Gene Information

Name : nrdE (AARI_17830)
Accession : YP_003916971.1
Strain : Arthrobacter arilaitensis Re117
Genome accession: NC_014550
Putative virulence/resistance : Unknown
Product : ribonucleoside-diphosphate reductase subunit alpha
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0209
EC number : 1.17.4.1
Position : 2024685 - 2026823 bp
Length : 2139 bp
Strand : -
Note : catalyzes the reductive synthesis of deoxyribonucleotides from their corresponding ribonucleotides. It provides the precursors necessary for DNA synthesis. It is an oligomeric enzyme composed of a large subunit (700 to 1000 residues) and a small subunit (

DNA sequence :
ATGAAGAGCTCAAAGGAGCTTCCAGCCCAGTTCCAGGGCTTGAGCTACAACGATCTGAACGCCATGCTGAACCTTTACGG
TCCAGATGGAAAGATTCAGTTTGAGGTGGACCGCTATGCTGCCCGCCAATACTTCTTGGATCACGTGAACAACAACACCG
TGTTCTTCCATGATCTCGATGAGAAGCTTGAATACCTGGTGAAGCACGAGTACTACGAGCGTGAAACCCTCGACCAGTAC
TCGATGAACTTCATCCGTGATCTGTTCAAGCACGCCTTCGGCAAGAAGTTCCGTTTTGAAACCTTCTTGGGCGCTTTCAA
GTTCTACACCTCGTACACCTTGAAGACCTTCGATGGTAAGCGCTACCTGGAACGCTACGAAGACCGCGTGTGCATGGTTG
CACTGCACCTGGCACGTGGCGATGAAAAGCTGGCTCTGCACCTGGTCGATGAGATCATCGAAGGCCGTTTCCAGCCTGCA
ACTCCAACGTTCTTGAACGCCGGCAAGGCTCAGCGCGGCGAGCTCGTCTCCTGCTTCCTGCTTCGCATTGAAGACAACAT
GGAGTCGATTGCCCGCGCCGTAAACTCCTCGCTGCAGCTTTCCAAGCGCGGCGGTGGCGTTGCGCTGTCGTTGACCAACC
TGCGCGAGCACGGTGCTCCGATCAAGCAGATCGAGAACCAGTCCTCCGGCGTCATCCCAGTGATGAAGCTTCTTGAAGAT
TCCTTCTCCTACGCAAACCAGCTCGGTGCACGTCAGGGTGCCGGTGCCGTTTACCTGAACGCACACCACCCAGACATTTA
CCGCTTCTTGGATACCAAGCGTGAAAACGCTGACGAGAAGATCCGTATCAAGACCCTGTCCCTGGGTGTTGTCATTCCGG
ATGTCACCTTCGAACTTGCTCGCAAGAACGAAGACATGTACCTGTTCAGCCCGTACGACGTTGAACGCGTCTACGGCGTA
CCGTTCAGCGAAATCTCCGTCACCGAGAAGTACTATGACATGGTCGATGACGCGCGGATCAAGAAGACCAAGATCAGCGC
ACGCGAATTCTTCCAGACCTTGGCAGAGATCCAGTTCGAGTCCGGTTACCCGTACATCATGTTCGAAGACACCGTGAACA
AGGCCAACCCAATTGCTGGCCGCATCACCATGTCGAACCTGTGCTCGGAAATCCTCCAGGTGTCCTCGGCCTCCGAGTTC
TCCGATGACTTGAGCTACAAGACCGTCGGCAAGGACATCTCCTGCAACCTCGGTTCGATGAATATCGCCAAGGCCATGGA
CGGCAAGGATCTGGCTACTTCAGTCGATATCGCCATCCGCGCGTTGAGCGCAGTTTCGGACATGTCCTACATCGCTTCGG
TACCTTCGATTGCTGATGGCAACCGTAAGTCGCACGCTATCGGCCTGGGCCAGATGAACCTGCACGGCTTCCTCGCTCGT
GAGCACATCTACTACGGTTCCGAAGAAGGCATCGACTTCACCAACATCTACTTCTACACGATTCTGTTCCATGCGCTGAC
CGCATCGAACAAGATCGCCATGGAGCGTGGTGAGACCTTCGATAACTTCGAGAACTCGAAGTACGCGTCGGGTGAGTTCT
TCGACAAGTACACCGATCAGGAATGGGTTCCAGCAACCGAACGTGTTCGCGAACTGTTCGACGGCATGCATATTCCTACC
CAGGAAGATTGGAAGACGCTGAAGGCTTCGGTTATGGAGCACGGCATCTACAACCAGAACCTGCAGGCAGTACCTCCTAC
CGGTTCGATCTCGTACATCAACAATTCGACTTCCTCGATCCACCCGGTCGCAGCGAAGATCGAGATCCGCAAGGAAGGTA
AGATCGGCCGCGTTTACTACCCGGCTCCTTACATGAACAACGAGAACATCGACTTCTACGAAGACGCTTACGAAATCGGC
TACGAGAAGATCATTGACACCTACGCTGCGGCAACCCAGCACGTGGACCAGGGCCTGTCGTTGACCTTGTTCTTCAAGGA
CACCGTCACCACTCGTGACATCAACAAGGCTCAGATCTACGCATGGCGCAAGGGCATCAAGAGCCTGTACTACATCCGCC
TTCGCCAGCTCGCGCTGGAAGGCACCGAGGTTGAAGGCTGCGTTTCCTGCGCACTGTAA

Protein sequence :
MKSSKELPAQFQGLSYNDLNAMLNLYGPDGKIQFEVDRYAARQYFLDHVNNNTVFFHDLDEKLEYLVKHEYYERETLDQY
SMNFIRDLFKHAFGKKFRFETFLGAFKFYTSYTLKTFDGKRYLERYEDRVCMVALHLARGDEKLALHLVDEIIEGRFQPA
TPTFLNAGKAQRGELVSCFLLRIEDNMESIARAVNSSLQLSKRGGGVALSLTNLREHGAPIKQIENQSSGVIPVMKLLED
SFSYANQLGARQGAGAVYLNAHHPDIYRFLDTKRENADEKIRIKTLSLGVVIPDVTFELARKNEDMYLFSPYDVERVYGV
PFSEISVTEKYYDMVDDARIKKTKISAREFFQTLAEIQFESGYPYIMFEDTVNKANPIAGRITMSNLCSEILQVSSASEF
SDDLSYKTVGKDISCNLGSMNIAKAMDGKDLATSVDIAIRALSAVSDMSYIASVPSIADGNRKSHAIGLGQMNLHGFLAR
EHIYYGSEEGIDFTNIYFYTILFHALTASNKIAMERGETFDNFENSKYASGEFFDKYTDQEWVPATERVRELFDGMHIPT
QEDWKTLKASVMEHGIYNQNLQAVPPTGSISYINNSTSSIHPVAAKIEIRKEGKIGRVYYPAPYMNNENIDFYEDAYEIG
YEKIIDTYAAATQHVDQGLSLTLFFKDTVTTRDINKAQIYAWRKGIKSLYYIRLRQLALEGTEVEGCVSCAL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1481 YP_001800875.1 ribonucleotide-diphosphate reductase subunit alpha Not tested Not named Protein 0.0 76