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Name : HPSJM_02650 (HPSJM_02650) Accession : YP_003928443.1 Strain : Helicobacter pylori SJM180 Genome accession: NC_014560 Putative virulence/resistance : Virulence Product : cag island protein Function : - COG functional category : U : Intracellular trafficking, secretion and vesicular transport COG ID : COG2948 EC number : - Position : 525301 - 530781 bp Length : 5481 bp Strand : + Note : COG2948 Type IV secretory pathway, VirB10 components DNA sequence : ATGAATGAAGAAAACGATAAACTTGAAACTTCTAAAAAAGCCCAACAACATTCACCCCAAGATCTATCTAATGAAGAAGC AACAGAAGCCAATCATTTTGAAGATCTTTTAAAAGAAGAAAGCTCAGACAATCATCTTGACAATTCCACAGAAACTCAAA CCCATTTTGATGAAGACAAGCTAGAAGAAACCCAAACTCAAATGGATTCTGAAGGTAATGAAACTTCAGAATCTAGCAAT GGCAGTCTAGCAGACAAGTTATTCAAAAAAGCCAGAAAATTAGTTGATAATAAAAGACCTTTCACTCAGCAAAAGAATTT AGATGAAGAAACCCAAGAATTGAACGAAGAAGACGATCAAGAAAATAATGAGTATCAAGAAGAAACTCAAACGGGCTTAA TTGATGATGAAACTTCTAAAAAAGCCCAACAACATTCACCCCAAGATTTATCCAATGAAGAAGCAACAGAAGTCAATCAT TTTGAAGATCTTTTAAAAGAAGAAAGCTCAGACAATCATCTTGACAACCCCACAGAAAGCTCAGACAATCATCTTGACAA TTCCACAGAAAGCTCAGACAATCATCTTGACAACCCCACAGAAACTAAAACCCAAGAAACTAAAACCCATTTTGATGAAG ACAAGCTAGAAGAAATAACTGACGACTCTAACGATCAAGAGATTATCAAAGGAAGCAAAAAGAAATACATTATTGGTGGC ATTGTAGTCGCTGTTCTTATCGTGATTATTTTATTTTCTAGAAGCATTTTTCACTACTTTATGCCTTTGGAAGATAAAAG CTCTCGTTTTAGCAAAGACAGGAATCTTTATGTCAATGATGAAATCCAAATAAGGCAAGAGTATAACCGATTGCTGAAAG AACGGAATGAAAAAGGCAATATGATCGATAAGAATCTTTTCTTCAATGACGATCCCAATAGAACCTTATACAACTATTTG AATATTGCAGAAATTGAGGACAAAAACCCATTGAGAGCCTTTTATGAGTGTATTGGTAATGGTGGCAACTATGAAGAATG TTTGAAGCTTATCAAAGACAAAAAACTTCAAGAGCAAATGAAAAAGACTCTAGAGGCTTATAATGATTGTATCAAAAATG CCAAAACTGAAGAAGAAAGGATCAAGTGTTTAGATTTAATCAAAGATGAAAACCTGAAAAAAAGCTTACTGAACCAACAA AAAGTTCAAGTGGCGCTAGATTGTTTGAAAAACGCTAAAACCGATGAAGAACGGAAAGAGTGCCTAAAACTCATAAATGA CCCTGAGATTAGAGAGAAATTCCGTAAGGAATTAGAGCTTCAAAAAGAGCTTCAAGAGTATAAGGATTGTATCAAAAACG CCAAAACAGAAGCTGAGAAAAACGAATGCTTGAAAGGCTTATCTAAAGAAGCTATAGAAAGATTGAAACAACAAGCGCTA GATTGTTTGAAAAACGCTAAAACCGATGAAGAACGAAACGAGTGCTTGAAAAATATTCCCCAAGACTTGCAAAAAGAACT ACTAGCTGATATGAGCGTCAAGGCTTACAAGGACTGCGTTTCAAGAGCTAGGAATGAAAAAGAGAAAAAAGAGTGTGAGA