Gene Information

Name : HPPC_01340 (HPPC_01340)
Accession : YP_003926565.1
Strain : Helicobacter pylori PeCan4
Genome accession: NC_014555
Putative virulence/resistance : Virulence
Product : ATP-dependent protease binding subunit / heatshock protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 259880 - 262450 bp
Length : 2571 bp
Strand : +
Note : COG0542 ATPases with chaperone activity, ATP-binding subunit

DNA sequence :
ATGAATTTATTTGAAAAAATGACTGACCAATTGCATGAAACTTTAGACAGCGCGCTCGCTCTAGCCTTACACCATAAAAA
CGCTGAAGTAACGCCCTTGCACATGCTTTTTGCCATGCTCAATAACTCCCAAGGCATTCTCATTCAAGCCTTACAAAAAA
TGCCTGTGGATATTGAAGCTTTAAAACTTAGCGTTCAAAGCGAGTTGAATAAGTTCGCTAAAGTCTCACAAATCAGCAAG
CAAAACATCCAATTAAACCAAGCTTTAATCCAAAGTTTAGAAAACGCTCAAGGCTTGATGGCTAAAACGGGCGATTCTTT
CATCGCTACCGATGTGTATCTTTTGGCGAATATGAATCTTTTTGAAAGCGTTCTAAAGCCTTATTTAGACACTAAGGAAT
TGCAAAAAACTTTAGAATCTTTAAGAAAAGGCAGGACTATCCAGGATAAAAATGATGATTCCAATTTGGAAAGTTTAGAA
AAATTTGGCATTGATTTGACGCAAAAAGCCTTAGAAAATAAGCTCGATCCGGTGATTGGGAGGGATGAAGAAATCATTCG
CATAATGCAAATTTTGATAAGAAAAACAAAAAATAACCCTATTTTACTCGGTGAGCCTGGAGTGGGGAAAACGGCAGTTG
TGGAGGGTTTGGCCCAACGCATTGTGAATAAAGAAGTGCCTAAAACGCTTTTAAACAAACGAGTCGTCGCTTTAGATTTA
AGCTTATTGGTGGCTGGAGCCAAATATAGAGGCGAGTTTGAAGAGCGTTTGAAAAAGGTGATTGAAGAAGTTAAAAAAAG
TGCGAATGTGATTTTATTCATTGATGAAATCCACACGATCGTAGGGGCTGGGGCTAGTGAGGGGGGCATGGATGCGGCTA
ATATCTTAAAACCCGCGCTCGCTAGGGGGGAATTGCACACGATTGGAGCGACCACTTTGAAAGAATACCGCAAGTATTTT
GAAAAAGACATGGCATTGCAAAGGCGTTTCCAACCCATTTTACTCAATGAGCCTAGCATCAATGAAGCTTTACAGATTTT
AAGGGGGTTAAAAGAAACTTTAGAAACGCACCATAATATCACTATCAATGACTCCGCACTCATAGCGAGCGCCAAACTCT
CTAGCCGTTATATCACCGATAGGTTTTTACCCGATAAAGCGATTGATTTGATTGATGAAGGGGCGGCCCAATTAAAAATG
CAAATGGAATCAGAGCCGGCAAAGCTCTCTAGCGTTAAGCGCTCCGTTCAAAGATTGGAAATGGAAAAACAAGCCCTTGA
AATGGAAAAAAAAGAGAGCAATGCCAAACGCATGCAAGAAATCCTTAAAGAATTGAGCGATTTGAAAGAAGAAAAAATCC
AATTAGAAGCGCAATTTGAGAATGAAAAAGAAGTGTTTAGAGAAATTTCACGCTTGAAAATGGAAACGGAAAGCTTGAAA
AAAGAGGCTGAGAGGTTTAAGCGCAATGGGGATTACCAGCAAGCGGGTGAAATTGAATACTCTAAAATCCCTGAAAATAA
AAAGAAAGAAGAAGAATTGCAGCATAAATGGGAAGCGATGCAACAAAACGGGGCGTTGTTGCAAAACGCTTTAACCGAAA
ACAACATCGCTGAGATCGTGAGCCAATGGACGCATATCCCGGTCCAAAAAATGCTCCAGAGCGAAAAAAATAGGGTTTTA
AACATTGAAAGCGAATTGCAAAAAAGAGTGGTGGGGCAAGAAAAAGCGATCAAAGCGATCGCTAAAGCGATTAAAAGGAA
TAAGGCCGGGCTTAGCGATAGCAATAAGCCCATAGGGAGCTTTCTCTTTTTAGGGCCAACGGGTGTGGGTAAAACCGAGA
GCGCTAAAGCTTTGGCGCAATTCTTGTTTGATAGCGATAAAAATCTTATAAGAATTGACATGAGCGAATACCTAGAAAAA
CATGCCATAAGCCGTCTTATTGGGGCCGCTCCTGGGTATGTGGGCTATGAAGAAGGCGGGCAATTGACCGAAGCGGTGCG
CAGAAAACCCTATAGCGTGGTGCTGTTAGATGAAGTGGAAAAAGCCCATCCGGATGTGTTTAACCTCTTGTTGCAGGTTT
TAGATGAAGGGCATTTAACCGATAGTAAGGGCGTGAGGGTGGATTTCAAAAACACGATTTTGATTTTAACCAGCAATGTG
GCTAGCGGCGTGCTTTTGGAAGAAAATTTGAGTGAAGCCGATAAACAAAAAGCGATCAAAGAGAGCTTGAGGCAATTCTT
CAAGCCAGAATTTTTAAACCGCTTAGATGAAATCATCTCCTTTAACGCCCTAGATAGCCATGCTATCGCTAATATCGTGG
GGATTCTCTTTGAAAACATTCAAAAAAAAGCGCTTGAAAGAGGCATTAATATAACCCTAGACGAAGAGGCAAAAGAATTG
ATCGCCAAAGCGGGGTTTGACAGATTCTATGGCGCTAGACCCTTGAAGCGCGCGCTCTATGAAATGGTAGAAGACAAGCT
CGCTGAACTCATTTTAGAGGATAAAATTAAAGAGAATGACAGCGTGGCGTTTGTGGTAGAAAATAACGAAATTGTGCCTA
AGATTAAGTGA

