Gene Information

Name : hpaE (AARI_13290)
Accession : YP_003916505.1
Strain : Arthrobacter arilaitensis Re117
Genome accession: NC_014550
Putative virulence/resistance : Unknown
Product : 5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.60
Position : 1477829 - 1479322 bp
Length : 1494 bp
Strand : -
Note : 5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase catalyzes the formation of 5-carboxymethyl-2- hydroxymuconate from 5-carboxymethyl-2-hydroxymuconate semialdehyde

DNA sequence :
ATGAGCAAGCACTTCGTACCGGAAAACCTTCCGACCCACCTGCAGCACTACATCAACGGCGAATTCGTTGACTCCATCGG
CGGAGCAACCTTCGACGTGCAGGAACCGGTCACCAACACCAACTACGCCACCGTCGCCTCGGCACAGCCTGAAGACGTGG
ATCTGGCTGTTGCCTCCGCAAACAAGGCCTTCAAGGAAGGCCCATGGTCCAAGATGCTGCCGCGCGAGCGTTCCCGCGTG
CTGCACAAGATCGCTGACATCGTCGAATCCCGCGATGAAGAGCTCTCGCTGCTCGAGTCCTACGACTCCGGCCTGCCGAT
CACCCAGGCCAAGGGCCAGGCTCGCCGCGCAGCAGAGAACTTCCGCTTCTTCGCTGACCTGATCGTCGCACAGGTGGACA
ACACCTTCCGCGTGCCAGGGCGCCAGATGAACTACGTGAACCGCAAGCCAATCGGCGTGGCCGCACTGATCACCCCATGG
AACGTTCCGTTCATGCAGGAATCCTGGAAGCTGGCTCCGGCCATCGCTACCGGAAACTCGGTAGTCCTGAAGCCTGCAAG
CTACACCCCGCTCTCCGCAGGACTGTGGCCAGAAATCTTCCGCGAGGCAGGCCTTCCAGAAGGCGTCTTCAACCTGGTCT
TCGGTTCCGGTTCCGTAGCCGGCGACTACCTGGTCAAGCACCCGGATGTGCCACTGGTTTCCTTCACCGGCGACTCCTCC
ACCGGCGCCACCATCTCCACCGCTGCAGCCCCGCAGTTCAAGGGCCTGTCCCTGGAACTGGGCGGCAAGTCTCCAGCAGT
CGTCTTCGCCGACGCTGACCTGGAAGCAGCCTTGGATGCCACCGTCTTCGGTGTCTTCTCGCTGAACGGCGAGCGTTGCA
CCGCTGGCTCCCGCGTGCTGGTACAGCGCGATATCTACGATGATTTCGTTGCCAAGTTCGCGCAGCGCGCCAAGAACATC
CGCGTTGGCCTGCCAAGCGATCCGAAGACCGAAGTCGGCGCCCTGGTGCACCCGAACCACTTCGAAAAGGTCATGAGCTA
CATCGAGATCGGCAAGACCGAAGGCCGCTTGCTGGCCGGCGGCGGCCGCGCCGAAGGCTTCGAAGAAGGCAACTACGTTG
CACCGACCGTCTTCGCAGACGTGGCACCGGATGCACAGATCTTCCAGGACGAGATCTTCGGCCCAGTTGTGGCCATCACC
CCGTTCGACACCGACGAGGAAGCACTGGAGCTGGCCAACAACACCAAGTACGGCCTGGCAGCCTACGTGTGGACTTCCAA
CCTGAAGCGTGCACACAACTTCGCGCACCAGATCGATTCGGGCATGGTGTGGCTGAACTCCAACAACGTCCGCGACCTGC
GCACCCCATTTGGCGGCGTGAAGGCTTCGGGCCTGGGACGCGAAGGCGGCTACCGCTCGGTGGACTTCTACACCACCCAG
CAGTCCATCCAGATCACCTTGAACGAAGCGCACTCCCCTAAGTTCGGCGTCTAA

Protein sequence :
MSKHFVPENLPTHLQHYINGEFVDSIGGATFDVQEPVTNTNYATVASAQPEDVDLAVASANKAFKEGPWSKMLPRERSRV
LHKIADIVESRDEELSLLESYDSGLPITQAKGQARRAAENFRFFADLIVAQVDNTFRVPGRQMNYVNRKPIGVAALITPW
NVPFMQESWKLAPAIATGNSVVLKPASYTPLSAGLWPEIFREAGLPEGVFNLVFGSGSVAGDYLVKHPDVPLVSFTGDSS
TGATISTAAAPQFKGLSLELGGKSPAVVFADADLEAALDATVFGVFSLNGERCTAGSRVLVQRDIYDDFVAKFAQRAKNI
RVGLPSDPKTEVGALVHPNHFEKVMSYIEIGKTEGRLLAGGGRAEGFEEGNYVAPTVFADVAPDAQIFQDEIFGPVVAIT
PFDTDEEALELANNTKYGLAAYVWTSNLKRAHNFAHQIDSGMVWLNSNNVRDLRTPFGGVKASGLGREGGYRSVDFYTTQ
QSIQITLNEAHSPKFGV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hpaE AAO17179.1 HpaE Not tested tcd island Protein 1e-78 44