AATTGCTCACGCCTGAAGCGAAAAAAAAGTTAGAACAACAGGTTCTAGATTGTCTGAAAAACGCTAAAACCGATGAAGAA CGAAAAAAGTGTTTGAAAGATCTCCCTAAAGACTTACAAAGCGATATTTTAGCTAAAGAGAGTCTGAAAGCTTATAAAGA CTGCACATCTCAAGCCAAAACTGAAGATGAGAAAAAAGAGTGTGAGAAATTACTCACCCCTGAAGCGAAAAAACTTTTAG AAGAAGAAGCCAAAGAGAGCGTTAAGGCTTATTTGGATTGCGTATCTCAAGCCAAAACTGAAGATGAGAAAAAAGAGTGT GAGAAATTACTCACCCCTGAAGCGAAAAAAAAGTTAGAAGAAGCTAAAAAAAGCGTTAAGGCTTATTTGGATTGCGTATC TCAAGCCAAAACTGAAGATGAGAAAAAAGAGTGTGAGAAATTACTCACCCCTGAAGCGAAAAAACTTTTAGAGCAACAAG CACTAGATTGTTTGAAAAACGCTAAAACCGATGAAGAACGGAAAGAGTGCTTGAAAGATCTCCCTAAAGACTTACAGAAA AAGGTTTTAGCCAAAGAGAGTGTTAGGGTTTATTTGGATTGCGTATCAAAAGCCAAAAACGAAGCTGAAAGAAAAGAATG CGAGAAATTGCTCACGCCTGAAGCGAGGAAACTATTAGAAGAAGCTAAAGAGAGCGTTAAGGCTTATTTAGACTGCGTTT CAAGAGCTAGGAATGAAAAAGAGAAAAAAGAGTGTGAGAAATTACTCACTCCTGAAGCGAGAAAACTATTAGAAGAATCT AAAAAAAGCGTTAAGGCTTATTTGGATTGCGTATCTCAAGCCAAAAACGAAGCTGAAAGAAAAGAATGCGAGAAATTGCT CACCCCTGAAGCGAGAAAACTTTTAGAAGAAGCTAAAGAGAGCGTTAAGGCTTACAAGGACTGCGTATCAAGAGCTAGGA ATGAAAAAGAGAAAAAAGAGTGTGAGAAATTACTCACGCCTGAAGCGAGGAAACTATTAGAAGAATCTAAAAAAAGCGTT AAGGCTTATTTGGATTGCGTATCTCAAGCCAAAAACGAAGCTGAAAGAAAAGAATGCGAGAAATTACTCACGCCTGAAGC GAGAAAACTTTTAGAAGAAGCTAAAAAGAGCGTTAAGGCTTATTTAGACTGCGTATCAAGAGCTAGGAATGAAAAAGAGA AAAAAGAGTGTGAGAAATTACTCACCCCTGAAGCGAGGAAACTATTAGAGAATCAAGCACTAGATTGTTTGAAAAACGCT AAAACCGAAGCTGAGAAAAAAAGGTGTGTCAAAGATCTCCCTAAAGACTTACAGAAAAAGGTTTTAGCCAAAGAGAGTGT TAGGGTTTATTTGGATTGCGTGTCAAAAGCCAAAAACGAAGCTGAAAGAAAAGAATGCGAGAAATTACTCACGCCTGAAG CGAGAAAACTTTTAGAAGAAGCTAAAGAGAGCGTTAAGGCTTACAAAGACTGCGTATCAAGAGCTAGGAACGAAAAAGAG AAGCAAGAATGCGAGAAATTACTCACCCCTGAAGCGAGGAAACTATTAGAGCAAGAAGTTAAAAAGAGCGTTAAGGCTTA TTTAGACTGCGTATCAAGAGCTAGGAATGAAAAAGAGAAAAAAGAGTGTGAGAAATTGCTCACCCCTAAAGCGAGGAAAC TATTAGAGAATCAAGCGCTAGATTGTTTGAAAAACGCTAAAACCGAAGCTGAGAAAAAAAGGTGTGTCAAAGATCTCCCT AAAGACTTACAGAAAAAGGTTTTAGCTAAAAAAAGCGTTAAGGCTTATTTAGACTGCGTTTCAAGAGCTAGGAATGAAAA AGAGAAACAAGAATGCGAGAAATTACTCACGCCTGAAGCGAGAAAGCTATTAGAAGAAGCTAAAAAAAGCGTTAAGGCTT ATTTAGACTGCGTTTCAAGAGCTAGGAATGAAAAAGAGAAACAAGAATGCGAGAAATTACTCACGCCTGAAGCGAGAAAG CTATTAGAAGAAGCTAAAGAGAGCCTTAAAGCTTATAAAGACTGTCTCTCTCAAGCTAGAAATGAAACTGAAAGGAGAGC