Gene Information

Name : thrA (AARI_12590)
Accession : YP_003916438.1
Strain : Arthrobacter arilaitensis Re117
Genome accession: NC_014550
Putative virulence/resistance : Unknown
Product : homoserine dehydrogenase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0460
EC number : 1.1.1.3
Position : 1401941 - 1403227 bp
Length : 1287 bp
Strand : +
Note : catalyzes NAD-dependent reduction of aspartate 4- semialdehyde into homoserine. This reaction is the third step in a pathway leading from aspartate to homoserine. The latter participates in the biosynthesis of threonine and then isoleucine as well as in t

DNA sequence :
TTGAGCGGCGAAAAGAACCTGAAGGTAGCCCTGCTGGGTTGCGGCACCGTCGGAGCCCAAGTGGCCCGAATCCTGCTGGA
AGATGCAAATGAACTGGCTTCCCGTTCCGGGGCCGGCCTGCAACTGATCGGCATTGCGGTACGCAACCTCGATGCCAAAC
GGGATGTAGCGCTGCCCCAGGAGCTTTTCACCACCGACGCCCACGGGCTGATTGCCCAGGCCGATGTGGTGATCGAGCTG
CTCGGCGGCCTTGAGCCTGCTGGCGAATACATCGCCGCGGCCCTGTCCAAGGGCGCGAGCGTCATCACCGGCAACAAGGC
GCTGATCGCCCTTGAAGGCGCCAAGCTCAACGAGATCGCCGCCGCCAATGGCGCGCAGCTACGCTACGAGGCCGCAGTGG
CCGGGGCCATCCCGATCCTGCGCCCGATCGCCGACTCGCTGGCAGGGGACCGCATCACCAAGGTGATGGGCATCGTCAAC
GGCACCACCAACTTCATCCTCGACGCGATGGACACCACCGGTGCTGCCTTCGACGACGTGCTGGCCGAAGCCCAGGCGCT
GGGCTACGCCGAAGCTGATCCAACCGCCGACGTGGGCGGGCACGATGCCGCCGCGAAGGCCGCGATCCTCGCATCCTTGG
CTTTCCACACCAACGTCTCCTCCGACCAGGTGTCCACCGAAGGCATCACCGAGGTCACTGCCGCGGATGTGTCCGCAGCG
GCGGCAGCCGGCTACGTCATCAAGCTGCTGGCCATTGCCGAGCAGGCCGAAGCGGGCATTTCGGTGCGCGTCTACCCGGC
CCTGGTGCGCCGCAGCCACCCATTGGCCACCGTGCATGGCGCGTTCAACGCCGTGTTCGTGGAGGCGGAGAATGCCGGGG
ATTTGATGTTCTACGGCGCCGGTGCCGGCGGCAACGCCACCGCCTCGGCCGTGATGGGCGATGTGGTTTCCGTGGCTCGG
CAGATCGCTGCCGGTGCCCCGCTGCCCAACGGCTCGATCAACCAGGCGCCAACGCTGCTGGACTTCGAGGCGATCACCAC
CCGCTACTGGATTGGCCTGTCGGTCAAGGACCAGTCCGGCGTGCTGGCCGCCATCGCCACCGTCTTCGGCGAGCATGGGG
TCTCCATCGAGTCGATGAGCCAGCAGGTGGACGCCGAAGCCGGCGCGCAGTTGCGCATTCTGACCCACCAGGGCACCGAA
GCGGCCCTGGCCAGCACCGTCGAAGCGCTCAAGGCGCTGGACGCGGTGCACTCAGTCTTATCCGTTATGCGAGTTGAAGG
AAACTAA

Protein sequence :
MSGEKNLKVALLGCGTVGAQVARILLEDANELASRSGAGLQLIGIAVRNLDAKRDVALPQELFTTDAHGLIAQADVVIEL
LGGLEPAGEYIAAALSKGASVITGNKALIALEGAKLNEIAAANGAQLRYEAAVAGAIPILRPIADSLAGDRITKVMGIVN
GTTNFILDAMDTTGAAFDDVLAEAQALGYAEADPTADVGGHDAAAKAAILASLAFHTNVSSDQVSTEGITEVTAADVSAA
AAAGYVIKLLAIAEQAEAGISVRVYPALVRRSHPLATVHGAFNAVFVEAENAGDLMFYGAGAGGNATASAVMGDVVSVAR
QIAAGAPLPNGSINQAPTLLDFEAITTRYWIGLSVKDQSGVLAAIATVFGEHGVSIESMSQQVDAEAGAQLRILTHQGTE
AALASTVEALKALDAVHSVLSVMRVEGN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB0868_00309 YP_008211635.1 Homoserine dehydrogenase Not tested AbaR26 Protein 6e-53 42
BJAB07104_00305 YP_008207770.1 Homoserine dehydrogenase Not tested AbaR25 Protein 6e-53 42