Gene Information

Name : thiC (AARI_23980)
Accession : YP_003917588.1
Strain : Arthrobacter arilaitensis Re117
Genome accession: NC_014550
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 2698928 - 2700670 bp
Length : 1743 bp
Strand : +
Note : required for the synthesis of the hydromethylpyrimidine (HMP) moiety of thiamine (4-amino-2- methyl-5-hydroxymethylpyrimidine)

DNA sequence :
GTGGAACAATTTGAACAGCACCCTGCCCACACCCTTGCCTACCGCGTGTCTGAGGGAATTTCCGTTCCCGTCACCCAGAT
CCAATTGGCTGACTCCCCCAATGGCGAGCTAAATGAACCGTTGCAGGTGTATCGCACCAGCGGACCGGGAAGCGAACCCA
CCCAAGGATTGCAGCCTTTCCGCGAACCGTGGATCCTGGAACGCGGGGATGTGGAAACCTATGAGGGTCGAGAACGCAAT
CTGCACGATGACGGACGCTCTGCGGTTCGCAGAGGCACCGCCAGCGCAGAGTGGGCCGGACGCTCGGCGCCTCCGCGAAG
GGCCGTCAGCGCAGCCCGTGTGACCCAGATGCACTATGCCCGGGCCGGGATCATCACCCCGGAAATGCGCTATGTTGCCA
TACGCGAAGAATGCGATGTCGAACTGGTGCGCAGCGAGCTTGCGGCCGGCCGGGCCATCATCCCGGCGAACATAAACCAC
CCGGAATCCGAGCCGATGATCATCGGCAAGGCCTTCTTGGTGAAGATCAATGCGAATATCGGCAATTCGGCGGTGACCAG
CTCCATCGCCGAGGAAGTCTCCAAGCTGCAGTGGGCCGCCAAGTGGGGTGCGGACACGGTCATGGACCTGTCCACCGGAG
ATGACATCCACACCACCCGCGAGTGGATCATCCGCAATTCGCCGGTGCCCATCGGCACCGTGCCGATCTACCAGGCTCTG
GAGAAGGTCAATGGCGAAGCTAATGAACTGACGTGGGAGATCTTCCGGGACACCGTCATTGAGCAGTGCGAGCAGGGCGT
GGACTACATGACCATCCACGCCGGAGTGCTGCTGCGCTACATCCCGCTGACCGCCAACCGCGTCACCGGCATGGTCTCGC
GCGGCGGGTCCATCATGGCAGGCTGGTGCTTGGCGCACCATCAGGAGAATTTCCTCTACACCCACTTCGATGAGCTGTGC
GAGATCTTCGCGCAGTACGATGTGGCGTTCTCGCTGGGCGACGGGCTGCGCCCTGGTTCCATTGCGGATGCCAATGACGC
CGCCCAGTTCGCCGAGCTGGACACCTTGGCAGAGCTGACCAAGCGCGCCTGGAAGTACGACGTTCAGGTGATGGTGGAAG
GACCGGGGCATATCCCGTTCCACCTGGTGCGCGAGAATGTGGAGCGCCAGCAGGAACTGTGCGATGGGGCTCCGTTCTAC
ACGCTGGGCCCGCTGGTCACCGATATCGCTCCGGGCTACGATCACATCACCAGCGCCATCGGCGCCACCGAGATCGCCCG
CTACGGCACCGCGATGCTCTGCTACGTCACTCCCAAGGAGCATCTGGGACTGCCTAACCGGGATGATGTGAAAACCGGCG
TCATCACCTACAAGATCGCCGCGCACGCCGCAGATCTGGCCAAGGGCCACCCTGGGGCCACGGCTCGCGATGATGCGTTG
AGCAAGGCGCGCTTCGAGTTCCGCTGGCATGACCAGTTCGCGCTGTCCCTGGACCCGGTCACAGCCCAGGAATTCCATGA
CGAGACGCTGCCGGCCGAACCAGCCAAGACCGCGCATTTCTGCTCCATGTGCGGGCCGAAGTTCTGTTCCATGCGCATTT
CCCAGGATATCCGTGACGAGTACGGATCCGCCGAGGCCCAAGCCGCGCTGGCCGGGATGGCGCAGAAGAGCAGGCAGTTC
TTGGAAAGCGGCGGCACGGTCTACCTCGGGGACCAGATCCCGTTGGGAAGCCCGGCCCCGTAA

Protein sequence :
MEQFEQHPAHTLAYRVSEGISVPVTQIQLADSPNGELNEPLQVYRTSGPGSEPTQGLQPFREPWILERGDVETYEGRERN
LHDDGRSAVRRGTASAEWAGRSAPPRRAVSAARVTQMHYARAGIITPEMRYVAIREECDVELVRSELAAGRAIIPANINH
PESEPMIIGKAFLVKINANIGNSAVTSSIAEEVSKLQWAAKWGADTVMDLSTGDDIHTTREWIIRNSPVPIGTVPIYQAL
EKVNGEANELTWEIFRDTVIEQCEQGVDYMTIHAGVLLRYIPLTANRVTGMVSRGGSIMAGWCLAHHQENFLYTHFDELC
EIFAQYDVAFSLGDGLRPGSIADANDAAQFAELDTLAELTKRAWKYDVQVMVEGPGHIPFHLVRENVERQQELCDGAPFY
TLGPLVTDIAPGYDHITSAIGATEIARYGTAMLCYVTPKEHLGLPNRDDVKTGVITYKIAAHAADLAKGHPGATARDDAL
SKARFEFRWHDQFALSLDPVTAQEFHDETLPAEPAKTAHFCSMCGPKFCSMRISQDIRDEYGSAEAQAALAGMAQKSRQF
LESGGTVYLGDQIPLGSPAP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 7e-173 66
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 7e-173 66
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 2e-163 62