Gene Information

Name : guaA (HPPC_05060)
Accession : YP_003927275.1
Strain : Helicobacter pylori PeCan4
Genome accession: NC_014555
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 1028608 - 1030134 bp
Length : 1527 bp
Strand : -
Note : COG0518 GMP synthase - Glutamine amidotransferase domain

DNA sequence :
ATGATTTTAGTATTAGATTTTGGGAGCCAATACACACAGCTGATTGCTAGAAGATTGAGAGAGAGCGGGATTTATGCAGA
AATAGTCCCTTTTTTTGAAAGCGTAGAAAACATTCAAAAAAAAGCCCCTAAAGGTTTGATTTTGAGCGGGGGGCCAGCGA
GCGTGTATGCTAAAGACGCTTACAAGCCTAGCGAGAAAATCTTTGATTTGAATTTACCGATTTTAGGGATTTGCTACGGC
ATGCAGTATCTAGTGGATTTTTTTGGGGGGGCAGTCGTTTGTGCGAATGAGCAGGAATTTGGTAAGGCTATCTTAGAAAT
CACTCAAGATTCTGTGATTTTTGAAGGCGTGAAAATTAAAAGCCTTGTGTGGATGAGCCATATGGATAAAGTTATAGAAT
TGCCTAAAGGCTTCACTACCCTTGCAAAAAGCCCCAATTCCCCCCATTGCACGATTGAAAGCGCTAAGATTTTTGGCTTG
CAATTCCACCCAGAAGTCATTCAAAGCGAAGAAGGGGGTAAGATTTTAGAAAATTTTGCCCTTTTGGTTTGTGGCTGTGA
AAAAACTTGGGGGATGCAGCATTTCGCTCAAAGAGAAATCGCACGATTGAAAGAAAAAATTGCTAACGCTAAGGTTTTGT
GCGCGGTGAGTGGGGGCGTGGATTCTACGGTGGTCGCTACGCTATTATACAGAGCCATTAAGGATAATTTGATCGCTGTT
TTTGTGGATCATGGTTTGTTGCGTAAAAATGAAAAAGAAAAAGTGCAAGCGATGTTTAAAGACTTACAAATCCCTTTAAA
CACGATAGACGCTAAAGAGATCTTTTTGTCTAAATTAAAGGGCGTGAGCGAGCCTGAATTGAAGCGAAAAATCATCGGCG
AAACCTTTATTGAAGTGTTTGAAAAAGAAGCCAAGAAGCACCATTTGAAAGGCAAAATTGAGTTTTTAGCCCAAGGCACT
TTATACCCTGATGTGATTGAATCCGTGAGCGTTAAAGGGCCTTCAAAAGTGATCAAAACCCATCATAATGTGGGAGGACT
GCCTGAATGGATGGACTTCAAACTCATAGAGCCTTTAAGGGAATTGTTTAAAGATGAGGTCCGTTTGTTGGGTAAGGAAT
TGGGCATTAGCCAGGATTTTTTGATGCGCCACCCCTTTCCAGGGCCTGGGCTTGCGATAAGGATTTTAGGCGAAGTCAGC
GAGAGTAAGATCAGATGCTTGCAAGAAGCGGATTTTATTTTTATAGAAGAGCTTAAAAAGGCCAATTTGTATGACAAGGT
TTGGCAGGCTTTTTGCGTGCTGTTGAATGTCAATTCTGTGGGGGTTATGGGAGATAATCGCACTTATGAAAACGCTATTT
GTTTAAGGGCAGTAAATGCGAGCGATGGCATGACAGCGAGCTTTTCGTTTTTAGAGCATTCTTTTTTAGAAAAGGTTTCT
AATCGTATCACTAATGAAGTGAGCGGTATCAATAGGGTGGTGTATGATATTACCTCTAAACCACCAGGAACGATTGAATG
GGAATGA

Protein sequence :
MILVLDFGSQYTQLIARRLRESGIYAEIVPFFESVENIQKKAPKGLILSGGPASVYAKDAYKPSEKIFDLNLPILGICYG
MQYLVDFFGGAVVCANEQEFGKAILEITQDSVIFEGVKIKSLVWMSHMDKVIELPKGFTTLAKSPNSPHCTIESAKIFGL
QFHPEVIQSEEGGKILENFALLVCGCEKTWGMQHFAQREIARLKEKIANAKVLCAVSGGVDSTVVATLLYRAIKDNLIAV
FVDHGLLRKNEKEKVQAMFKDLQIPLNTIDAKEIFLSKLKGVSEPELKRKIIGETFIEVFEKEAKKHHLKGKIEFLAQGT
LYPDVIESVSVKGPSKVIKTHHNVGGLPEWMDFKLIEPLRELFKDEVRLLGKELGISQDFLMRHPFPGPGLAIRILGEVS
ESKIRCLQEADFIFIEELKKANLYDKVWQAFCVLLNVNSVGVMGDNRTYENAICLRAVNASDGMTASFSFLEHSFLEKVS
NRITNEVSGINRVVYDITSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 5e-133 53
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 6e-133 53
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 6e-133 53
guaA NP_938969.1 GMP synthase Not tested Not named Protein 1e-114 48