Gene Information

Name : clpC (AARI_01020)
Accession : YP_003915312.1
Strain : Arthrobacter arilaitensis Re117
Genome accession: NC_014550
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease ATP-binding subunit
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 110617 - 113139 bp
Length : 2523 bp
Strand : +
Note : ATP-dependent Clp proteases act as chaperones to target the proteases to substrates

DNA sequence :
GTGCCGAAGATGTTTGAGAGATTTACCGACCGTGCCCGTCGAGTTGTCGTGCTCGCCCAAGAAGAGGCGCGCATGCTCAA
CCACAATTACATCGGCACCGAGCACCTGCTGCTCGGTCTAATCCACGAAGGTGACGGTGTTGCCGCAAAGGCACTCGAGT
CGCTGAATATTTCGTTGGGTGCCGTGCGTGAGCAGGTTCAGGAGATTATCGGCAAGGGCCAGCAGGCGCCTTCCGGTCAT
ATCCCGTTCACTCCTCGCGCCAAGAAAGTTTTGGAGCTCTCGCTGCGTGAAGCGCTGCAGCTGGGACATAACTACATTGG
TACCGAGCACATCCTGCTCGGCCTGATCCGCGAAGGCGAAGGCGTCGCAGCCCAGGTTCTGGTGAAGCTGGGTGCTGACC
TCGGTCGCGTGCGCCAGCAGGTCATCCAGCTGCTCTCGGGCTACCAGGGCGGCAAGGAAACTGCCTCCGCCGGCGTCAGC
TCGGGCGGCCAGCAGGAGGGCACCCCAGCGGGTTCCGCCGTGCTGGACCAGTTCGGTCGAAACCTCACCGCAGCTGCCCG
TGAAGGCAAGCTCGATCCGGTGATTGGCCGCGAGCACGAGATGGAACGCGTTATGCAGGTCCTCTCGCGCCGTACCAAGA
ACAACCCTGTTCTGATTGGTGAGCCTGGCGTTGGCAAGACCGCAGTCGTCGAAGGCTTGGCCCAGTCGATCGTGCGCGGC
GATGTACCGGAAACCATCAAGGACAAGCAGCTGTACACCTTGGACCTCGGTTCACTGGTTGCAGGTTCGCGCTACCGCGG
TGACTTCGAGGAACGCCTGAAGAAGGTCTTGAAGGAAATCCGTACCCGTGGCGACATCATCTTGTTCATCGATGAGATCC
ACACCCTGGTAGGTGCCGGTGCGGCCGAAGGCGCTATCGATGCTGCTTCGATCCTCAAGCCAATGCTGGCTCGTGGCGAA
CTGCAGACCATCGGTGCGACCACCTTGGACGAGTACCGCAAGAACATTGAGAAGGATGCAGCGCTCGAGCGCCGCTTCCA
GCCAATCCAGGTCAAGGAGCCTTCGGTTGAGCTGACCACGCAGATCCTGCGTGGCCTGCGTGACCGCTACGAGGCGCACC
ACCGCGTGACCATCACTGATGGCGCGCTGCAGGCTGCCGCCACCTTGGCGCATCGCTATATCTCTGATCGCTTCCTGCCG
GATAAGGCAGTGGACCTGATCGATGAGGCCGGTGCCCGACTGCGCATCCAGCGCATGACCGCTCCTCCTGCCCTGAAGGA
AATGGACGAGGAAATCGCCACCGTGCGCTTGGAGAAGGAAGCTGCGATTGACGCGCAGGACTTCGAAGGTGCCGCATCGC
TGCGTGACAAGGAATCCAAGCTCATCGAGGCTCGTAACGAGAAGGAGAAGTCCTGGCGCAATGGCGACATGGACGAGGTC
TCCGAGGTGACCGAGGAACTCATCGCCGAAGTCTTGGCTAACTCCACCGGCATCCCGGTAGTGAAGCTGACCGAGGAAGA
GTCCTCGCGACTGCTGAACATGGAAGATGAGCTGCACAAGCGCGTTATCGGCCAGGATTCAGCGATCAAGGCCATCTCCC
AGGCGATCCGCCGTACCCGTGCAGGCCTGAAAGATCCGAACCGCCCAGGCGGCTCGTTCATCTTCGCCGGCCCAACCGGC
GTAGGCAAGACTGAGCTGGCCAAGGCGCTGGCAGAGTTCCTGTTCGGTGAAGAAGAGGCACTGATCACCCTGGATATGTC
CGAATACTCGGAGAAGCACACCGTTTCCCGTCTGTTCGGTGCCCCTCCGGGCTACGTCGGCTACGAAGAAGGCGGACAGC
TGACCGAGAAGGTTCGCCGCCGTCCATTCTCCGTCGTGCTCTTCGATGAGGTCGAGAAGGCCCACGCTGACCTGTTCAAC
TCGTTGCTGCAGATCCTGGAAGACGGCCGCCTGACCGACTCCCAGGGCCGCGTGGTGGACTTCAAGAACACCATCATCAT
CATGACCACCAACCTCGGTACCCGCGACATCTCCAAGGGTGTGATGACCGGCTTCCAGTCGGCCGCGGATACCAAGACCG
GTTATGAGCGCATGCAGGCCAAGGTCCAGGAAGAACTGCGTCAGCATTTCCGCCCTGAATTCTTGAACCGCGTTGATGAC
ACCGTCGTCTTCCCGCAGCTGAACCAGGACGAGATCGAAGAGATCGTCGACTTGTTCGTCGCCCGTCTGGCCAAGCGCCT
GAAGGATCGCGATATGACCATCGAGCTGACTCAGGCTGCACGCAGCCTGCTGGCACAGCGCGGCTACGACCCAGCCATGG
GTGCCCGTCCGCTGCGCCGTACCATCCAGCGCGATATCGAAGATCAGCTCTCCGAGCGGATCCTCTTCGGGCAGATCGTT
GCCGGACAGAAGATCACCGTGGACGTCGAAGGCGAAGGCGAGCTGCAGAAGTTCGTCTTCCACGCCGAGGGCGGCACCGG
CCAGCTGGAAGGCGAGCCGGCACCGGCTGCGTTGGAAAGCTAG

