Gene Information

Name : clpB (BBIF_0307)
Accession : YP_003938086.1
Strain : Bifidobacterium bifidum S17
Genome accession: NC_014616
Putative virulence/resistance : Virulence
Product : ATP-binding subunit of Clp protease
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 367123 - 369786 bp
Length : 2664 bp
Strand : +
Note : -

DNA sequence :
ATGGAACAGAAGTTCACCACCATGGCCCAGGAAGTCATCGGTGATGCGATTCAGAGCGCGTCTGCCGCGGGCAACGCGCA
GGTCGAGACACTGCACGTGATGGATGCGCTGCTGCGTCAGGAAAACGGCGTGATTCAGGGACTGATTCAGGCGGCGGGCG
GCAACCCGCAGGCGATTGGCGCCGCGGTGCGCAATGCTCTGGTCAAGATGCCGGCGGCGAGCGGGTCCACCACATCGCAG
CCGCAGGCGAGCCGCCAGCTGACGGCGGCGCTGGCACAGGCCGAGAAGGAGATGCAGCAGATGGGCGACGAGTACGTCTC
CACCGAGCACCTGCTCATCGGCATCGCCGCATCCGCGCCGAACCAGAGCGCGGACATCCTCAAGGCGAACGGCGTGACGG
CCGCGGCGCTGCGCAAGGCCGTCCCCGGCGTGCGCGGCGGCGCCAAGGTCACCAGCCCGGACGCTGAGGGCAGCTACAAG
GCGTTGGAGAAGTACTCCACCGATCTGACCGCCCGCGCCAAGGAGGGTAAGCTCGACCCGGTGATCGGGCGTGATCAGGA
GATCCGCCGTGTGATCCAGATCCTGAGCCGCCGCACCAAGAACAACCCGGTGCTGATCGGCGAGCCCGGCGTCGGCAAGA
CCGCCGTCGTGGAGGGCCTCGCCCAGCGTATCGTGGCCGGCGATGTGCCGACCACGCTGCAGAACAAAAAGCTCATCAGC
CTCGATTTGGGGTCGATGGTTGCCGGCTCGAAGTACCGTGGCGAGTTCGAGGAGCGCCTCAAGAGCGTGCTCAACGAAAT
CAAGAACGCCGACGGCCAGATCATCACGTTCATCGACGAGATTCATACGATCGTCGGCGCTGGCGCGGCCGAAGGCTCGA
TGGATGCCGGCAACATGCTCAAGCCCATGCTGGCGCGCGGCGAGCTTCGCCTGATCGGCGCGACCACGCTGGACGAGTAC
CGCGAGAACATCGAGAAGGACCCGGCGCTTGAGCGTCGTTTCCAGCAGGTGTTCGTGGGCGAGCCGAGCGTGGAGGACAC
GATCGCGATTCTGCGTGGCCTGAAGCAGCGTTACGAGGCGCACCACAAGGTGACGATCGGCGACGACGCGCTGGTCGCCG
CCGCGACGCTCTCGAACCGCTATATTTCCGGCCGTCAGCTGCCCGACAAGGCCATCGATCTGGTCGATGAGGCGGCCGCG
CACCTGCGCATGGAGCTCGACTCCTCCCCGGAGGAGATCGACGAACTGCAGCGCAAGGTCACGCGCTACGAGATGGAGGA
GATGCAGCTCAAGAAGGCCGAGGATCCAGCCAGCAAGGAGCGCTTGGAGAAGCTGCAGAACGAGCTCGCGAACACTCGCG
AGAAGCTGAGCGGCCTCAAGGCCCGCTGGGATGCGGAGAAGGCCGGCCACAACAAGGTCGGCGACCTGCGCGCCCAGCTG
GACGCCAAGCGCGTCGAGGCTGACAAGTTCACCCGTGAGGGCAACTTGGCCGAGGCGTCGAAGATCCTGTACGGCGAGAT
TCCGGCGATTCAGAAGCAGCTGGACGCGGCCGAGAAGGCCGATGCGGAAGACGGCGCGACGGGCGAGATCAAGCCCGAGC
CGATGGTGCCCGACCATGTGGACGCCGATTCGGTGGCCGGCATCGTCTCCGAGTGGACCGGCATCCCCGTCGGTCGCCTG
ATGCAGGGCGAGAACGAGAAGCTGCTGAGCATGGAGGACTACCTCGGCAAGCGCGTGATCGGCCAGAAGGAAGCGATCGC
GGCGGTGAGCGACGCGGTGCGTCGTTCACGCGCCGGCATCAGCGACCCGAACCGTCCGACCGGCTCGTTCCTGTTCCTCG
GCCCCACCGGCGTGGGCAAGACCGAGCTCGCCAAGGCGCTCGCCGACTTCCTGTTCGACGACGAGAAGGCCATGGTCCGC
ATCGATATGTCGGAGTACATGGAGAAGGCGTCTGTGAGCCGTCTGATCGGCGCCGCGCCCGGCTACATCGGCTATGAGGA
AGGCGGCCAGCTGACCGAGGCCGTGCGTCGTCGTCCGTACTCGGTGGTGCTGTTCGACGAAGTCGAGAAAGCTAACCCCG
AAGTCTTCGACGTGCTGCTGCAGGTGCTGGACGACGGGCGTCTGACCGACGGCCAAGGCCGGACTGTGGACTTCAAGAAC
ACGATCCTGATCATGACCTCGAACCTCGGCTCGCAGTTCCTGGTGAACCAGGACATGGACGCGGACGCCAAGAAGAAGGC
CGTGATGGACGCGGTGCACATGAACTTCAAGCCGGAGTTCCTGAACCGTCTGGACGAGATCGTGATGTTCCATCCGCTGA
CCCGTGAGGAGCTGGGCGGCATCGTCAACATCCAGGTCGCTCAGGTGGCCTCGCGTCTGACGGATCGCCGCATCAAGCTC
GACGTCACCGACGCGGCTCGCGAATGGCTCGCCAACACCGGCTATGACCCGGCGTACGGCGCTCGTCCGCTGCGCCGTCT
GGTGCAGACCGAGGTCGGCGACCAGCTGGCGCGCATGCTGCTCGCCGGCAAGGTACACGACGGCGACACCGTGCTCGTCG
ACCAGACCGGTGGCGAGCATCTGGAACTCGGTACCATGCCCGAGGATCCGGATGCCGGATCCGATACCGACGTCACGGTC
GAAGACGTCACCGAAGACAAGTGA

