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Name : clpB (AARI_25210) Accession : YP_003917709.1 Strain : Arthrobacter arilaitensis Re117 Genome accession: NC_014550 Putative virulence/resistance : Virulence Product : chaperone protein ClpB Function : - COG functional category : O : Posttranslational modification, protein turnover, chaperones COG ID : COG0542 EC number : - Position : 2829812 - 2832400 bp Length : 2589 bp Strand : - Note : part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with dnaK, dnaJ and grpE. Acts before dnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase DNA sequence : GTGGACACCAAACTCACCACCAAGAGCCAAGAGGCCCTCTCGGCTTCCGGTATGAACGCTTCAACCGCAGGCAATCCGCA GATTGAACCTGCGCACCTGCTTAAGGCATTGCTTGACCAGCGGGAATCAGTAGCCGTGGCCCTCCTGAAGACTGCCGGAA TGGATGTCGACGCGCTTTCAGTCAAGGCTAGTGCCGTGATTAACGCGCTGCCTTCGACTTCCGGATCCTCGGTTGCCCAG GCCCAGTTCTCCCGCCAGCTGCTGCAGGTCGTGAACAACGCCCAGGAGACCGCCACCGAAATGGGGGACACCTATGTCTC CACCGAACACCTGCTGATCGCTTTGGCATCGGATCAGACCAAGGCCGGAGAAGCACTGCGCGAATTCGGCGCCACTCGTG AACTGCTGGTTGGCACCTTGCCGACCATCCGCGGGGACCGCAAGGTCAACAGTCCTGATCCGGAAGCGACCTTCCAGTCC CTGGAGAAGTTCGGCACCGACATGACCGCCTTGGCTCGCTCGGGCAAGCTGGATCCGGTCATCGGCCGTGACCGCGAAAT CCGCCGTGTGGTCCAGGTGCTTTCCCGCCGTACCAAGAACAACCCGGTACTGATCGGTGAGCCCGGCGTGGGCAAGACCG CTGTGGTTGAGGGCCTGGCCCAGCGCATGATCGCTGGCGACGTGCCAGAATCCCTGCGCGGCAAAACCCTGATTTCCCTT GATCTGGGTGCCATGGTCGCCGGCGCGAAATACCGCGGTGAATTCGAAGAGCGCCTGAAGTCGGTATTGGAAGAGATCAA GGCCTCCGATGGCCAGATCGTCACCTTCATCGATGAGATCCACACCGTCGTCGGTGCCGGTGCCTCCGAAGGTGCCATGG ACGCCGGCAACATGCTCAAGCCGATGCTGGCCCGCGGCGAGCTGCGCCTGATCGGTGCCACCACCTTGGATGAGTACCGC GAGAACATCGAGAAGGACCCGGCCCTGGAACGCCGCTTCGCCCAGGTGTATGTCGGCGAGCCGAGCGTGGATGACACCAT TGCCATCCTGCGCGGACTGAAGGAACGCTACGAAGCGCACCACAAGGTCTCGATCGCCGACTCGGCCCTGGTGGCTGCCT CCACGCTGTCCAACCGGTACATCTCCGGACGCCAGCTGCCGGACAAGGCCATCGACCTGGTCGATGAGGCCGCCAGCCGG CTGCGCATGGAGATCGACTCTGCTCCCGAGGAAATCGATGAGCTGCGCCGCGAGGTGGACCGGCTGACCATGGAAGAGCT GGCGCTGTCCGATGAGACGGATCCAGCTTCGGTGGAACGCTTGGAAGCTTTGCGCAAGGACATGGCCGACAAGAAGGAAA AGCTTGATGCGCTCAATTCCCAGTGGGAAGCGGAGAAGGCTGGACTGAACCGCGTTGGGGACTTGAAGGTCAAGCTCGAT GAGCTGCGCAGCCAGGCTGAAAAGGCCCAGCGCGAAGGGGATCTGGAGAAGGCCTCACGCCTGCTCTACGGCGAGATCCC AACGCTGCAGCAGGAACTGGACGCGGCCGCCGCTGCCGAAGCCGACAAGGCTGATGTGCACACCATGGTGGCTGAGGAAG TCACCGCGGACGACATTGCTGAAGTCATCTCGGCCTGGACGGGCATCCCGGCCGGGCGCATGCTGCAGGGCGAAAGCCAG AAGCTGCTGGAGATGGAAGAGGTCATTGGGCAGCGCCTGATGGGCCAGAAGCAGGCAGTCGCCGCGGTTTCCGACGCGGT