Gene Information

Name : clpB (CLOST_0173)
Accession : YP_003935208.1
Strain : Clostridium sticklandii DSM 519
Genome accession: NC_014614
Putative virulence/resistance : Virulence
Product : protein disaggregation chaperone
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 200560 - 202821 bp
Length : 2262 bp
Strand : +
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 14550559, 14640692, 91294166, 93015925, 93388583, 99428468; Product type f : factor

DNA sequence :
ATGAAAAAATGTTCAGTATGTAAGAAGAATATAGCTATGCTTTTTGCTTCGACATATGAAAATGGTAAACCAGAAATGAA
AGGGCTATGCCTTAACTGTGCTAAGAAGATGAATATCCCAGGGATAGATGATCTTATAAAGCAGACAGGTATGTCAGAGG
AAGAACTATCCGCAATAACTGACCAGATGAATGACTCTATGAGTATGTTTGATGAGGATAGCGAGATGGATTTTTTATCA
AATTTTAAGGATGCTGATAAGGAAGACGAGATTCAAATAGAAGAGAATGAAGAAGCTGAGGCTCATCAAGATGAAGTAGA
AGATAAAGAGCCGTCTAAGAAAAAGAAGAAGAAAAAGAAATACCTAGATACCTTTGGAACTAACCTTACTGACAAAGCTT
CAAAAAATCAAATAGATAAGGTTATAGGAAGAGACAAAGAAATTCAAAGAGTAATTCAAATATTAAATAGAAGAGCAAAA
AACAATCCAGTACTAGTAGGAGAGCCAGGAGTAGGAAAAACTGCTATTGCAGAAGGACTAGCTGTTAGGATAGCTGAAAA
GCAAGTGCCATCAAAGCTACTAAATGCAGAGGTATATCTGCTGGATATGACTGCTGTTGTTGCTGGGACTCAGTTTAGAG
GCCAGTTCGAAGGTAGAATGAAGTCTATCATCACTGAAGCACAAAGCTACGGCAATATCATTTTAGTAATAGATGAGCTT
CACAATATCATGGGTGCAGGAGAGGTTCATGGTGGAACTATGAACGCTGCCAATATCCTAAAGCCAGCTCTTGCAAGAGG
AGATGTCCAAATCATCGGAGCAACTACTTTATCAGAGTACAGAAAGCATATCGAAAAGGATTCTGCACTTGAAAGACGCT
TTCAGCCTGTAATGGTAGATGAACCTAGTGAAGAAGAAAGCATAGAAATATTAAAAGGAATAAAAGGCTACTACGAGGAT
TATCATCAAGTGAGTATTTCTGATGAAGTCATAGAAGCGGCTGTAAAGATGTCTAATAGATATATCACAGATAGATTTTT
GCCTGACAAAGCCATAGATGTAATAGATGAGGCAGGCTCTAGAGCCAATCTTGTAAATGAAGTACTAACTAGCATCGAGG
ATTACAAAACTCAGCTGATGCAAAGCACCTACCTAAAAGATCAAGCTTCAGAAAAAGGTGATTTTGAAGGAGCAGCTTAT
TACAAGGCTGAAGAAATTCGTCTTACTCAAAAAATTGAACTGCTTGAAAAGAGTGCAAAGACACCTCTTACTATAGAAGA
TGTAGCTCATATCATAGAAGCATGGACTAAGATTCCTCTTAAATCCATAACTGAGGAAGAGGCTATAAAGCTTCTTAATC
TAGAGCAAAGGCTTCACCAAAGAGTAATAGGCCAAGATGAAGCTATATCTAGCATTTCAAGAACTGTAAGAAGAAATCGT
TCTGGCTTTAGAAAAAGAAGAAAGCCAGCATCCTTTATATTTGTAGGCCCTACAGGAGTAGGAAAGACAGAGGTAGTAAG
AGCTTTAGCAAAAGAGATGTTTGGAAGCGAAGACGACATGATAAGAATCGATATGAGTGAGTATATGGAAAGACATACAG
TATCAAAGCTCATAGGCTCACCTCCTGGATATGTAGGCTATGATGAGGGTGGACAGCTGACAGAAAAAGTAAGAAGAAGA
CCTTACTCTGTAATTTTATTTGATGAGATAGAAAAAGCTCATGCAGATGTATTTAACATGCTACTTCAGATTTTAGAGGA
TGGAAGACTTACTGATGCACAGGGCAGAACAGTATTCTTTGAAAATACTATTATAGTTATGACATCAAATGCTGGAACCT
CATATAAAAGCAAGAGCATGGGCTTTGGAAATGCAAACACTCTAGAAGAGAGCGAGCATATCAAGGATGCCCTTAAGGAA
GTTTTCAGACCTGAATTTTTAAATCGTGTGGACGATATAGTTGTGTTTACTAGACTTTCAAAGCCTCAGCTAAGAGAAAT
AGTAGACCTTATGATAAAGGAAGTTCAAACTGAGCTAGCAGAAAAAGGAATTAGTCTTCATGTGAGTGATGAAGTAAAAG
AATTCTTACTAGAAAAAGGCTATGATGACAAATATGGAGCAAGACCTCTAAGACGAGTGATACAAAGATATATTGAAGAT
GAAATATCGGAGCTATACTTGCGTAAAGAGATTCTGGATAAAGATTCAATATCAGCAATCATGCTAAATGCACAGGTAAG
TATAGTAAAAAGCCATGAATGA

Protein sequence :
MKKCSVCKKNIAMLFASTYENGKPEMKGLCLNCAKKMNIPGIDDLIKQTGMSEEELSAITDQMNDSMSMFDEDSEMDFLS
NFKDADKEDEIQIEENEEAEAHQDEVEDKEPSKKKKKKKKYLDTFGTNLTDKASKNQIDKVIGRDKEIQRVIQILNRRAK
NNPVLVGEPGVGKTAIAEGLAVRIAEKQVPSKLLNAEVYLLDMTAVVAGTQFRGQFEGRMKSIITEAQSYGNIILVIDEL
HNIMGAGEVHGGTMNAANILKPALARGDVQIIGATTLSEYRKHIEKDSALERRFQPVMVDEPSEEESIEILKGIKGYYED
YHQVSISDEVIEAAVKMSNRYITDRFLPDKAIDVIDEAGSRANLVNEVLTSIEDYKTQLMQSTYLKDQASEKGDFEGAAY
YKAEEIRLTQKIELLEKSAKTPLTIEDVAHIIEAWTKIPLKSITEEEAIKLLNLEQRLHQRVIGQDEAISSISRTVRRNR
SGFRKRRKPASFIFVGPTGVGKTEVVRALAKEMFGSEDDMIRIDMSEYMERHTVSKLIGSPPGYVGYDEGGQLTEKVRRR
PYSVILFDEIEKAHADVFNMLLQILEDGRLTDAQGRTVFFENTIIVMTSNAGTSYKSKSMGFGNANTLEESEHIKDALKE
VFRPEFLNRVDDIVVFTRLSKPQLREIVDLMIKEVQTELAEKGISLHVSDEVKEFLLEKGYDDKYGARPLRRVIQRYIED
EISELYLRKEILDKDSISAIMLNAQVSIVKSHE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 4e-150 51

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpB YP_003935208.1 protein disaggregation chaperone VFG0080 Protein 2e-154 56
clpB YP_003935208.1 protein disaggregation chaperone VFG0079 Protein 6e-157 53