Protein sequence :
MNLFEKMTDQLHETLDSALALALHHKNAEVTPLHMLFAMLNNSQGILIQALQKMPVDIEALKLSVQSELNKFAKVSQISK
QNIQLNQALIQSLENAQGLMAKTGDSFIATDVYLLANMNLFESVLKPYLDTKELQKTLESLRKGRTIQDKNDDSNLESLE
KFGIDLTQKALENKLDPVIGRDEEIIRIMQILIRKTKNNPILLGEPGVGKTAVVEGLAQRIVNKEVPKTLLNKRVVALDL
SLLVAGAKYRGEFEERLKKVIEEVKKSANVILFIDEIHTIVGAGASEGGMDAANILKPALARGELHTIGATTLKEYRKYF
EKDMALQRRFQPILLNEPSINEALQILRGLKETLETHHNITINDSALIASAKLSSRYITDRFLPDKAIDLIDEGAAQLKM
QMESEPAKLSSVKRSVQRLEMEKQALEMEKKESNAKRMQEILKELSDLKEEKIQLEAQFENEKEVFREISRLKMETESLK
KEAERFKRNGDYQQAGEIEYSKIPENKKKEEELQHKWEAMQQNGALLQNALTENNIAEIVSQWTHIPVQKMLQSEKNRVL
NIESELQKRVVGQEKAIKAIAKAIKRNKAGLSDSNKPIGSFLFLGPTGVGKTESAKALAQFLFDSDKNLIRIDMSEYLEK
HAISRLIGAAPGYVGYEEGGQLTEAVRRKPYSVVLLDEVEKAHPDVFNLLLQVLDEGHLTDSKGVRVDFKNTILILTSNV
ASGVLLEENLSEADKQKAIKESLRQFFKPEFLNRLDEIISFNALDSHAIANIVGILFENIQKKALERGINITLDEEAKEL
IAKAGFDRFYGARPLKRALYEMVEDKLAELILEDKIKENDSVAFVVENNEIVPKIK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 2e-140 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
HPPC_01340 YP_003926565.1 ATP-dependent protease binding subunit / heatshock protein VFG0079 Protein 4e-158 43
HPPC_01340 YP_003926565.1 ATP-dependent protease binding subunit / heatshock protein VFG2076 Protein 3e-111 42