGTTGAGCTAACGTTATTAATTTTTATTCGTTCT
AGTGAATTGCGCTTTGCCCGTTGGTCCGAGATCGATTTTGAAAGGGCAATGTGGACGATCCCGGCAGAACGAGAAGCTAT
AGAAGATGTTAAGCATTCGCAACGTGGTTCTAAAATGCGCACACCTCACTTAGTGCCGCTGTCTCGTCAGGCATTGGCAA
TCCTTAAACAGGTTCACAAGCTTAGTGGCGAGCGCGATTTTGTTTTCATTGGCGATCATAATCCGCTTAAACCGATGAGT
GAAAACACGGTTAACAAGGCGCTGCGTGTTATGGGTTATGACACAAAGGTCGATGTTTGTGGGCATGGTTTCAGGGCTAT
GGCATGCAGCTCGTTGATTGAATCAGGTCTGTGGTCCAGGGACGCTGTTGAAAGGCAGATGAGCCATATGGAGCGTAACT
CTGTACGCGCTGCTTACATTCATAAGGCTGAGCATCTTGATGAGCGGCGACTAATGCTGCAGTGGTGGGCTGATTTATTG
GATGTGAATAGGGAAAGGGAAGTTAGTCCTTATGACTTTGGCAAGTAG

Protein sequence : 
MALTDIKVRSAKPQEKEYTLVDGDGMFLLIHPNGSKYWRFRFRFGGKQHLMAFGVYPETSLADARQKREEARKLVAAGID
PREHKRAVKEQQAKENITFESVAREWHAANKKWSEEHSRRVLKSLEDNLFPAIGKRSIDSFSTRDLLVPIKVVEATGRLE
VASRLQQRTNAIMRYAVQSGLIDYNPAQEMAGAVASSNRVHRPALELKRLPELLHRIDSYTGRPLTRLAVELTLLIFIRS
SELRFARWSEIDFERAMWTIPAEREAIEDVKHSQRGSKMRTPHLVPLSRQALAILKQVHKLSGERDFVFIGDHNPLKPMS
ENTVNKALRVMGYDTKVDVCGHGFRAMACSSLIESGLWSRDAVERQMSHMERNSVRAAYIHKAEHLDERRLMLQWWADLL
DVNREREVSPYDFGK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
intB CAD42017.1 bacteriophage P4 integrase Not tested PAI II 536 Protein 4e-149 76
ECO111_3718 YP_003236059.1 putative integrase Not tested LEE Protein 5e-142 67
SF2964 NP_708738.1 P4-type integrase Not tested SHI-1 Protein 8e-145 67
ORF_1 AAZ04412.1 phage integrase Not tested PAI I APEC-O1 Protein 8e-145 67
c5216 NP_757064.1 prophage P4 integrase Not tested PAI II CFT073 Protein 3e-144 67
APECO1_3534 YP_854214.1 P4-like integrase Not tested PAI I APEC-O1 Protein 1e-144 67
S4822 NP_838459.1 P4-type integrase Not tested SHI-1 Protein 8e-145 67
int AAK00456.1 Int Not tested SHI-1 Protein 1e-135 67
int ADD91747.1 P4 integrase Not tested PAI-I AL862 Protein 3e-144 67
int AAT48697.1 CP4-like integrase Not tested PAI I 4787 Protein 4e-143 67
Z4313 NP_289539.1 pathogenicity island integrase Not tested OI-122 Protein 1e-142 67
int AAL51003.1 CP4-like integrase Not tested LEE Protein 3e-143 67
c3556 NP_755431.1 prophage P4 integrase Not tested PAI I CFT073 Protein 7e-143 67
int-phe AAL57571.1 CP4-like integrase Not tested LEE Protein 2e-143 67
ECO103_3550 YP_003223418.1 integrase Not tested LEE Protein 2e-143 67
int AAL51028.1 CP4-like integrase Not tested LEE Protein 2e-143 67
ECO26_5300 YP_003232178.1 integrase Not tested LEE Protein 2e-143 67
int-phe AAL60261.1 Int-phe Not tested LEE Protein 2e-143 67
intP4 CAE85151.1 CP4 integrase protein Not tested PAI V 536 Protein 4e-144 67
int AAK16198.1 Int Not tested PAI-I AL862 Protein 3e-144 67
ECUMN_3322 YP_002414004.1 integrase Not tested Not named Protein 2e-141 67
int CAC81896.1 integrase Not tested LEE II Protein 2e-134 67
SESS1296_03598 AFO66301.1 bacteriophage integrase Not tested SESS LEE Protein 1e-128 62
SESS1635_03816 AFO66367.1 bacteriophage integrase Not tested SESS LEE Protein 1e-128 62
APECO1_1051 YP_853069.1 phage integrase Not tested PAI IV APEC-O1 Protein 1e-81 57
intB AAD37509.1 P4-like integrase Not tested PAI IV 536 Protein 2e-93 56
int YP_002346908.1 integrase Not tested HPI Protein 9e-110 55
y2393 NP_669700.1 prophage integrase Not tested HPI Protein 9e-110 55
int2 NP_993013.1 integrase Not tested HPI Protein 9e-110 55
int CAA08754.1 integrase Not tested HPI Protein 2e-110 55
int CAA21384.1 - Not tested HPI Protein 9e-110 55
int CAB59974.1 integrase Not tested HPI Protein 7e-111 55
STY4821 NP_458899.1 integrase Not tested SPI-10 Protein 5e-118 55
unnamed AAD17660.1 unknown Not tested HPI Protein 5e-107 54
int NP_458759.1 bacteriophage integrase Not tested SPI-7 Protein 1e-114 53
int NP_807963.1 bacteriophage integrase Not tested SPI-7 Protein 1e-114 53
unnamed ABR13507.1 phage integrase Not tested PAGI-6 Protein 4e-107 53
int AAD44730.1 Int Not tested SHI-2 Protein 3e-83 44
aec33 AAW51716.1 Int Not tested AGI-3 Protein 6e-84 44
int CAC39282.1 integrase Not tested LPA Protein 6e-84 44
ESA_03025 YP_001439090.1 hypothetical protein Not tested Not named Protein 2e-76 43
int AAC31482.1 CP4-like integrase Not tested LEE Protein 7e-82 43
int ACU09430.1 integrase Not tested LEE Protein 7e-82 43
intL NP_290239.1 integrase for prophage 933L and the LEE pathogenicity island Not tested LEE Protein 9e-82 43
ECs4534 NP_312561.1 integrase Not tested LEE Protein 9e-82 43
int AAD54663.1 Sai integrase Not tested SHI-2 Protein 7e-82 43
S4835 NP_839238.1 integrase Not tested SHI-2 Protein 9e-82 43
SF3698 NP_709437.1 integrase Not tested SHI-2 Protein 9e-82 43
unnamed AFX83955.1 integrase Not tested SE-PAI Protein 2e-73 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Entcl_3878 YP_003943402.1 integrase family protein VFG1536 Protein 2e-149 76
Entcl_3878 YP_003943402.1 integrase family protein VFG0626 Protein 3e-145 67
Entcl_3878 YP_003943402.1 integrase family protein VFG1693 Protein 3e-143 67
Entcl_3878 YP_003943402.1 integrase family protein VFG0783 Protein 4e-82 43
Entcl_3878 YP_003943402.1 integrase family protein VFG0598 Protein 4e-82 43