Gene Information

Name : fepC (CLOST_2465)
Accession : YP_003937485.1
Strain : Clostridium sticklandii DSM 519
Genome accession: NC_014614
Putative virulence/resistance : Virulence
Product : iron-enterobactin transporter subunit ; ATP-binding component of ABC superfamily
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG1120
EC number : -
Position : 2598935 - 2599780 bp
Length : 846 bp
Strand : -
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 87279914, 92157868; Product type t : transporter

DNA sequence : 
ATGTCAAGGCTATACACAGAGGGAATCAATATAGGCTATGATGATAATTTGATTGTTAAGAATTTAAGTATTGAGATTCC
AGATAAAAAAATAACTACAATTATTGGCTCAAACGGATGCGGAAAATCTACATTGCTAAAAGCCATTACTAGAATAATTT
CTCATAAGTCAGGAACTGTTGTTTTAGACGGCAAGGATATTTTAAAGGAAAATACTAGAGAGCTTGCCAAGAAAATGGCC
ATCCTTCCTCAAACGCCTGAAGCCACTATAGGACTCACAGTAGGAGAGCTTGTGTCCTATGGAAGATTTCCATATCAAAA
TGGGCTTGGCAGATTGACAAAAAAGGATTTTGAAGTAATAGACTGGGCACTTGAGGTTACGGGAACAAAGCAGTATAAAT
TTCGTACGATAGATGCTCTATCGGGAGGTCAAAGGCAAAGAGTCTGGATAGCAATGGCACTGGCTCAAGAAACAGATATA
ATTTTTCTCGATGAACCTACGACTTACTTGGATATGGCTCACCAGTTAGAAGTGCTTGAGCTTTTAAAGAAGCTAAACTT
AGAGCAAGAAAGAACTATAGTCATGGTTCTTCATGATATCAATCAAGCTGCCAGATTTGCAGACTACATAATTGCATTAA
AAGATGGTCAAATAGTAAAAGCAGGGGACTGTGAAGAAGTGATTACTAAAGAGGTGCTTAAAAAGGTTTATAATATCAGC
GCTGAGATTGGAAGAGATTCATTTACAAATAAACCTATATGCATTACATATAATTTACTAAAAGGAGAGACAGAAGATGA
AGAAATTATTGATACCTATGATACTGGTATTTGCGTTAATTTTTAG

Protein sequence : 
MSRLYTEGINIGYDDNLIVKNLSIEIPDKKITTIIGSNGCGKSTLLKAITRIISHKSGTVVLDGKDILKENTRELAKKMA
ILPQTPEATIGLTVGELVSYGRFPYQNGLGRLTKKDFEVIDWALEVTGTKQYKFRTIDALSGGQRQRVWIAMALAQETDI
IFLDEPTTYLDMAHQLEVLELLKKLNLEQERTIVMVLHDINQAARFADYIIALKDGQIVKAGDCEEVITKEVLKKVYNIS
AEIGRDSFTNKPICITYNLLKGETEDEEIIDTYDTGICVNF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
iusE YP_005143742.1 iron ABC transporter ATP-binding protein Virulence Not named Protein 2e-50 47
SPN23F_09560 YP_002510939.1 ferric siderophore ABC transporter ATP-binding protein Virulence PPI-1 Protein 7e-51 47
SP_1035 NP_345510.1 iron-compound ABC transporter ATP-binding protein Not tested PPI-1 Protein 7e-51 47
fagC YP_005684488.1 ATP binding cytoplasmic membrane protein Not tested PiCp 1 Protein 8e-47 46
fagC YP_005680307.1 ATP binding cytoplasmic membrane protein Not tested PiCp 1 Protein 7e-47 46
fagC YP_003782430.1 ABC transporter ATP-binding protein Not tested PiCp 1 Protein 7e-47 46
fagC YP_005682397.1 ATP binding cytoplasmic membrane protein Virulence PiCp 1 Protein 8e-47 46
DIP0585 NP_938961.1 iron ABC transporter ATP-binding protein Virulence Not named Protein 1e-46 42
ciuD YP_005681255.1 Iron ABC transporter ATP-binding protein Virulence PiCp 4 Protein 4e-46 42
ciuD YP_005683346.1 Iron ABC transporter ATP-binding protein Virulence PiCp 4 Protein 4e-46 42
ciuD YP_003783391.1 iron ABC transporter ATP-binding protein Virulence PiCp 4 Protein 4e-46 42
ciuD YP_005685432.1 Iron ABC transporter ATP-binding protein Virulence PiCp 4 Protein 4e-46 42
fecE AAL08451.1 ATP-binding protein FecE Virulence SRL Protein 6e-44 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
fepC YP_003937485.1 iron-enterobactin transporter subunit ; ATP-binding component of ABC superfamily BAC0164 Protein 4e-44 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
fepC YP_003937485.1 iron-enterobactin transporter subunit ; ATP-binding component of ABC superfamily VFG0925 Protein 1e-43 43
fepC YP_003937485.1 iron-enterobactin transporter subunit ; ATP-binding component of ABC superfamily VFG1042 Protein 3e-44 41