Gene Information

Name : AARI_01370 (AARI_01370)
Accession : YP_003915347.1
Strain : Arthrobacter arilaitensis Re117
Genome accession: NC_014550
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.3
Position : 142094 - 143617 bp
Length : 1524 bp
Strand : +
Note : catalyses the following reaction: an aldehyde + NAD(+) + H(2)O <=> an acid + NADH

DNA sequence :
ATGGCGGTTTACGCAAACCCGAACACCGATGGCGCGCTGGTTAATTTCAAGGAGCGCTACGAGAACTACATTGGCGGCCA
ATGGGTCGCCCCGACCAAGGGCATGTATTTCGAGAACGTCACCCCGGTGACCGGCAAGGTCTTCTGCGAGGTGGCCCGTT
CCACCGCCGAAGATATCGAGACTGCCCTGGATGCAGCCCATGCGGCCGCTCCTGCTTGGGGCAAGACCAGCCCTGCCGAG
CGGGCTGTCATCCTGAACAAGATCGCGGACCGCATCGAGGAAAACCTCGAAATGATGGCCGTGGCCGAAACCTGGGACAA
CGGCAAGGCCATCCGCGAGTGCCTGAACGCCGACCTGCCGCTGGCAGTTGACCACTTCCGCTACTTCGCCGGAGCAATCC
GCGCCCAGGAAGGTAGCCTCTCCCAGCTCGACGACGACACCACCGCATACCACTACCACGAGCCGCTGGGCGTGGTCGGG
CAGATCATCCCGTGGAACTTCCCGATCCTCATGGCCGTCTGGAAGCTCGCCCCGGCGCTGGCTGCCGGCAACGCGATCGT
GCTCAAGCCCGCCGAGCAGACCCCGGTCTCGATCCTGGTGCTCATGGAGCTGATCGGCGACCTGCTGCCAGCCGGCGTGC
TGAACGTGGTCAACGGCTTCGGCGTGGAAGCGGGCAAGCCGCTGGCATCGAACAAGCGCATCCGCAAGATCGCCTTCACC
GGCGAGACCACCACCGGCCGGCTGATCATGCAGTACGCGTCGGAAAACCTGATTCCGGTCACTCTGGAGCTGGGCGGCAA
GTCCCCGAACATCTTCTTCGAGGACATTGCCTCCAAGGACGATGCCTTCTACGACAAGGCCCAGGAAGGTTTCACCCTGT
TCGCGCTGAACCAGGGCGAGGTCTGCACCTGCCCATCGCGTGCACTGATCCAGGAAAGCATCTACGAGAAGTTCATGGGC
GATGTCGTGGCCCGCACCAAGGCCATCAAGCAGGGCCACCCGCTGGATACCGAGACCATGATGGGTGCCCAGGCCTCCAA
TGACCAGCTGGAGAAGATCCTGTCCTACATGGACATCGGCAAGTCCGAGGGCGCCAAGGTGCTGCTCGGCGGGGGACGTG
CGGATCTGGGCGGGGAACTGTCCGGCGGCTTCTACGTGCAGCCGACCATCTTCGAGGGCACTAATGACATGCGCATCTTC
CAGGAGGAGATCTTCGGTCCGGTGGTCGCGGTGACCAAGTTCAAGGACTACGACGACGCGATCTCCATCGCCAACGACAC
CCTGTACGGACTGGGTTCGGGCGTGTGGAGCCGCAATGGCAACGTCGCCTACCGTGCGGGCCGTGCCATCCAGGCCGGAC
GCGTGTGGGTCAACCAGTACCACGCCTACCCGGCGCACTCGGCCTTCGGCGGATACAAGTCCTCGGGTATCGGCCGCGAG
AACCACCTGATGATGCTGGACCACTACCAGCAGACCAAGAACCTGCTGGTTTCCTACTCGGAAGACAAGCTGGGCTTCTT
CTAG

Protein sequence :
MAVYANPNTDGALVNFKERYENYIGGQWVAPTKGMYFENVTPVTGKVFCEVARSTAEDIETALDAAHAAAPAWGKTSPAE
RAVILNKIADRIEENLEMMAVAETWDNGKAIRECLNADLPLAVDHFRYFAGAIRAQEGSLSQLDDDTTAYHYHEPLGVVG
QIIPWNFPILMAVWKLAPALAAGNAIVLKPAEQTPVSILVLMELIGDLLPAGVLNVVNGFGVEAGKPLASNKRIRKIAFT
GETTTGRLIMQYASENLIPVTLELGGKSPNIFFEDIASKDDAFYDKAQEGFTLFALNQGEVCTCPSRALIQESIYEKFMG
DVVARTKAIKQGHPLDTETMMGAQASNDQLEKILSYMDIGKSEGAKVLLGGGRADLGGELSGGFYVQPTIFEGTNDMRIF
QEEIFGPVVAVTKFKDYDDAISIANDTLYGLGSGVWSRNGNVAYRAGRAIQAGRVWVNQYHAYPAHSAFGGYKSSGIGRE
NHLMMLDHYQQTKNLLVSYSEDKLGFF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 3e-147 63
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 5e-157 63
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 5e-157 63
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 5e-157 63
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 2e-156 63

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
AARI_01370 YP_003915347.1 aldehyde dehydrogenase VFG0082 Protein 1e-147 63