Gene Information

Name : hpcH (AARI_06170)
Accession : YP_003915816.1
Strain : Arthrobacter arilaitensis Re117
Genome accession: NC_014550
Putative virulence/resistance : Unknown
Product : 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG3836
EC number : 4.1.2.-
Position : 686117 - 686926 bp
Length : 810 bp
Strand : +
Note : identified by similarity to protein SP:Q47098 (Escherichia coli). Involved in the homoprotocatechuic acid pathway. Catalyses the conversion of 2,4- dihydroxyhept-2-ene-1,7-dioic acid into succinic semialdehyde and pyruvic acid

DNA sequence :
ATGTCATTTCGAGTAGAACCAGATTCATCGCTGAAAGACGCGCTCAAGGACGCGGACCACTCGTTGGCCGGCGTCTGGGT
GTGCTCCGCTTCGCCGCTGATTGCTGAAATCTGCGCGGGCGCGGGATTCGACTGGCTGTTCATCGACGCCGAGCATTCGC
CCAACGACCTGCAAAATGTCCTGGCCCAGCTGCAAGCGGTACGCAGCTACCCAGTAGTTCCTGTGGTCCGCCCGGCGGTC
AACGACCCGGTGCTCATCAAGCAGTACCTGGATCTGGGCGTGCAATCGCTGATCATCCCGATGGTCAATGACGCCCAGCA
AGCCGCCGCCGCGGTAGCCGCCTGCCAGTACCCGCCTAAGGGCGTGCGCGGCGTCGGGTCGGCACTGGCTCGCTCAGCTC
GTTGGAACCGCATTCCCGAGTACCTGACCCGTGCTGATGAAACCATTACCATCATGGTGCAGATCGAAGCGGATGAAGCA
GTACGCAACGTTGAGGAAATCGTTGCCACGCCGGGCGTGGATGGAATCTTCATCGGGCCTTCGGACCTGGCTGCTTCCAT
GGGAGTCATTGGCCAGCAGAGCCACCCAGATGTGGTCGCTGCCGTGCTCAAGTCCATCAACGCCGCCAAGGCCGCTGGCA
AGTACGCCGGGGTTAACGCCTTCGACCAGAAGAGCGCCCGCGAATACATGGACGCCGGCGCGGACTACGTCGGTGTAGGC
GCCGATGTGGCGCTGCTAGCCCGTGCCACCGAAGCACTGGCTGCAAGCTTCAGCTCCGAAGCCCAAAGCAAGGCCCCGCA
GAGCTACTAG

Protein sequence :
MSFRVEPDSSLKDALKDADHSLAGVWVCSASPLIAEICAGAGFDWLFIDAEHSPNDLQNVLAQLQAVRSYPVVPVVRPAV
NDPVLIKQYLDLGVQSLIIPMVNDAQQAAAAVAACQYPPKGVRGVGSALARSARWNRIPEYLTRADETITIMVQIEADEA
VRNVEEIVATPGVDGIFIGPSDLAASMGVIGQQSHPDVVAAVLKSINAAKAAGKYAGVNAFDQKSAREYMDAGADYVGVG
ADVALLARATEALAASFSSEAQSKAPQSY

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hpaI AAO17185.1 HpaI Not tested tcd island Protein 6e-48 52