GCGACGGACTCGCGCAGGCATTGCCGACCCGAACCGCCCAACCGGCTCCTTCCTGTTCCTTGGTCCAACGGGTGTCGGCA AGACCGAGCTGGCCAAGTCCCTGGCGGACTTCCTGTTCGATGACCCGCGTGCCATGGTGCGTATCGACATGTCCGAGTAC TCCGAGAAGCACGCGGTCTCGCGTCTGGTCGGTGCTCCTCCGGGCTATGTCGGCTACGAGGAAGGTGGACAGCTCACCGA AGCGGTACGCCGTCGCCCGTACTCGGTGATACTGCTCGACGAGGTGGAGAAAGCCCATCCAGAGGTCTTCGACATCCTGC TGCAGGTACTCGATGATGGGCGGTTGACCGATGGGCAAGGGCGCACGGTGGACTTCAGGAATACCATCCTGATTCTCACC TCCAACCTCGGTTCCCAGTTCCTGGTGGATCAGTCCTTGGAAGAGGAAGCCAAGAAGTCTGCGGTGATGAACGTGGTCAA CGCGTCATTCAAGCCAGAGTTCTTGAACCGCCTCGATGAGGTGATCCTCTTTGATCCATTGAGCATCGAAGAGCTCGGGA ACATCGTCAAGCTGCAGATCGACCTGCTGGCCCAGCGCCTGGCTGATCGCCGACTGAGCTTGATAGTGGATCCGGCCGCG AGCGAGTGGCTGGCACTGACCGGATACGACCCGGCCTACGGTGCCCGCCCATTGCGCCGTTTGGTGCAGCGCGAGATCGG TGACCGCTTGGCTAAGGAGATCCTTGCCGGAACGGTCCAAGATGGGGATGCCGTAGTGGTCAGCCTGGATGAGGCTGGTG ACAAGCTGCAGGTTGCCAAGCAGGGCTAG Protein sequence : MDTKLTTKSQEALSASGMNASTAGNPQIEPAHLLKALLDQRESVAVALLKTAGMDVDALSVKASAVINALPSTSGSSVAQ AQFSRQLLQVVNNAQETATEMGDTYVSTEHLLIALASDQTKAGEALREFGATRELLVGTLPTIRGDRKVNSPDPEATFQS LEKFGTDMTALARSGKLDPVIGRDREIRRVVQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQRMIAGDVPESLRGKTLISL DLGAMVAGAKYRGEFEERLKSVLEEIKASDGQIVTFIDEIHTVVGAGASEGAMDAGNMLKPMLARGELRLIGATTLDEYR ENIEKDPALERRFAQVYVGEPSVDDTIAILRGLKERYEAHHKVSIADSALVAASTLSNRYISGRQLPDKAIDLVDEAASR LRMEIDSAPEEIDELRREVDRLTMEELALSDETDPASVERLEALRKDMADKKEKLDALNSQWEAEKAGLNRVGDLKVKLD ELRSQAEKAQREGDLEKASRLLYGEIPTLQQELDAAAAAEADKADVHTMVAEEVTADDIAEVISAWTGIPAGRMLQGESQ KLLEMEEVIGQRLMGQKQAVAAVSDAVRRTRAGIADPNRPTGSFLFLGPTGVGKTELAKSLADFLFDDPRAMVRIDMSEY SEKHAVSRLVGAPPGYVGYEEGGQLTEAVRRRPYSVILLDEVEKAHPEVFDILLQVLDDGRLTDGQGRTVDFRNTILILT SNLGSQFLVDQSLEEEAKKSAVMNVVNASFKPEFLNRLDEVILFDPLSIEELGNIVKLQIDLLAQRLADRRLSLIVDPAA SEWLALTGYDPAYGARPLRRLVQREIGDRLAKEILAGTVQDGDAVVVSLDEAGDKLQVAKQG |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| clpC | YP_005163377.1 | ATP-dependent Clp protease ATP-binding subunit | Not tested | Not named | Protein | 4e-163 | 43 |
| STY0294 | NP_454876.1 | ClpB-like protein | Not tested | SPI-6 | Protein | 2e-107 | 43 |
| aec27 | YP_851418.1 | ATPase | Not tested | PAI II APEC-O1 | Protein | 5e-109 | 42 |
| aec27 | AAQ96721.1 | Aec27 | Not tested | AGI-1 | Protein | 4e-109 | 42 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| clpB | YP_003917709.1 | chaperone protein ClpB | VFG2084 | Protein | 6e-118 | 45 |
| clpB | YP_003917709.1 | chaperone protein ClpB | VFG2076 | Protein | 2e-118 | 43 |
