Gene Information

Name : tktB (CLOST_1766)
Accession : YP_003936791.1
Strain : Clostridium sticklandii DSM 519
Genome accession: NC_014614
Putative virulence/resistance : Unknown
Product : transketolase 2, thiamin-binding
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 1893002 - 1894987 bp
Length : 1986 bp
Strand : -
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8396116, 93374831; Product type e : enzyme

DNA sequence :
GTGAAAAAAATCGATGAAAGAGCTATAAACTCGATAAGATTTTTATCTATCGATAGCATCAATAAAGCTAACTCTGGCCA
TCCTGGATTACCAATGGGTGCAGCACCAATGGCATATACACTATGGAGCAAATTTTTAAGAATTTCTCCTCAGAATCCTA
CATGGGAAAATAGAGATAGATTCGTACTATCGGCTGGGCACGGCTCAATGCTTCTTTATTCACTACTTCATCTATTTAAC
TATGGATTACCTTTAGAAGAGCTTAAAAACTTTAGACAATTTGATAGCAAGACTCCAGGGCATCCTGAATATGGTCATAC
TGTAGGCGTGGAAACTACTACAGGACCACTAGGGCAAGGCTTTGCAAATGCGGTGGGTATGGCTATAGCAGAAAGACATT
TAGCTGGAAAGTTTAATACATCTAAATTTGACATAGTAGATCACTATACCTATGTACTTGCTGGGGACGGCGATATGATG
GAAGGAATCACATATGAAGCAGCATCACTTGCAGGAACGCTTAAGCTAGATAAGCTAGTTGCTCTTTATGATGATAATAA
AATTACTATAGATGGAAGTACTGATATTTCTTTTAGCGAAGATGTAAAAAAGAGATTTGAGGCAATGCACTGGAATGTTA
TCGTAGTTAAGGACGGTAATGATGCTGGTCTTATAAGAAAAGCTATAATAAAGGCTCATAAGTCAAAAGGCAAGCCTACA
CTTATTATGGTTAAGACCATAATAGGCTTTGGAAGTCCTAATAAAGCAGGTACTTCTAAAGTTCATGGTTCTCCACTTGG
CAAGGACGAAGCTATGCTAACAAGAGAGGCTCTTGGATGGAATGATTATAGCGAGTTTGAAATCCCTGAAGATGTAAAAG
ACCACTTTATGAGACTTAGCAAGAAAAAAGAAAAGACTTTTAAAGAGTGGCAGTCAAAGCTTGTGGATTATGCAAAGGAA
AATCCAGAGCTTTATAGAGAATGGAAAAGATATAATAGCAATGAGATTTCTAAGGAATTGTATGAAGACAAATCTATATT
TGAAACTTCTAGTGATAGTATGGCTACTAGAGCTTCAGGTGGAGATATACTAAATAAAATCGCAAAATATGTTCCAAATA
TAGTAGGAGGGTCAGCTGACCTAAATGAATCTACAAAGACTTATCTTAAAGAAAAAGGTGATTTTTTAGTAGATGATATG
GGAGCAAATATATTCTTTGGTATCAGAGAACATGCCATGGGAGCTATAGTAAACGGTATAGTACTTCACGGAGGACTAAG
AGCTTATGGTTCTACTTTCCTTGTTTTCTCTGATTATATGAGAACACCTATTAGACTGGCTTCTCTTATGAATATACCGG
CTATGTTTATTTTCACTCATGATTCAATAGGAGTAGGAGAAGATGGACCGACTCATCAGCCTATAGAGCACGTTTCAAGC
TTAAGAATGATGCCAGGACTTAGCGTGTGGAGACCAGCAGATTACATGGAGACAGGTTTTTCATATGTTGCGGCATTTGA
AAAAACTGATGGTCCAAGCGTTATGGTTCTAACAAGACAAAACCTTCCAAAGCTAGATGGAGTAAATGAAAATGTTAAGA
AGGGTGGATACATCCTATCTAAAGAAGAAAAAGCTACTCCTGATGCAATTCTTATGGGTTCTGGCTCTGAGGTTTCATTA
CTAGTTGAAGCTAAAAAAGTATTAAAAGAAAAAGGTCTGGATGTAAGAATAGTATCAATGCCAAACATGAATGTGTTTGA
AATGCAATCTAAAGAATATAAAGAAGAGGTACTTCCTAGCGATGTAGAAGCGAGAGTATCTGTAGAAGCTGGAGTTACTA
TGCCATGGTATAGATACCTAGGGAATAAAGGAACAGCAATAGGAATAGATACCTTTGGGGCTTCTGCTCCTATAGAAAAA
TTAATGAAGCATTTTGGTTTTAGTGTTGACAACGTAGTAGATAAAGTTCTTGAGGTAGTTAAATAG

Protein sequence :
MKKIDERAINSIRFLSIDSINKANSGHPGLPMGAAPMAYTLWSKFLRISPQNPTWENRDRFVLSAGHGSMLLYSLLHLFN
YGLPLEELKNFRQFDSKTPGHPEYGHTVGVETTTGPLGQGFANAVGMAIAERHLAGKFNTSKFDIVDHYTYVLAGDGDMM
EGITYEAASLAGTLKLDKLVALYDDNKITIDGSTDISFSEDVKKRFEAMHWNVIVVKDGNDAGLIRKAIIKAHKSKGKPT
LIMVKTIIGFGSPNKAGTSKVHGSPLGKDEAMLTREALGWNDYSEFEIPEDVKDHFMRLSKKKEKTFKEWQSKLVDYAKE
NPELYREWKRYNSNEISKELYEDKSIFETSSDSMATRASGGDILNKIAKYVPNIVGGSADLNESTKTYLKEKGDFLVDDM
GANIFFGIREHAMGAIVNGIVLHGGLRAYGSTFLVFSDYMRTPIRLASLMNIPAMFIFTHDSIGVGEDGPTHQPIEHVSS
LRMMPGLSVWRPADYMETGFSYVAAFEKTDGPSVMVLTRQNLPKLDGVNENVKKGGYILSKEEKATPDAILMGSGSEVSL
LVEAKKVLKEKGLDVRIVSMPNMNVFEMQSKEYKEEVLPSDVEARVSVEAGVTMPWYRYLGNKGTAIGIDTFGASAPIEK
LMKHFGFSVDNVVDKVLEVVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 5e-152 50
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 4e-141 48