Gene Information

Name : entE (Pvag_3656)
Accession : YP_003933223.1
Strain : Pantoea vagans C9-1
Genome accession: NC_014562
Putative virulence/resistance : Virulence
Product : 2,3-dihydroxybenzoate-AMP ligase
Function : -
COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism
COG ID : COG1021
EC number : 2.7.7.58
Position : 3884246 - 3885862 bp
Length : 1617 bp
Strand : -
Note : peptide arylation enzymes

DNA sequence : 
ATGACGATTGCTTACAGCCGCTGGCCGGACGATCTGGCTGCACGTTACCGTGAAAAAGGGTACTGGCTGGATCTGCCGAT
GACCGACATCCTGGAACGTCACCGCGACAGCGAATGCGTGGCGGTGATTGATGGCGACCGGCAATTTACCTATCGCCAGA
TGGCCTCACTGAGTGACAATCTGGCAGCGGCCCTGCAGCATCGTGGCCTGAAACCCGGTGATACGGCGCTGGTGCAGCTT
GGCAACGTGGCGGAATTTTATCTGACGCTGTTTGCGCTGTTCAAAATCGGCGTCGCCCCGGTTAACGCTCTTTTCAGCCA
TCAACGTACCGAACTGGTCGCCTATGCCAGTCAGATCGCGCCGTGCCTGTTGATTGCCGATCGCAGCCATCCCCTGTTCG
CCGATGACGCCTTTATCACGCAGCTTCGCCGGGAACAGCATTCACTGCAGCAGGTGATCCTGCGTAATGACGCTCATGCG
GAAAACAGTCTCGACGCCCTGCTGGCAGAACCCGCAGGTGACTTCAGGGCAACCCCGACCGCAGGCGATGACGTCGCTTT
TTTCCAGCTGTCGGGCGGCAGTACCGGCACTCCGAAGCTGATCCCGCGTACCCACAATGATTACTACTACAGCATCCGGG
AAAGTGACGTGATCTGCGGGGTCAACGCAGATACCCGTTACCTGATTGCTCTGCCCGCTGCACATAATTTCCCGATGAGT
TCTCCGGGCGCGCTGGGCGTCTTTTACGCGGGCGGCCAGGTGATCTTAGCGGCCGATCCCAGCGCGACCCTCTGTTTCCC
GCTGATTGAAAAACATCAGGTTACTGATACCGGCCTGGTTCCACCCGCGGCCAGTCTCTGGCTGCAGGCGATTCAGGAAT
GGGGCAGCAATGCCGCGCTGGCCTCACTGCAACGTATTCAGGTCGGTGGCGCAAAGCTGGGTGAAACGCTGGCTGCGCGC
ATCCAGAACGAGATGGGCTGTACCCTTCAGCAGGTGTTTGGGATGGCGGAGGGTCTGGTGAACTACACCCGGCTGGATGA
CGATGAACAGACCATTCTCACCACGCAGGGCCGTCCGATCTCACCGGATGACGAGGTGTGGGTCGCAGACGAACAGGGGC
ATCCGCTGCCGGTCGGTGCCATTGGGCGCCTGATGACACGCGGTCCTTATACGTTCCGTGGCTACTACAACAGCCCGGAA
CATAACGCCGCCAGCTTTGATGACCAGGGCTTTTACTGCTCTGGCGATCTGGTTGAGATCACCCCCGCTGGCAACATCAT
TGTGCAGGGTCGTGAGAAAGATCAGATCAACCGGGGCGGCGAAAAGATCGCAGCTGAAGAGATTGAAAACCTGCTGCAGC
GCCATGCGGATGTGATCCACGCGGCGCTGGTCTCTATGAGCGACGAACTGATGGGTGAAAAGAGCTGTGCGTTTATTGTC
ACCCGTCAGCCGGTGAAACCGGTGGCGCTGCGTCGTCACCTGCGTGAACTGGGCGTCGCCGAATTTAAGCTGCCCGACCG
TATTACCTGCGTAGATGCCCTGCCGCTGACCGCGGTCGGCAAGGTAGACAAAAAACGTCTGCGCCAACAACTTGCCGATC
AGCGTGCGCAAGCCTGA

Protein sequence : 
MTIAYSRWPDDLAARYREKGYWLDLPMTDILERHRDSECVAVIDGDRQFTYRQMASLSDNLAAALQHRGLKPGDTALVQL
GNVAEFYLTLFALFKIGVAPVNALFSHQRTELVAYASQIAPCLLIADRSHPLFADDAFITQLRREQHSLQQVILRNDAHA
ENSLDALLAEPAGDFRATPTAGDDVAFFQLSGGSTGTPKLIPRTHNDYYYSIRESDVICGVNADTRYLIALPAAHNFPMS
SPGALGVFYAGGQVILAADPSATLCFPLIEKHQVTDTGLVPPAASLWLQAIQEWGSNAALASLQRIQVGGAKLGETLAAR
IQNEMGCTLQQVFGMAEGLVNYTRLDDDEQTILTTQGRPISPDDEVWVADEQGHPLPVGAIGRLMTRGPYTFRGYYNSPE
HNAASFDDQGFYCSGDLVEITPAGNIIVQGREKDQINRGGEKIAAEEIENLLQRHADVIHAALVSMSDELMGEKSCAFIV
TRQPVKPVALRRHLRELGVAEFKLPDRITCVDALPLTAVGKVDKKRLRQQLADQRAQA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-91 43
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-91 43
ybtE CAA21394.1 - Virulence HPI Protein 1e-91 43
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 1e-91 43
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 2e-91 43
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-91 43
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 1e-91 43
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 8e-91 43
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-90 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
entE YP_003933223.1 2,3-dihydroxybenzoate-AMP ligase VFG0932 Protein 0.0 69
entE YP_003933223.1 2,3-dihydroxybenzoate-AMP ligase VFG0168 Protein 3e-104 44