Gene Information

Name : HPSJM_02765 (HPSJM_02765)
Accession : YP_003928464.1
Strain : Helicobacter pylori SJM180
Genome accession: NC_014560
Putative virulence/resistance : Virulence
Product : cag pathogenicity island protein (cag26)
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 549621 - 553166 bp
Length : 3546 bp
Strand : +
Note : -

DNA sequence :
ATGACTAACGAAACTATTGACCAACAACCACAAACCGAAGCGGCTTTTAACCCGCAGCAATTTATCAATAACCTTCAGGT
AGCTTTTCTTAAGCTTGATAACGCTGTCGCTTCATTTGATCCTGATCAAAAACCAATCGTTGATAAGAATGATAGGGATA
ACAGGCAAGCTTTTGATGGAATCTCGCAATTAAGGGAAGAATACTCCAATAAAGCGATCAAAAATCCTACCAAAAAGAAT
CAGTATTTTTCAGACTTTATCAATAAGAGCAATGATTTAATCAACAAAGACGCTCTCATTGATGTAGAATCTTCCACAAA
GAGCTTTCAGAAATTTGGGGATCAGCGTTACCGAATTTTCACAAGTTGGGTGTCCCATCAAAACGATCCGTCTAAAATCA
ACACCCGATCGATCCGAAATTTTATGGAACATACCATACAACCCCCTATCCCTGATGACAAAGAAAAAGCAGAGTTTTTG
AAATCTGCCAAACAATCTTTTGCAGGAATCATTATAGGGAATCAAATCCGAACGGATCAAAAGTTCATGGGCGTGTTTGA
TGAATCCTTGAAAGAAAGGCAAGAAGCAGAAAAAAATGGAGGGCCTAGTGGTGGGGATTGGTTGGATATTTTTTTATCAT
TTATATTTGACAAAAAACAATCTTCTGATGTCAAAGAAGCAATCAATCAAGAACCAGTTCCCCATGTCCAACCAGATATA
GCCACTACCACCACCGACATACAAGGCTTACCACCTGAATCTAGGGATTTGCTTGATGAAAGGGGTAATTTTTCTAAATT
CACTCTTGGTGATATGAACATGTTAGATGTTGAGGGAGTCGCTGACATTGATCCCAATTACAAGTTCAATCAATTATTGA
TTCACAATAACGCTCTGTCTTCTGTGTTAATGGGGAGTCATAATGGCATAGAACCTGAAAAAGTTTCATTATTGTATGCG
GGCAATGGTGGTTTTGGAGCCAAGCACGATTGGAACGCCACCGTTGGTTATAAAGACCAACAAGGTAACAATGTGGCCAC
AATAATTAATGTGCATATGAAAAACGGCAGTGGCTTAGTCATAGCAGGTGGTGAGAAAGGGATTAACAACCCTAGTTTTT
ATCTCTACAAAGAAGACCAACTCACAGGCTCACAACGAGCATTGAGTCAAGAAGAGATCCGAAACAAAATAGATTTCATG
GAATTTCTTGCACAAAACAATGCTAAATTAGACAACTTGAGCGAGAAAGAGAAAGAAAAATTCCGAAATGAGATTAAGGA
TTTTCAAAAAGACTCTAAGGCTTATTTAGACGCCCTAGGGAATGATCGTATTGCTTTTGTTTCTAAAAAAGACCCAAAAC
ATTCAGCTTTAATTACTGAGTTTAATAAGGGGGATTTGAGCTACACTCTCAAAGATTATGGGAAAAAAGCAGATAAAGCT
TTAGATAGGGAGAAAAATGTCACTCTTCAAGGTAACCTAAAACATGATGGCGTGATGTTTGTTGATTATTCTAATTTCAA
ATACACCAACGCCTCCAAGAATCCCAATAAGGGTGTCGGCGCTACGAATGGCGTTTCCCATTTAGACGCAGGCTTTAGCA
AGGTAGCTGTCTTTAATTTGCCTGATTTAAATAATCTCGCTATCAATAGTTTCGTAAGGCGGAATTTAGAGGATAAACTA
GTCGCTAAAGGATTGCCCCCACAAGAAGCTAATAAGCTTATCAAAGATTTTTTGAGCAGCAACAAAGAATTGGTTGGAAA
GGCTTTAAACTTCAATAAAGCTGTAGCTGACGCTAAAAACACAGGCAACTATGACGAGGTGAAAAAAGCTCAGAAAGATC
TTGAAAAATCTCTAAGGAAACGAGAGCATTTAGAGAAAGAAGTAGAGAAAAAATTGGAGAGCAAAAGCGGCAACAAAAAT
AAAATGGAAGCAAAAGCTCAAGCTAACAGCCAGAAAGATGAGATTTTTGCGTTGATCAATAAAGAGGCTAATAGAGACGC
AAGAGCAATCACTTACAGTCAAAATCTTAAAGGTATCAAAAGGGAATTGTCTGATAAGCTTGAAAGCATCAACAAGGATT
TGAAAGACTTTAGTAAATCTTTTGATGAATTCAAAAATGGCAAAAATAAGGATTTCAGCAAGGCAGAAGAAACACTAAAA
GCCCTTAAAGGCTCGGTGAAAGATTTAGGTATCAATCCGGAATGGATTTCAAAAGTTGAAAACCTTAATGCAGCTTTGAA
TGACTTCAAAAATGGCAAAAATAAGGATTTCAGCAAGGTAACGCAAGCAAAAATCGACCTTGAAAATTCCATTAAAGATA
CGATTATCAATCAAAAGATAACGGATAAAGTTGATGATCTCAATCAAGCGGTATCAGTGGCTAAAGCAACGGGTGATTTC
AGTAGGGTAGAGCAAGCGTTAGCCGATCTCAAAAATTTCTCAAAGGAGCAATTGGCTCAACAAACTCAAAAAAATGAAAG
TTTCAATGTTGGGAAAAAATCTGAAATATACCAGTCCGTTAAGAATGGTGTGAACGGAACCCTAGTCGGTAATGGGTTAT
CTCAAGTAGAAGCCACAACTCTTTCTAAAAACTTTTCGGACATCAAGAAAGAGTTGAATGCAAAACTTTTTGGAAATTTT
AATAACAATAACAATAATGGACTCAAAAACGAACCCATTTATGCTAAAGTTAATAAAAAGAAAACAGAACAAGCAGCTAG
