Gene Information

Name : mccB (BAMF_2533)
Accession : YP_003921129.1
Strain : Bacillus amyloliquefaciens DSM 7
Genome accession: NC_014551
Putative virulence/resistance : Resistance
Product : cystathionine lyase/ homocysteine gamma-lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : -
Position : 2579908 - 2581050 bp
Length : 1143 bp
Strand : -
Note : 'intermediary metabolism; Metabolism of amino acids and related molecules'

DNA sequence :
ATGAAGAAAAAAACGCTGATGGTACACGGAGGAATTACGGGAGATGAAAAAACAGGAGCGGTTTCCGTACCGATTTATCA
AGTAAGCACGTACCGGCAGCCGAAAGCGGGCGAGCACACGGGTTATGAATATTCAAGAACGGCCAATCCGACGCGGACGG
CGCTTGAAAGCTTAATTGCGGAGCTTGAAGGCGGCGCGGCGGGATATGCGTTCGGCTCAGGCATGGCTGCGATTACTGCC
GTCATGATGCTGTTTGACAGCGGCGATCATGTTATTTTGACGGATGATGTATACGGCGGCACTTACCGGGTGATGACAGG
TGTGCTGAACCGCTTCGGTATTGAAGCGGACTTTGTTGATACGAGCAGTGAAGAAAAAGTCAAAAAGGCCATTCGCCCGA
ATACGAAAGCCATTTATATCGAAACACCGACAAACCCGCTATTGAAAGTGACTGACCTCAAACTGATGTCTGACATCGCA
AAAGAAGCGGGCGTATTGCTTATCGTCGATAATACGTTTTACACGCCGTATTTCCAGCAGCCGCTCAGCTTCGGCGCGGA
CATCGTGCTTCACAGCGCGACAAAATATCTCGGCGGCCACAGCGATGTCGTCGGCGGCTTAGTCGTGACGGCTGATAAAG
AGCTCGGTGAAAAGCTTCATTACGTGCAAAACTCAACGGGCGGCGTTTTAGGACCGCAGGATTCATGGCTTTTAATGAGA
GGCATTAAAACACTGGGACTCAGAATGGATGCCATCAATCACAGCGCCGGGAAAATCGCCGAGCTGCTTGAAGCGCATGA
TGCCGTTCAGACGCTCTACTATCCGGGATCAGCGAAACATCCGGGCCATGAGCTGACAAAAGCGCAAAGCTCCGGTTTCG
GCGGAATGATTTCCTTTGATATCGGCAGCAGTGAACGCGTCGACGCATTTTTAGAAAAATTGAACCTGTTTACAATCGCT
GAAAGCTTAGGAGCGGTTGAAAGCTTAATCTCCGTGCCGTCCAGAATGACGCACGCTTCGATCCCGCGCGACCGACGGCT
TGCGCTTGGCATTACCGACGGGCTCGTACGGATCTCAGTCGGTATTGAGGATACTGAGGATTTAACGGCGGATGTGAAAC
AGGCGCTTGATTCCCTTTTATAA

Protein sequence :
MKKKTLMVHGGITGDEKTGAVSVPIYQVSTYRQPKAGEHTGYEYSRTANPTRTALESLIAELEGGAAGYAFGSGMAAITA
VMMLFDSGDHVILTDDVYGGTYRVMTGVLNRFGIEADFVDTSSEEKVKKAIRPNTKAIYIETPTNPLLKVTDLKLMSDIA
KEAGVLLIVDNTFYTPYFQQPLSFGADIVLHSATKYLGGHSDVVGGLVVTADKELGEKLHYVQNSTGGVLGPQDSWLLMR
GIKTLGLRMDAINHSAGKIAELLEAHDAVQTLYYPGSAKHPGHELTKAQSSGFGGMISFDIGSSERVDAFLEKLNLFTIA
ESLGAVESLISVPSRMTHASIPRDRRLALGITDGLVRISVGIEDTEDLTADVKQALDSLL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 9e-112 62
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-110 61
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 1e-74 44

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
mccB YP_003921129.1 cystathionine lyase/ homocysteine gamma-lyase BAC0207 Protein 9e-66 43