Protein sequence :
MPKMFERFTDRARRVVVLAQEEARMLNHNYIGTEHLLLGLIHEGDGVAAKALESLNISLGAVREQVQEIIGKGQQAPSGH
IPFTPRAKKVLELSLREALQLGHNYIGTEHILLGLIREGEGVAAQVLVKLGADLGRVRQQVIQLLSGYQGGKETASAGVS
SGGQQEGTPAGSAVLDQFGRNLTAAAREGKLDPVIGREHEMERVMQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQSIVRG
DVPETIKDKQLYTLDLGSLVAGSRYRGDFEERLKKVLKEIRTRGDIILFIDEIHTLVGAGAAEGAIDAASILKPMLARGE
LQTIGATTLDEYRKNIEKDAALERRFQPIQVKEPSVELTTQILRGLRDRYEAHHRVTITDGALQAAATLAHRYISDRFLP
DKAVDLIDEAGARLRIQRMTAPPALKEMDEEIATVRLEKEAAIDAQDFEGAASLRDKESKLIEARNEKEKSWRNGDMDEV
SEVTEELIAEVLANSTGIPVVKLTEEESSRLLNMEDELHKRVIGQDSAIKAISQAIRRTRAGLKDPNRPGGSFIFAGPTG
VGKTELAKALAEFLFGEEEALITLDMSEYSEKHTVSRLFGAPPGYVGYEEGGQLTEKVRRRPFSVVLFDEVEKAHADLFN
SLLQILEDGRLTDSQGRVVDFKNTIIIMTTNLGTRDISKGVMTGFQSAADTKTGYERMQAKVQEELRQHFRPEFLNRVDD
TVVFPQLNQDEIEEIVDLFVARLAKRLKDRDMTIELTQAARSLLAQRGYDPAMGARPLRRTIQRDIEDQLSERILFGQIV
AGQKITVDVEGEGELQKFVFHAEGGTGQLEGEPAPAALES

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 74
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 3e-94 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpC YP_003915312.1 ATP-dependent Clp protease ATP-binding subunit VFG0079 Protein 0.0 61
clpC YP_003915312.1 ATP-dependent Clp protease ATP-binding subunit VFG0080 Protein 3e-145 52