CCCTGAAGAACCCATTTATACTCAAGTTGCTAAAAAGGTAACTCAAAAAATTGACCGACTCAATCAAATAGCAAGTGGTT
TGGGTGGTGTAGGGCAAGCAGCGGGCTTCCCTTTGAAAAGGCATGATAAAGTTGAAGATCTCAGTAAGGTAGGGCGATCA
GTTAGCCCTGAACCCATTTATGCTACGATTGATGATCTCGGCGGACCTTTCCCTTTGAAAAGGCATGATAAAGTTGATGA
TCTCAGTAAGGTAGGGCTTTCAAGGGAGCAACAATTGAAACAGAAGATTGACAATCTCAGTCAAGCGGTATCAGAAGCTA
AAGCAGGTTTTTTTGGCAATCTAGAGCAAACGATAGACAAGCTCAAAGATTCTACAAAACACAATCCCATGAATCTATGG
GTTGAAAGTGCAAAAAAAGTGCCTACTAGTTTGTCAGCGAAACTAGACAATTACGCTACTAACAGCCACACACGCATTAA
TAGCAATATCAAAAATGGAGCAATCAATGAAAAAGCGACCGGCATGCTGACGCAAAAAAATCCTGAGTGGCTCAAGCTCG
TGAATGATAAGATAGTTGCGCATAATGTGGGAAGCGTTCCTTTGTCAGAGTATGATAAAATTGGCTTCAACCAGAAGAAT
ATGAAAGATTATTCTGATTCGTTCAAGTTTTCCACCAAGTTGAACAATGCTGTAAAAGACGTTAAATCTGGCTTTACGCA
ATTTTTAGCCAATGCATTTTCTACAGGATATTACTGCTTGGCGGGAGAAAATGCGGAGCATGGAATCAAAAATGTTAATA
CAAAAGGTGGTTTCCAAAAATCTTAA

Protein sequence :
MTNETIDQQPQTEAAFNPQQFINNLQVAFLKLDNAVASFDPDQKPIVDKNDRDNRQAFDGISQLREEYSNKAIKNPTKKN
QYFSDFINKSNDLINKDALIDVESSTKSFQKFGDQRYRIFTSWVSHQNDPSKINTRSIRNFMEHTIQPPIPDDKEKAEFL
KSAKQSFAGIIIGNQIRTDQKFMGVFDESLKERQEAEKNGGPSGGDWLDIFLSFIFDKKQSSDVKEAINQEPVPHVQPDI
ATTTTDIQGLPPESRDLLDERGNFSKFTLGDMNMLDVEGVADIDPNYKFNQLLIHNNALSSVLMGSHNGIEPEKVSLLYA
GNGGFGAKHDWNATVGYKDQQGNNVATIINVHMKNGSGLVIAGGEKGINNPSFYLYKEDQLTGSQRALSQEEIRNKIDFM
EFLAQNNAKLDNLSEKEKEKFRNEIKDFQKDSKAYLDALGNDRIAFVSKKDPKHSALITEFNKGDLSYTLKDYGKKADKA
LDREKNVTLQGNLKHDGVMFVDYSNFKYTNASKNPNKGVGATNGVSHLDAGFSKVAVFNLPDLNNLAINSFVRRNLEDKL
VAKGLPPQEANKLIKDFLSSNKELVGKALNFNKAVADAKNTGNYDEVKKAQKDLEKSLRKREHLEKEVEKKLESKSGNKN
KMEAKAQANSQKDEIFALINKEANRDARAITYSQNLKGIKRELSDKLESINKDLKDFSKSFDEFKNGKNKDFSKAEETLK
ALKGSVKDLGINPEWISKVENLNAALNDFKNGKNKDFSKVTQAKIDLENSIKDTIINQKITDKVDDLNQAVSVAKATGDF
SRVEQALADLKNFSKEQLAQQTQKNESFNVGKKSEIYQSVKNGVNGTLVGNGLSQVEATTLSKNFSDIKKELNAKLFGNF
NNNNNNGLKNEPIYAKVNKKKTEQAASPEEPIYTQVAKKVTQKIDRLNQIASGLGGVGQAAGFPLKRHDKVEDLSKVGRS
VSPEPIYATIDDLGGPFPLKRHDKVDDLSKVGLSREQQLKQKIDNLSQAVSEAKAGFFGNLEQTIDKLKDSTKHNPMNLW
VESAKKVPTSLSAKLDNYATNSHTRINSNIKNGAINEKATGMLTQKNPEWLKLVNDKIVAHNVGSVPLSEYDKIGFNQKN
MKDYSDSFKFSTKLNNAVKDVKSGFTQFLANAFSTGYYCLAGENAEHGIKNVNTKGGFQKS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
HP0547 BAD14045.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 94
cagA AAF17598.1 CagA Virulence cag PAI Protein 0.0 94
cagA AAR03970.1 CagA Virulence cag PAI Protein 0.0 93
cagA AAR03881.1 CagA Virulence cag PAI Protein 0.0 93
cagA AAC44706.1 CagA Virulence cag PAI Protein 0.0 92
HP0547 NP_207343.1 cag pathogenicity island protein (cag26) Virulence cag PAI Protein 0.0 92
cagA BAD51747.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 92
cagA AAR03909.1 CagA Virulence cag PAI Protein 0.0 91
cagA BAC10428.1 CagA Virulence cag PAI Protein 0.0 91
HP0547 BAD13908.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 91
cagA AAR03939.1 CagA Virulence cag PAI Protein 0.0 86
cagA NP_223213.1 cag island protein, cytotoxicity associated immunodominant antigen Virulence cag PAI Protein 0.0 85
cagA BAD51750.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 85
cagA BAD51758.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 85