CTGCGAGAAATTACTCACCCCTGAAGCGAGAAAACTATTAGAGCAAGAAGTTAAAAAGAGCGTTAAGGCTTATTTAGACT GCGTTTCAAGAGCTAGGAATGAAAAAGAGAAACAAGAATGCGAGAAATTACTCACGCCTGAAGCGAGGAAATTTTTAGAG AAACAGCGCCAACAAAAAGATAAAGCGATAAAGGATTGCTTGAAAAACGCCGATCCTAACGACAGAGCGGCTATCATGAA GTGTTTGGATGGTTTGAGCGATGAAGAGAAGCTCAAATACCTGCAAGAAGCTAGAGAAAAGGCTGTCTTGGATTGTTTGA AAACGGCTAGGACCGATGAAGAAAAAAGAAAATGCCAAAACCTTTATAGCGATTTGATCCAAGAAATCCAAAATAAAAGG GCACAGAACAAACAAAATCAATTGAGTAAAACAGAAAGGTTGCATCAAGCAAGCGAGTGCTTGGATAACTTAGATGACCC TACTGATCAAGAAGCCATAGAGCAATGTTTAGAGGGATTGAGCGATAGCGAAAGGGCGCTAATTCTAGGAATCAAACGAC AAGCTGATGAAGTGGATCGGATTTATAGCGATCTAAGAAGCCGCAAAACCTTTGATAACATGGCGGCTAAAGGTTATCCA TTGTTACCAATGGATTTCAAAAATGGTGGCGATATTGCCACTATTAACGCCACTAATGTTGATGCGGACAAAATAGCTAG CGATAATCCTATTTATGCTTCCATAGAGCCTGATATTACTAAGCAATACGAAACAGAGAAAACCATTAAGGATAAGAGTT TAGAAGCTAAATTAGCTAAGGCTTTAGGTGGCGATAAAAAAGATGACGATAAAGAAAAAAGTAAAAAACCCACAGCAGAA ACTAAAGCAGAAAGCAATAAGATAGACAAAGATGTCGCAGAAACTGCCAAAAATATCAGCGAAATCGCTCTTAAGAACAA AAAAGAAAAGAGTGGGGATTTTGTAGATGAAAATGGTAATCCCATTGACGATAAAAAGAAAGAAGAAAAACAAGATGAAA CAAGCCCTGTCAAACAGGCCTTTATAGGCAAGAGTGATCCCACATTTGTTTTAGCGCAATACACTCCCATTGAAATCACT CTGACTTCTAAAGTAGATGCCACTCTCACGGGTATAGTGAGTGGGGTTGTAGCCAAAGATGTATGGAACATGAACGGCAC TATGATCTTATTAGACAAAGGCACTAAGGTGTATGGGAATTATCAAAGCGTGAAAGGTGGCACACCTATTATGACTCGTT TAATGATAGTCTTTACTAAAGCCATTACGCCTGATGGGGTGATTATACCTCTAGCAAACGCTCAAGCAGCAGGCATGTTG GGTGAAGCAGGGGTAGATGGCTATGTGAATAATCACTTCATGAAGCGCATAGGCTTTGCTGTGATAGCAAGCGTGGTTAA TAGCTTCTTGCAAACCGCGCCTATCATAGCCCTAGATAAACTCATAGGCCTTGGCAAAGGCAGAAGTGAAAGGACACCTG AATTTAATTACGCTTTGGGTCAAGCTATCAATGGCAGTATGCAAAGTTCAGCTCAGATGTCTAATCAAATTCTAGGGCAA CTGATGAATATCCCCCCAAGTTTTTACAAAAATGAGGGCGATAGCATTAAGATTCTCACAATGGACGATATTGATTTTAG CGGCGTGTATGATGTTAAAATTACCAACAAATCTGTGGTAGATGAAATTATCAAACAAAGCACCAAAACTTTGTCTAGAG AACATGAAGAAATCACCACAAGCCCCAAAGGTGGCAATTGA Protein sequence : MNEENDKLETSKKAQQHSPQDLSNEEATEANHFEDLLKEESSDNHLDNSTETQTHFDEDKLEETQTQMDSEGNETSESSN GSLADKLFKKARKLVDNKRPFTQQKNLDEETQELNEEDDQENNEYQEETQTGLIDDETSKKAQQHSPQDLSNEEATEVNH FEDLLKEESSDNHLDNPTESSDNHLDNSTESSDNHLDNPTETKTQETKTHFDEDKLEEITDDSNDQEIIKGSKKKYIIGG