Gene Information

Name : yveM (CLOST_0401)
Accession : YP_003935436.1
Strain : Clostridium sticklandii DSM 519
Genome accession: NC_014614
Putative virulence/resistance : Virulence
Product : putative capsular polysaccharide biosynthesis protein YveM
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1086
EC number : -
Position : 467487 - 469358 bp
Length : 1872 bp
Strand : +
Note : Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology

DNA sequence :
ATGAGGGAGATTTTATCAAATAAATTAATAAGAAAACTAGTACTTCTATTTGCAGATGCTGCACTGGTAAATCTAGCTGC
ACTACTTGCCTTAGAGATTAGGTTTGATTTTTATATTACAGGAAGCAATATAGAATATAAAATTGCTTTTATAGATCATT
TTGTTATATATACGGGTATTGTGTTGGTGATTTTTTACTTATTTGGACTTTATAGAAGTTTATGGAGATATGCAAGCATT
AATGAAATGATGTCGATTGCACTAGCTGCTTTGTGGTCTAATATAGCAACATATATTACTTTTTTACTGCTTGATGTAAA
TATGCCTAGAAGCTTTTATATAATAAATATGTTTACTATGGCTGCGTTTGTTGGTGGGCTTAGGTTTTCATATAGAGTGC
TTAGACGTATAGAAATGGGAAAGCTACAGACTAATAAACTAAATAGGCCTCTGTCAAAGGTACTTATTATAGGAGCGGGA
GAAGCAGGAGTTATGACTGCTAAAGAACTTCTTAGGACTCCAGATATGAATAAGGTTTTAGTTGGATTTGTAGATGACGA
TTCAAATAAAATAGGGAAAAAAATAAATGGGATTCCTATTGTAGCTGATATAAGCTCAGGAGTAAAATTTTTAGATGATG
TAGATGAGATTATTTTAGCGATGCCTTCTATTACTCATAAGAGAAGAAAAGAAATTATAGAAATATATAAAGACTCTGGT
GTGAAAATGAAGATTCTTCCAGGGATATACGAGCTTATAGACGGACAAGTAGATATCAAAAAAATCAGAGACGTGGATAT
TGAGGATCTACTAGGAAGAGATTCTATAGCTCTTGATAATACTAAAATAGCAGAAGATATAAAAAACAAAATAGTTATAG
TAACTGGAGGGGGAGGCTCTATAGGCTCGGAGCTATGTAGACAGATAGCAGGTTTTTCACCAAAATTACTTATTATATTT
GATATATATGAAAACTCAGTATATGATATTCAAAACGAGCTTAAGTCTAAATATCCTACACTTCCCCTAAAAGTGCTTAT
AGGCTCTGTAAGGGATGTAAATAGACTAGATGAGATTTTTTTGAAATACAGGCCACAGCTAGTATTTCATGCGGCAGCTC
ATAAGCATGTACCACTTATGGAAGATAGCCCTTTTGAAGCTATCAAGAACAATACAGTAGGAACTAAGAATATTTCTGAA
ATAGCTGGGAAATATGAAGTTCAAAGATTTGTGCTAATTTCAACTGATAAAGCTGTCAACCCTACAAATATTATGGGAGC
TAGTAAAAGACTTGCTGAGCTAGTCATTCAAGATATGAACAAGAAATATTCAACTGAGTATGTAGCAGTTAGATTTGGAA
ATGTTCTAGGAAGCAATGGAAGTGTTATTCCGTTATTTAAAAAGCAGATTGAAAAAGGTGGACCTATTACTGTAACTCAT
CCTGACATCATAAGATATTTTATGACTATTCCAGAAGCAGTTCAATTAGTGCTTCAAGCGGGCTCTATGGCCAAGGGTGG
AGAAATATTTATTCTGGATATGGGAGAGCCTGTTAAAATAGTTGATTTAGCAGAGGATTTAATTAGGCTGTCTGGATTTG
AGCCTTATGAGGATATAAATATAGAATTTACTGGGCTTAGACCAGGAGAAAAATTATTTGAAGAGCTACTCCTTGCAGAA
GAAGGCATATTAGATACCAAACATGAAAAGATTTTTGTAGGAAAGCCATTTGATAAGGATGATGACTTCACTAGAAAAAG
TTTAGAGGGAATTATAGAATCTACATTCGAAGGAAACTATTCTCAGCTAGAGCAAAGAATTAAATTTTTAATACCAAGCT
ATAGAGATAAATTAGAACAGAAAAAAGCTTAA

Protein sequence :
MREILSNKLIRKLVLLFADAALVNLAALLALEIRFDFYITGSNIEYKIAFIDHFVIYTGIVLVIFYLFGLYRSLWRYASI
NEMMSIALAALWSNIATYITFLLLDVNMPRSFYIINMFTMAAFVGGLRFSYRVLRRIEMGKLQTNKLNRPLSKVLIIGAG
EAGVMTAKELLRTPDMNKVLVGFVDDDSNKIGKKINGIPIVADISSGVKFLDDVDEIILAMPSITHKRRKEIIEIYKDSG
VKMKILPGIYELIDGQVDIKKIRDVDIEDLLGRDSIALDNTKIAEDIKNKIVIVTGGGGSIGSELCRQIAGFSPKLLIIF
DIYENSVYDIQNELKSKYPTLPLKVLIGSVRDVNRLDEIFLKYRPQLVFHAAAHKHVPLMEDSPFEAIKNNTVGTKNISE
IAGKYEVQRFVLISTDKAVNPTNIMGASKRLAELVIQDMNKKYSTEYVAVRFGNVLGSNGSVIPLFKKQIEKGGPITVTH
PDIIRYFMTIPEAVQLVLQAGSMAKGGEIFILDMGEPVKIVDLAEDLIRLSGFEPYEDINIEFTGLRPGEKLFEELLLAE
EGILDTKHEKIFVGKPFDKDDDFTRKSLEGIIESTFEGNYSQLEQRIKFLIPSYRDKLEQKKA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cap1D AAA64643.1 type 1 capsule synthesis gene Virulence SCCcap1 Protein 2e-87 46
SSP0063 YP_300153.1 capsular polysaccharide biosynthesis protein Not tested SCC15305cap Protein 6e-88 46

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
yveM YP_003935436.1 putative capsular polysaccharide biosynthesis protein YveM VFG1300 Protein 3e-83 45