Protein sequence :
MEQKFTTMAQEVIGDAIQSASAAGNAQVETLHVMDALLRQENGVIQGLIQAAGGNPQAIGAAVRNALVKMPAASGSTTSQ
PQASRQLTAALAQAEKEMQQMGDEYVSTEHLLIGIAASAPNQSADILKANGVTAAALRKAVPGVRGGAKVTSPDAEGSYK
ALEKYSTDLTARAKEGKLDPVIGRDQEIRRVIQILSRRTKNNPVLIGEPGVGKTAVVEGLAQRIVAGDVPTTLQNKKLIS
LDLGSMVAGSKYRGEFEERLKSVLNEIKNADGQIITFIDEIHTIVGAGAAEGSMDAGNMLKPMLARGELRLIGATTLDEY
RENIEKDPALERRFQQVFVGEPSVEDTIAILRGLKQRYEAHHKVTIGDDALVAAATLSNRYISGRQLPDKAIDLVDEAAA
HLRMELDSSPEEIDELQRKVTRYEMEEMQLKKAEDPASKERLEKLQNELANTREKLSGLKARWDAEKAGHNKVGDLRAQL
DAKRVEADKFTREGNLAEASKILYGEIPAIQKQLDAAEKADAEDGATGEIKPEPMVPDHVDADSVAGIVSEWTGIPVGRL
MQGENEKLLSMEDYLGKRVIGQKEAIAAVSDAVRRSRAGISDPNRPTGSFLFLGPTGVGKTELAKALADFLFDDEKAMVR
IDMSEYMEKASVSRLIGAAPGYIGYEEGGQLTEAVRRRPYSVVLFDEVEKANPEVFDVLLQVLDDGRLTDGQGRTVDFKN
TILIMTSNLGSQFLVNQDMDADAKKKAVMDAVHMNFKPEFLNRLDEIVMFHPLTREELGGIVNIQVAQVASRLTDRRIKL
DVTDAAREWLANTGYDPAYGARPLRRLVQTEVGDQLARMLLAGKVHDGDTVLVDQTGGEHLELGTMPEDPDAGSDTDVTV
EDVTEDK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 2e-102 41
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 7e-106 41
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 5e-106 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpB YP_003938086.1 ATP-binding subunit of Clp protease VFG2076 Protein 4e-117 42
clpB YP_003938086.1 ATP-binding subunit of Clp protease VFG2084 Protein 8e-110 42