Gene Information

Name : topB (Pvag_1545)
Accession : YP_003931182.1
Strain : Pantoea vagans C9-1
Genome accession: NC_014562
Putative virulence/resistance : Unknown
Product : DNA topoisomerase III
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0550
EC number : 5.99.1.2
Position : 1625501 - 1627417 bp
Length : 1917 bp
Strand : -
Note : Topoisomerase IA

DNA sequence :
ATGCGTTTGTTTATTGCGGAAAAACCGAGCCTTGGGCGTGCTATCGCAGATGTGCTGCCGAAACCGCATCGCCGCGGTGA
TGGCTTTATTGCCTGCGGCAACGATCAGATCGTCACCTGGTGCGTGGGACACCTTCTTGAGCAGGCGCAGCCCGACAGTT
ATGACAGTCGTTACGCGCGCTGGTCGCTGAACGATCTGCCGATCATTCCGGAAAAATGGCAGCTGAAACCGCGTCCGTCG
GTTGCGAAGCAGCTGAAAGTGGTGGAGGGTCTGCTGGCGCAGGCGAGTGAAGTGGTGCATGCCGGTGACCCGGATCGGGA
AGGGCAGTTGCTGGTGGATGAGGTACTGGATTACCTGAACCTGCCCCCTGAAAAACGCAGTAAAGTGCAGCGCTGTCTGA
TCAACGATCTTAACCCTCAGGCAGTGGATCGCGCCGTAAATCGCCTGCGTGAGAATCGCGAGTTTATCCCGCTGTGCGTT
TCTGCGCTGGCCCGCGCCCGTGCGGACTGGCTCTACGGCATCAATATGACCCGCGCCTGGACGCTGCTGGGACGCAATGC
CGGCTACGATGGTGTGCTGTCAGTAGGCCGGGTACAGACACCGGTGTTGGGGCTGGTAGTGCGGCGCGATGAAGAGATCG
AGAACTTCGTGCCGAAAGACTACTTCGAAGTTAAAGCGCATATCCTCACGCCTGATGGTGCCAGATTTGTTGCCAGCTGG
ATCCCCAGCGAAGCCTGTGAGCCGTGGCAGGATGAAGAGGGACGGCTGCTCAAACGCGCACTGGCCGATCATGTGGTGGC
GCGTATCACCGGTCAGCCTGCCATCGTCACGGCCTACAGCGATAAGCGCGAAAATGACGTCGCTCCGTTGCCATTCTCCC
TGTCCAGTCTGCAGATCGAGGCCGCGAAACGTTACGGACTGAGTGCCCAGACGGTCCTGGACACCTGTCAGCGGCTCTAT
GAAACCCACAAACTGATTACCTACCCGCGTTCAGACAGCCGCTATCTGCCGGAAGAGCATTTTGCCGGTCGTCGTACGGT
CTTGAAGGCGATACAGGCGCATCAGCCCCAGCTCACGCCACCAGCAGACTTTAACGCCGATCGCAGAAATCGCTGCTGGG
ACGATAAAAAAGTCGATGCTCACCATGCCATTATTCCCACGGCCCGAAGCAGCGCGGTTAAGCTCAGTGAAAACGAACAG
CACATTTATGAGCTGGTAGCGCGCCAGTATCTGATGCAGTTCTGCCCGGATGCGGTATTCCGTAAATGTGTCATCGATCT
TGATATTGCGGGCGGAAAGTTTATGGCGAAAGCGCGCTTCCTCGCAGAGGCTGGCTGGCGTGCGCTGCTGGGCAGCAAAG
AGCGGGATGAAGAGAACGACGGCATGCCGCTGCCGGTAGTGGCGAAAGGCGATGAGTTGCTGTGTGAGCGTGGCGAGGTG
CTGGCGAAGCAGACTCAGCCGCCTCGACCGTTTACCGATGCCACCATTCTTTCTGCAATGACCGGCATCGCCCGTTTCGT
TCAGGATAAAGAATTAAAGAAAGTGCTGCGTGCGACCGATGGTTTAGGAACGGAAGCCACACGCGCCGGCATTATCGAAT
TACTGTTTCGTCGTGGCTTCCTGGTGAAGAAGGGCCGTTACATCAATTCCACGGATGCCGGACGCGCCCTGATTCACTCT
CTGCCCGATCTGGCAGCGCGCCCGGATATGACGGCGCAGTGGGAATCGACACTGACGCGTATCAGCGAAAAGGCCTGCCG
CTATGATGAGTTTATGCAGCCGCTGGTGCAGACCTTAACCGGCCTTATCCAGCAGGCGCGGCAGCAGCCTGCGGCGCATG
CATTTCGGGGATTACCGTCCACCGGACAGAAACGTCCGGTGCGCAAAACCAGGCGTAAAGTGAAGGAGACGGAATGA

Protein sequence :
MRLFIAEKPSLGRAIADVLPKPHRRGDGFIACGNDQIVTWCVGHLLEQAQPDSYDSRYARWSLNDLPIIPEKWQLKPRPS
VAKQLKVVEGLLAQASEVVHAGDPDREGQLLVDEVLDYLNLPPEKRSKVQRCLINDLNPQAVDRAVNRLRENREFIPLCV
SALARARADWLYGINMTRAWTLLGRNAGYDGVLSVGRVQTPVLGLVVRRDEEIENFVPKDYFEVKAHILTPDGARFVASW
IPSEACEPWQDEEGRLLKRALADHVVARITGQPAIVTAYSDKRENDVAPLPFSLSSLQIEAAKRYGLSAQTVLDTCQRLY
ETHKLITYPRSDSRYLPEEHFAGRRTVLKAIQAHQPQLTPPADFNADRRNRCWDDKKVDAHHAIIPTARSSAVKLSENEQ
HIYELVARQYLMQFCPDAVFRKCVIDLDIAGGKFMAKARFLAEAGWRALLGSKERDEENDGMPLPVVAKGDELLCERGEV
LAKQTQPPRPFTDATILSAMTGIARFVQDKELKKVLRATDGLGTEATRAGIIELLFRRGFLVKKGRYINSTDAGRALIHS
LPDLAARPDMTAQWESTLTRISEKACRYDEFMQPLVQTLTGLIQQARQQPAAHAFRGLPSTGQKRPVRKTRRKVKETE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
topB1 YP_005176228.1 DNA topoisomerase III Not tested ICEPmu1 Protein 9e-110 42
topB NP_458624.1 topoisomerase B Not tested SPI-7 Protein 1e-107 41
topB NP_807836.1 DNA topoisomerase III Not tested SPI-7 Protein 1e-107 41
topB AAF14809.1 topoisomerase B Not tested SPI-7 Protein 8e-108 41
topB AAN62317.1 putative DNA topoisomerase III Not tested PAGI-3(SG) Protein 4e-105 41
topB AAN62194.1 putative DNA topoisomerase III Not tested PAGI-2(C) Protein 2e-107 41
pph56 CAI36097.1 Topoisomerase IA Not tested PPHGI-1 Protein 2e-101 41