IVVAVLIVIILFSRSIFHYFMPLEDKSSRFSKDRNLYVNDEIQIRQEYNRLLKERNEKGNMIDKNLFFNDDPNRTLYNYL NIAEIEDKNPLRAFYECIGNGGNYEECLKLIKDKKLQEQMKKTLEAYNDCIKNAKTEEERIKCLDLIKDENLKKSLLNQQ KVQVALDCLKNAKTDEERKECLKLINDPEIREKFRKELELQKELQEYKDCIKNAKTEAEKNECLKGLSKEAIERLKQQAL DCLKNAKTDEERNECLKNIPQDLQKELLADMSVKAYKDCVSRARNEKEKKECEKLLTPEAKKKLEQQVLDCLKNAKTDEE RKKCLKDLPKDLQSDILAKESLKAYKDCTSQAKTEDEKKECEKLLTPEAKKLLEEEAKESVKAYLDCVSQAKTEDEKKEC EKLLTPEAKKKLEEAKKSVKAYLDCVSQAKTEDEKKECEKLLTPEAKKLLEQQALDCLKNAKTDEERKECLKDLPKDLQK KVLAKESVRVYLDCVSKAKNEAERKECEKLLTPEARKLLEEAKESVKAYLDCVSRARNEKEKKECEKLLTPEARKLLEES KKSVKAYLDCVSQAKNEAERKECEKLLTPEARKLLEEAKESVKAYKDCVSRARNEKEKKECEKLLTPEARKLLEESKKSV KAYLDCVSQAKNEAERKECEKLLTPEARKLLEEAKKSVKAYLDCVSRARNEKEKKECEKLLTPEARKLLENQALDCLKNA KTEAEKKRCVKDLPKDLQKKVLAKESVRVYLDCVSKAKNEAERKECEKLLTPEARKLLEEAKESVKAYKDCVSRARNEKE KQECEKLLTPEARKLLEQEVKKSVKAYLDCVSRARNEKEKKECEKLLTPKARKLLENQALDCLKNAKTEAEKKRCVKDLP KDLQKKVLAKKSVKAYLDCVSRARNEKEKQECEKLLTPEARKLLEEAKKSVKAYLDCVSRARNEKEKQECEKLLTPEARK LLEEAKESLKAYKDCLSQARNETERRACEKLLTPEARKLLEQEVKKSVKAYLDCVSRARNEKEKQECEKLLTPEARKFLE KQRQQKDKAIKDCLKNADPNDRAAIMKCLDGLSDEEKLKYLQEAREKAVLDCLKTARTDEEKRKCQNLYSDLIQEIQNKR AQNKQNQLSKTERLHQASECLDNLDDPTDQEAIEQCLEGLSDSERALILGIKRQADEVDRIYSDLRSRKTFDNMAAKGYP LLPMDFKNGGDIATINATNVDADKIASDNPIYASIEPDITKQYETEKTIKDKSLEAKLAKALGGDKKDDDKEKSKKPTAE TKAESNKIDKDVAETAKNISEIALKNKKEKSGDFVDENGNPIDDKKKEEKQDETSPVKQAFIGKSDPTFVLAQYTPIEIT LTSKVDATLTGIVSGVVAKDVWNMNGTMILLDKGTKVYGNYQSVKGGTPIMTRLMIVFTKAITPDGVIIPLANAQAAGML GEAGVDGYVNNHFMKRIGFAVIASVVNSFLQTAPIIALDKLIGLGKGRSERTPEFNYALGQAINGSMQSSAQMSNQILGQ LMNIPPSFYKNEGDSIKILTMDDIDFSGVYDVKITNKSVVDEIIKQSTKTLSREHEEITTSPKGGN |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| orf13/14 | NP_223194.1 | cag island protein | Virulence | cag PAI | Protein | 0.0 | 96 |
| HP0527 | BAD13915.1 | cag pathogenicity island protein | Virulence | cag PAI | Protein | 0.0 | 86 |
| cagY | YP_005775730.1 | cag pathogenicity island protein Y VirB10-like protein | Virulence | cag PAI | Protein | 0.0 | 85 |
| HP0527 | BAD13860.1 | cag pathogenicity island protein | Virulence | cag PAI | Protein | 0.0 | 85 |
| HP0527 | BAD13806.1 | cag pathogenicity island protein | Virulence | cag PAI | Protein | 0.0 | 80 |
