Gene Information

Name : lysU (CLOST_0952)
Accession : YP_003935982.1
Strain : Clostridium sticklandii DSM 519
Genome accession: NC_014614
Putative virulence/resistance : Virulence
Product : lysine tRNA synthetase, inducible
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : 6.1.1.6
Position : 1088476 - 1089996 bp
Length : 1521 bp
Strand : +
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10913247, 2183178, 2188953, 7735833, 90264318, 91161511, 95020522; Product type e : enzyme

DNA sequence :
ATGTCTAATGATCAAATGAATTCTGAAACGCTAAGTTTGAACGAGATGCTTCAAATAAGAAGGGACAAGCTGAAGAAGCT
TCAAGAAGCTGGTAAAAACCCTTTTAAGATAGAGAAATACATAAAGACTCATCACAGCAAGCAAGTTAAGGACAACTTTG
AAAAGTTAGAGGGAAGCGAAGTTTCTCTTGCAGGAAGAATTATGAGTATGAGAGGACATGGCAAGGCTTCTTTTATTGAT
ATCCAAGATGAACAAGGAAGAATACAGGTTTATGTAAGACAAGATGCTATAGGTGATGATAGCTACACAGATTTTGTTAC
TTATGATATGGGAGACATTATTGGTGTAGAAGGTACAGTGTTTATGACCAATAAAGGGGAGCAATCAGTAAAAGCATCTA
AGGTTGCATTACTTACTAAATCTCTTCAAATTTTACCTGAAAAATATCATGGATTAAAAGATCCTGATTTAAGATATAGA
CAAAGATATGTGGATTTAATCGTGAATCCAGATGTAAAAGAGGCTTTCTTGATAAGAAGTAAAGCAATAAAGGCATTAAA
AGAATATCTAGATGAAAGAGATTTCCTAGAGGTAGATACTCCTATACTATCTACTATAGCAGGAGGAGCAACAGCAAGAC
CTTTCATCACTCATCATAATACTCTAGATATTGATATGTATATGCGTATTGCAAATGAGCTATACTTAAAAAGACTTATT
GTGGGTGGGTTTGAAAGAGTATATGAGCTAGGAAAAATGTTTAGGAATGAAGGTATGTCAATCAAGCACAACCCTGAGTA
TACAGCTATAGAGGTATATCAGGCTTATGCTGATTATGAAGATATAATGAGACTTACTGAAGAAGCTGTAGCTTGCATGG
CGCAAAAATCACTTGGAACTACAAAAATAAATTATCAAGGTACAGAAATCGATCTTACTCCTCCGTGGAGAAGACTTAGC
ATGATTGATGCAATAAAAGAATTTAAAGGTATAGACTTTAATGAAATTCAAACGGATGAAGAAGCCATTAAAGTTGCAAA
AGAAAATCACATTGAAATTACTCCAGTTATGAATAGAGGCTTTGTTATAGCTGCGATGTTTGAAGAGTTCTGTGAGGAGC
ATTTAATTCAGCCTACATTTATAACTCATCATCCAGTTGAGGTTTCTCCGCTATCTAAGAGAAATCCAGATGACCCAAGA
CTTACAAATAGATTCGAGGCATTTGTAAACACTTGGGAAATTGCAAATGCTTTCTCAGAGCTAAATGATCCTATCGACCA
AAGAGAAAGATTTATGGATCAATTGAAGCAAAGAGAGCTAGGAGACGATGAAGCCTATATGCTTGATGAAGACTTCTTAA
ATGCAATAGAAGTAGGACTTCCACCAACAGGCGGTCTTGGAATAGGTATTGATAGAGTTATAATGTTACTTACTAACTCG
TCATCTATCAGAGATGTAATACTTTTTCCTACAATGAAGCCTATAAAAGAAGAAAAGAATGACGCTAAAGAACAAAACTA
A

Protein sequence :
MSNDQMNSETLSLNEMLQIRRDKLKKLQEAGKNPFKIEKYIKTHHSKQVKDNFEKLEGSEVSLAGRIMSMRGHGKASFID
IQDEQGRIQVYVRQDAIGDDSYTDFVTYDMGDIIGVEGTVFMTNKGEQSVKASKVALLTKSLQILPEKYHGLKDPDLRYR
QRYVDLIVNPDVKEAFLIRSKAIKALKEYLDERDFLEVDTPILSTIAGGATARPFITHHNTLDIDMYMRIANELYLKRLI
VGGFERVYELGKMFRNEGMSIKHNPEYTAIEVYQAYADYEDIMRLTEEAVACMAQKSLGTTKINYQGTEIDLTPPWRRLS
MIDAIKEFKGIDFNEIQTDEEAIKVAKENHIEITPVMNRGFVIAAMFEEFCEEHLIQPTFITHHPVEVSPLSKRNPDDPR
LTNRFEAFVNTWEIANAFSELNDPIDQRERFMDQLKQRELGDDEAYMLDEDFLNAIEVGLPPTGGLGIGIDRVIMLLTNS
SSIRDVILFPTMKPIKEEKNDAKEQN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 1e-105 47

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysU YP_003935982.1 lysine tRNA synthetase, inducible VFG1668 Protein 7e-106 47