Gene Information

Name : guaA (AARI_22540)
Accession : YP_003917447.1
Strain : Arthrobacter arilaitensis Re117
Genome accession: NC_014550
Putative virulence/resistance : Unknown
Product : GMP synthase (glutamine-hydrolyzing)
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 2542091 - 2543677 bp
Length : 1587 bp
Strand : -
Note : catalyzes the ATP-dependent formation of GMP from xanthosine 5-phosphate and glutamine

DNA sequence :
GTGACTACAGCTCCCCTAAATCCAGAACATAAGCCGGTTCTGGTCGTCGACTACGGGGCCCAATACGCGCAGCTTATCGC
TCGCCGCGTACGTGAGGCCCGTGTGTACTCGGAGATCGTTCCGCACACCCTGTCCACCGAAGCCATTTTGGCCAAGAACC
CTGCAGCGATCATCCTTTCCGGTGGTCCCTCCAGCGTTTACGCCGATGGCGCCCCATCCGTTGGGGCCGACCTGTTTGAA
GCCGGCGTGCCGGTCTTGGGCATCTGCTACGGCTTCCAAGCCATGGCCAATGCCTTGGGCGGAACCGTGTCGGAAACCGG
CCTGCGCGAGTACGGCCGCACCGCAACCACCTTTGATGGCGAAGCACGCTCCATCCTGGCAGGCGCCGCACAGGCTCCTA
CCGTTTGGATGAGCCACGGCGATGCCGTCTCCAAGGCTCCAGAAGGCTTTGAAGTACTGGCAACCACCGCTGGCGCTCCA
GTTGCCGCTTTCGCCAATGAGGCCAAGCGCCTGTACGGCGTGCAGTGGCACCCAGAGGTCAAGCACTGCGAGTACGGCCA
GGATGTCCTGGAGAACTTCCTGTACAACGGTGCAGGCCTGAAGGGCGACTGGACCGCTGACAACATCGCTGACGAGCAGA
TCGAGCGCATCCGCGCCCAGGTCGGCACCGGCAAGGCCATCTGCGGCCTGTCCGGCGGCGTGGATTCCGCTGTTGCAGCT
GCCCTGGTGCAGCGCGCCATCGGTGACCAGCTCACCTGCGTGTTCGTCAACCACGGCCTGCTGCGCGAAGGCGAAGCCGA
GCAGGTTGAAAAGGACTTCGTAGCTTCCACCGGCGCCAAGCTGTACATTGCCGACGAGCGCGAACGCTTCCTGACCGCTC
TGGACGGTGTCACCGATCCGGAGACCAAGCGCAAGATCATCGGCCGCGAATTCATCCGCGCCTTCGAAGCAGCAGAAGCA
GCAATCATCGCTGAAGCCGCTTCCGAGGGCGAACCGGTGAAGTTCCTGGTACAGGGCACCTTGTACCCGGACATCGTCGA
GTCCGGCGGCGGCGAAGGCACCTCGAACATCAAGAGCCACCACAACGTGGGCGGCTTGCCAGAGGACCTGCAGTTCGAAC
TGGTTGAACCACTGCGTACCCTGTTCAAGGATGAAGTACGTGCCGTGGGCCGCGAACTGGGCTTGCCTGAAGAAATCGTT
GGCCGCCAGCCATTCCCCGGCCCAGGCCTGGGTATCCGCATCATCGGCGCCGTCAACGAAGAACGCCTGTCCATCCTGCG
CAAGGCTGACGCGATCGCTCGCGCCGAGCTGACCGCTGCAGGGCTGGATGACGAAGTTTGGCAGATGCCAGTAGTGCTGC
TCGCTGACGTGCGCTCGGTAGGCGTACAGGGCGATCACCGCACCTACGGCCACCCGATCGTGCTGCGTCCGGTTTCCTCT
GAGGATGCCATGACCGCTGACTGGTCGCACCTGCCATACGATCTGCTCTCGAAGATCTCCAACCGCATCACCAATGAGGT
AGATGGGGTGAACCGCGTGGTGCTGGACGTAACCTCCAAGCCACCTGGAACCATCGAGTGGGAGTAA

Protein sequence :
MTTAPLNPEHKPVLVVDYGAQYAQLIARRVREARVYSEIVPHTLSTEAILAKNPAAIILSGGPSSVYADGAPSVGADLFE
AGVPVLGICYGFQAMANALGGTVSETGLREYGRTATTFDGEARSILAGAAQAPTVWMSHGDAVSKAPEGFEVLATTAGAP
VAAFANEAKRLYGVQWHPEVKHCEYGQDVLENFLYNGAGLKGDWTADNIADEQIERIRAQVGTGKAICGLSGGVDSAVAA
ALVQRAIGDQLTCVFVNHGLLREGEAEQVEKDFVASTGAKLYIADERERFLTALDGVTDPETKRKIIGREFIRAFEAAEA
AIIAEAASEGEPVKFLVQGTLYPDIVESGGGEGTSNIKSHHNVGGLPEDLQFELVEPLRTLFKDEVRAVGRELGLPEEIV
GRQPFPGPGLGIRIIGAVNEERLSILRKADAIARAELTAAGLDDEVWQMPVVLLADVRSVGVQGDHRTYGHPIVLRPVSS
EDAMTADWSHLPYDLLSKISNRITNEVDGVNRVVLDVTSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA NP_938969.1 GMP synthase Not tested Not named Protein 3e-169 74
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 1e-127 50
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-127 50
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 9e-128 50