Gene Information

Name : guaA (CLOST_0297)
Accession : YP_003935332.1
Strain : Clostridium sticklandii DSM 519
Genome accession: NC_014614
Putative virulence/resistance : Unknown
Product : GMP synthetase (glutamine aminotransferase)
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 342302 - 343831 bp
Length : 1530 bp
Strand : +
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2982857, 3894345, 85261223, 8548458; Product type e : enzyme

DNA sequence :
ATGAAACACGAAACAGTACTAATAATAGATTTTGGTGGACAGTACAATCAGCTTATAGCAAGAAGAGTTAGAGAAGCAAA
AGTATACTGCGAAATCGTACCTTACAAAAAAGCAATGGAAAAAATAAAGGAAGTTAAGCCAGAAGGAATCATATTTACAG
GAGGACCATCAAGTGTAAATGATCCTGGAGCTCCAGATATTCAGGCAGAAATATTTGACCTAGGCATTCCTATACTTGGA
ATCTGCTATGGGGCACAGCTTACAGCTAAAACTCTTGGAGGAAGTGTAGCAAAACCAGAAAAAAGAGAATACGGAAAAAC
AGAGATAAACTATACGGGTGGAAAATTATTTAAAGATGTTGATAAATCAAACATCTGCTGGATGAGTCACACAGACCAAA
TAGATAAGCTTCCAGAAGGCTTCACGATTACAGCGGCTACACATGACTGTCCAGTAGCGGCAATGGAAAATGTAGACAAA
AAACTATATGCGCTTCAGTTTCATCCAGAAGTAGAGCATACAGTGCAAGGCTACAAAATAATTCGTAATTTCCTATTTGA
AGTATGCGCTTTGTCTGGCGATTTTACTTCAGACTCCTTCATAGATGATAAAGTAAGGCTCATAAGACAGCAGGTGGGAG
ATAAAAAAACCCTTTGTGCCCTTAGTGGAGGGGTGGATTCCTCTGTGGCAGCAGTTCTCGTACATAAAGCCATAGGGGAT
AACCTCACCTGTATATTCGTAGACCATGGTCTACTTAGAAAAAATGAAGGTGACGATGTAGAGAGAATATTCAGAGACGA
ATTCTCTATGAATCTAATCAGAGTGAATGCTCAGGAAAGATTCCTTTCAAAGCTAGCTGGGGTAACTGACCCAGAAAGAA
AAAGAAAAATTATTGGAGAAGAATTCATAAGAGTATTTGAAGAGGAGTCTAAAAAGCTAGGGGATGTAGAGTTCCTAGTA
CAAGGCACTATCTACCCAGACGTAATAGAAAGTGGAACAGATGAAGCGGCTGTAATCAAGAGTCACCACAATGTTGGAGG
ACTTCCTGAAGACATGAAGCTGAGCCTAGTTGAGCCACTTAGAGAGCTTTTCAAAGACGAAGTTAGAAATGTTGGACTAG
AGCTAGGAATTCCTGAATACCTTATATTTAGACATCCATTCCCAGGACCAGGACTAGGAATCAGAGTACTAGGAGAAGTA
ACTGAGGAAAAATGCGACATATTAAGAGAAGCTGATGCTATCTATAGAGAAGAACTAGAAAAAGCAGGACTAGGAAGAAA
AATCTGGCAAGCATTTGCAACACTTCCAGATGTAAAAACCGTAGGAGTAATGGGAGATGAGCGTACCTACTCATATATGG
TAGGCCTAAGAGCAATCACCTCAACTGATGGAATGACAGGAGAATTTTATCCTATCCCATATGAAGTGCTAGGAACCATA
TCAACTAGAATAGTAAACGAAGTAAAAGGCGTAAATAGAGTAGTCTATGATGTAACAGGAAAACCACCAGCGACAATTGA
GTGGGAATAG

Protein sequence :
MKHETVLIIDFGGQYNQLIARRVREAKVYCEIVPYKKAMEKIKEVKPEGIIFTGGPSSVNDPGAPDIQAEIFDLGIPILG
ICYGAQLTAKTLGGSVAKPEKREYGKTEINYTGGKLFKDVDKSNICWMSHTDQIDKLPEGFTITAATHDCPVAAMENVDK
KLYALQFHPEVEHTVQGYKIIRNFLFEVCALSGDFTSDSFIDDKVRLIRQQVGDKKTLCALSGGVDSSVAAVLVHKAIGD
NLTCIFVDHGLLRKNEGDDVERIFRDEFSMNLIRVNAQERFLSKLAGVTDPERKRKIIGEEFIRVFEEESKKLGDVEFLV
QGTIYPDVIESGTDEAAVIKSHHNVGGLPEDMKLSLVEPLRELFKDEVRNVGLELGIPEYLIFRHPFPGPGLGIRVLGEV
TEEKCDILREADAIYREELEKAGLGRKIWQAFATLPDVKTVGVMGDERTYSYMVGLRAITSTDGMTGEFYPIPYEVLGTI
STRIVNEVKGVNRVVYDVTGKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-151 59
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 2e-151 59
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 2e-151 59
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-136 53