Gene Information

Name : thyA (AARI_23850)
Accession : YP_003917575.1
Strain : Arthrobacter arilaitensis Re117
Genome accession: NC_014550
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 2688039 - 2688842 bp
Length : 804 bp
Strand : +
Note : catalyzes the reductive methylation of dUMP to dTMP with concomitant conversion of 5,10- methylenetetrahydrofolate to dihydrofolate

DNA sequence :
GTGAACATCGCGACCCCATACGAGACCCTGCTGCGCGACGTGCTGGAAAACGGCACTGCCAAAGAAGACCGCACCGGGAC
TGGAACCCTGTCGGTCTTTGGACGCCAGATCCGTTTCGATCTGCAGGATTCTTTCCCGCTGATCACTACCAAGCGCGTGC
ATTTCAAGTCCGTGGCAGCCGAACTGCTGTGGTTCCTGCGCGGTGAATCAAATGTGAAGTGGCTGCAGGACCAGGGCGTT
CGCATCTGGAACGAATGGGCCGATGAAGATGGCGAACTCGGCCCGGTTTACGGTGTCCAGTGGCGCAGCTGGCCCACCCC
AGAAGGTGGCTACATCGACCAGATCTCCCAGCTGGTGGACTCGCTGCGCAACAATCCAGACTCCCGCCGCCACATCGTCT
CGGCATGGAATGTCGCAGAGATCCAGAATATGGCGCTGCCTCCATGCCACGTGTTCTTCCAGTTCTACGTAGCCGACGGA
AAACTCTCCTGCCAGCTCTACCAGCGCAGTGCAGACATGTTCCTGGGCGTGCCTTTCAACATCGCTTCATACGCCCTGCT
CACTGCCATGCTGGCTCACCAGCTCGATTTGGAGCCAGGCGAGTTCATTTGGACCGGCGGCGACGTGCACATCTATACCA
ACCACGTGGAACAGGTCAAGGAACAGCTCTCACGCGATCCTTACCCGTACCCGACCCTGAGCTTCAATTCCAAGCCGGAC
TCGATCTTCGACTACACGCTGGAAGACTTCTCCATCAACGACTACCAGCACCACCCGACCATTAAGGGAACCGTAGCAGT
ATGA

Protein sequence :
MNIATPYETLLRDVLENGTAKEDRTGTGTLSVFGRQIRFDLQDSFPLITTKRVHFKSVAAELLWFLRGESNVKWLQDQGV
RIWNEWADEDGELGPVYGVQWRSWPTPEGGYIDQISQLVDSLRNNPDSRRHIVSAWNVAEIQNMALPPCHVFFQFYVADG
KLSCQLYQRSADMFLGVPFNIASYALLTAMLAHQLDLEPGEFIWTGGDVHIYTNHVEQVKEQLSRDPYPYPTLSFNSKPD
SIFDYTLEDFSINDYQHHPTIKGTVAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 4e-93 71
thyA YP_189147.1 thymidylate synthase Not tested ¥ÕSP¥â Protein 4e-51 42