| HP0527 | BAD13888.1 | cag pathogenicity island protein | Virulence | cag PAI | Protein | 0.0 | 79 |
| cagY | AGC69786.1 | cag pathogenicity island protein Y | Virulence | cag PAI | Protein | 0.0 | 79 |
| HP0527 | BAD13970.1 | cag pathogenicity island protein | Virulence | cag PAI | Protein | 0.0 | 78 |
| HP0527 | BAD14052.1 | cag pathogenicity island protein | Virulence | cag PAI | Protein | 0.0 | 78 |
| HP0527 | NP_207323.1 | cag pathogenicity island protein (cag7) | Virulence | cag PAI | Protein | 0.0 | 78 |
| cagY | AGC69787.1 | cag pathogenicity island protein Y | Virulence | cag PAI | Protein | 0.0 | 78 |
| HP0527 | BAD13998.1 | cag pathogenicity island protein | Virulence | cag PAI | Protein | 0.0 | 77 |
| HP0527 | BAD13833.1 | cag pathogenicity island protein | Virulence | cag PAI | Protein | 0.0 | 77 |
| cagY | YP_005777271.1 | cag pathogenicity island protein Y VirB10-like protein | Virulence | cag PAI | Protein | 0.0 | 77 |
| HP0527 | BAD14026.1 | cag pathogenicity island protein | Virulence | cag PAI | Protein | 0.0 | 77 |
| cagY | YP_003728737.1 | cag pathogenicity island protein Y | Virulence | cag PAI | Protein | 0.0 | 77 |
| HP0527 | BAD13943.1 | cag pathogenicity island protein | Virulence | cag PAI | Protein | 0.0 | 77 |
| cagY | YP_005774542.1 | cag pathogenicity island protein | Virulence | cag PAI | Protein | 0.0 | 77 |
| HP0527 | BAD13779.1 | cag pathogenicity island protein | Virulence | cag PAI | Protein | 0.0 | 76 |
| cagY | YP_005779063.1 | cag island protein | Virulence | cag PAI | Protein | 0.0 | 76 |
| cag-Y | AAF80198.1 | Cag-Y | Virulence | cag PAI | Protein | 0.0 | 76 |
| cagY | AGC69789.1 | cag pathogenicity island protein Y | Virulence | cag PAI | Protein | 0.0 | 76 |
| cagY | AGC69785.1 | cag pathogenicity island protein Y | Virulence | cag PAI | Protein | 0.0 | 74 |
| cagY | AGC69788.1 | cag pathogenicity island protein Y | Virulence | cag PAI | Protein | 0.0 | 74 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| HPSJM_02650 | YP_003928443.1 | cag island protein | VFG0287 | Protein | 0.0 | 78 |