cagA BAD51751.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 85
cagA BAD51760.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 85
cagA BAD51752.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 84
cagA BAD51756.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 84
cagA BAD51761.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 84
cagA BAD51766.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 84
cagA YP_003728762.1 cytotoxin-associated protein A Virulence cag PAI Protein 0.0 84
cagA AGC69806.1 cag pathogenicity island protein A Virulence cag PAI Protein 0.0 84
cagA BAC10429.1 CagA Virulence cag PAI Protein 0.0 84
HP0547 BAD13935.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 84
cagA BAC10432.1 CagA Virulence cag PAI Protein 0.0 84
HP0547 BAD13990.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 84
cagA BAD51759.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 83
cagA BAD51753.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 83
cagA BAD51764.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 81
cagA BAC10424.1 CagA Virulence cag PAI Protein 0.0 79
cagA BAC10426.1 CagA Virulence cag PAI Protein 0.0 78
cagA BAC10421.1 CagA Virulence cag PAI Protein 0.0 78
HP0547 BAD13799.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 78
cagA BAD51755.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 78
cagA BAC10435.1 CagA Virulence cag PAI Protein 0.0 78
cagA YP_005779046.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 78
cagA BAC10419.1 CagA Virulence cag PAI Protein 0.0 78
HP0547 BAD14072.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 78
cagA YP_005775747.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 78
cagA YP_005774524.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 77
cagA BAD51754.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 77
cagA BAC10420.1 CagA Virulence cag PAI Protein 0.0 77
cagA BAC10433.1 CagA Virulence cag PAI Protein 0.0 77
HP0547 BAD14018.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 77
cagA YP_005777288.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 77
cagA BAC10431.1 CagA Virulence cag PAI Protein 0.0 77
HP0547 BAD13963.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 77
cagA BAD51749.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 77
cagA BAD51762.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 77
HP0547 BAD13880.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 77
cagA AAF17597.1 CagA Virulence cag PAI Protein 0.0 77
cagA BAD51744.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 76
cagA BAC10427.1 CagA Virulence cag PAI Protein 0.0 74
HP0547 BAD13853.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 74
cagA BAC10423.1 CagA Virulence cag PAI Protein 0.0 69
cagA BAC10430.1 CagA Virulence cag PAI Protein 0.0 68
cagA BAC10422.1 CagA Virulence cag PAI Protein 0.0 67
HP0547 BAD13826.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 67

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
HPSJM_02765 YP_003928464.1 cag pathogenicity island protein (cag26) VFG0306 Protein 0.0 92