Gene Information

Name : fliI (CLOST_1738)
Accession : YP_003936763.1
Strain : Clostridium sticklandii DSM 519
Genome accession: NC_014614
Putative virulence/resistance : Virulence
Product : flagellum-specific ATP synthase
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : 3.6.3.14
Position : 1866552 - 1867862 bp
Length : 1311 bp
Strand : -
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1482109; Product type e : enzyme

DNA sequence :
ATGATTGTAAACCTAAAAAAATATCATGATAGGCTAAACGAGATATCCTTATATCAATATAAAGGAAAGGTATCTAGAGT
TATAGGACTTACTATCGAATCGAGAGGCCCAGCGGTTAGGCTTGGAGAAACTTGCCATATATATCCTATAAAATCAAAAG
AGCCTGTATTAGCAGAGGTTGTAGGGTTTAAAGAAGACACTGTTCTTTTGATGCCACTTGGCGAAATGGAAGGGATAGGG
CCTGGCTCGATGGTGGTTGCAACTGGGAATACTCTAGAAGTAGATGTTGGAGAACAGCTGCTCGGAAGAATACTTGATGG
AATGGGAAATCCTATAGATGATTTTGAACCTCCATCACTTAATTATTCATATCCAGTAAATAACCAACCACCAAATCCGC
TTTCTAGAACGAAAATATCCGAACCATTACCTCTGGGAGTTAAAGCTATTGATGGTTTCTTAACTTGCGGAAGAGGACAA
AGGATAGGTATCTTTGCTGGTTCAGGAGTAGGTAAATCTACTTTACTTGGTATGATAGCAAGAAATACCTTGGCTGATAT
AAACGTAATTGCACTTATTGGAGAGCGTGGAAGAGAAGTTAAGGAATTCATAGACAATGATTTAGAAGAAGAAGGCTTAA
AAAAATCTGTAGTAATAGTTGTTACTTCTGATCAGCCACCTTTAGTTAGAATGAAAGGAGCCTTGCTTGCGACATCTATA
GCTGAATATTTTAGGGATTGTGGCAAAAATGTCGTTTTAATGATGGACTCACTAACTAGATTTTCCATGGCTCAAAGAGA
AGTTGGACTTGCTATAGGAGAACCCCCTGTTACAAAAGGATATACTCCATCGGTTTTTGCAGTTCTACCCAAATTGCTTG
AAAGAGCAGGAAATTCTAGTAAAGGTTCAATCACAGGTCTATATACAGTTCTTGTAGATGGAGACGATATGAATGAGCCA
ATTGCAGATGCTGTTAGAGGTATACTAGATGGACATATTGTTTTATCTAGAAACTTAGCAAATAAAAATCATTATCCAGC
TATAGATATTCTAGCTAGCGTAAGTAGAGTAATGCCTAATATAGTTGATAAAGAACATATTGACATCGTAGGTCGAATAA
AGGATTTGATGGCAACTTATAGAGACTCCGAAGATTTGATAAATATAGGAGCTTATATTAAAGGGACAAACAAAAAAGTA
GATATGGCAATAGAAAAAATAGAAATCATCAATGAATTTTTAAGACAAGGAATTCATGATAGATTGACCTTTGATGAAAT
TGTAGAACTATTAAGAGGTATCTTAGATTAG

Protein sequence :
MIVNLKKYHDRLNEISLYQYKGKVSRVIGLTIESRGPAVRLGETCHIYPIKSKEPVLAEVVGFKEDTVLLMPLGEMEGIG
PGSMVVATGNTLEVDVGEQLLGRILDGMGNPIDDFEPPSLNYSYPVNNQPPNPLSRTKISEPLPLGVKAIDGFLTCGRGQ
RIGIFAGSGVGKSTLLGMIARNTLADINVIALIGERGREVKEFIDNDLEEEGLKKSVVIVVTSDQPPLVRMKGALLATSI
AEYFRDCGKNVVLMMDSLTRFSMAQREVGLAIGEPPVTKGYTPSVFAVLPKLLERAGNSSKGSITGLYTVLVDGDDMNEP
IADAVRGILDGHIVLSRNLANKNHYPAIDILASVSRVMPNIVDKEHIDIVGRIKDLMATYRDSEDLINIGAYIKGTNKKV
DMAIEKIEIINEFLRQGIHDRLTFDEIVELLRGILD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lscN AAO18044.1 LscN Virulence TTSS locus Protein 5e-114 55
escN NP_290268.1 hypothetical protein Virulence LEE Protein 2e-97 52
ECs4568 NP_312595.1 EscN Virulence LEE Protein 2e-97 52
escN AAC38383.1 EscN Virulence LEE Protein 3e-97 52
escN AAC31513.1 L0034 Virulence LEE Protein 1e-97 52
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 1e-97 52
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 3e-97 52
escN YP_003236088.1 translocator EscN Virulence LEE Protein 2e-97 52
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 8e-100 51
unnamed AAL06369.1 EscN Virulence LEE Protein 8e-95 51
escN AAK26715.1 EscN Virulence LEE Protein 3e-97 51
escN AAL57542.1 EscN Virulence LEE Protein 3e-97 51
escN YP_003223475.1 translocator EscN Virulence LEE Protein 2e-97 51
escN CAC81862.1 EscN protein Virulence LEE II Protein 2e-97 51
escN CAI43874.1 EscN protein Virulence LEE Protein 1e-97 51
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 6e-100 50
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 6e-100 50
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 3e-100 50
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 2e-100 50
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-98 50
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-98 50
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 8e-100 50
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-100 50
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 2e-92 50
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 3e-90 49
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 3e-90 49
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 1e-88 48
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 3e-89 48
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 3e-89 48
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 7e-89 48
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 3e-89 48
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 8e-90 47
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 4e-78 45
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 9e-81 45
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 6e-81 45
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 7e-84 45
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 3e-84 45
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 1e-84 45
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 6e-78 44
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 4e-88 44
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 2e-80 43
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 7e-75 42
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 7e-75 42
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 4e-77 41
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 8e-73 41
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 8e-73 41
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 8e-73 41
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 8e-73 41
invC AAS66861.1 InvC Not tested SSR-2 Protein 9e-76 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
fliI YP_003936763.1 flagellum-specific ATP synthase VFG2144 Protein 4e-116 56
fliI YP_003936763.1 flagellum-specific ATP synthase VFG0390 Protein 6e-114 55
fliI YP_003936763.1 flagellum-specific ATP synthase VFG0192 Protein 8e-117 55
fliI YP_003936763.1 flagellum-specific ATP synthase VFG0048 Protein 3e-108 53
fliI YP_003936763.1 flagellum-specific ATP synthase VFG1254 Protein 5e-103 53
fliI YP_003936763.1 flagellum-specific ATP synthase VFG0730 Protein 2e-97 52
fliI YP_003936763.1 flagellum-specific ATP synthase VFG0812 Protein 8e-98 52
fliI YP_003936763.1 flagellum-specific ATP synthase VFG2331 Protein 4e-98 50
fliI YP_003936763.1 flagellum-specific ATP synthase VFG2499 Protein 1e-93 49
fliI YP_003936763.1 flagellum-specific ATP synthase VFG0515 Protein 4e-89 48
fliI YP_003936763.1 flagellum-specific ATP synthase VFG1008 Protein 1e-74 42
fliI YP_003936763.1 flagellum-specific ATP synthase VFG0555 Protein 3e-73 41