Gene Information

Name : Fbal_2178 (Fbal_2178)
Accession : YP_003913455.1
Strain : Ferrimonas balearica DSM 9799
Genome accession: NC_014541
Putative virulence/resistance : Resistance
Product : acriflavin resistance protein
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0841
EC number : -
Position : 2426819 - 2429911 bp
Length : 3093 bp
Strand : +
Note : COGs: COG0841 Cation/multidrug efflux pump; InterPro IPR001036; KEGG: vha:VIBHAR_05963 hypothetical protein; PFAM: acriflavin resistance protein; SPTR: A3UXK2 transporter, AcrB/D/F family; PFAM: AcrB/AcrD/AcrF family

DNA sequence :
ATGAACATTGCGCAATACGCGATTAAACACCGGGTGATCAGCTGGATGTTCCTGATCATTCTCGCCATCGGCGGCGTGCT
GGCGTTCCAGGATCTCGGTCGTCTTGAAGACCCCGCCTTTACCATCAAGGATGCCATGGTGATCACCCAATACCCGGGTG
CCACCGCCATGGAGGTGGAGGAGGAGCTGACCTACCCGCTGGAAAAGGCGATCCGCCAACTGCCCTACGTCGACAAGATC
AACTCCACCTCAACGCCGGGCATGTCACAGATCATGGTCAGCATGAAGATGGACTACGGCGCCGATGAGCTGCCGCAGAT
CTGGGACGAGCTGCGCCGCAAAGTCGCCGACGAGCAACCCATGCTGCCGCCGGGCGCCTATCCCCCCAAGGTGATGGACG
ACTTTGGCGACGTGTTTGGCATCCTGCTGATGGTGACCGGCGACAACTACAGCTACAGCGAACTCAAAGAGTACGTGGAC
TACATGCGCCGCGAGCTGGAGCTGGTGGACGGCGTCGGCAAAGTGGCGCTGGCGGGCGACCAGCAGGAACAGATCCACAT
CGAGATCTCGCTGAAGAAACTGGCCGCGCTGAACCTGGACGTCAACACTGTAGTGGGCCTGCTGAACCAACAGAACGCGG
TACTGGACGCCGGTAAGATCACCATCGACGGTGAGTCCCTCTACCTGCGCCCCGGCGGCTTTGACTCCAGCGTTGACCCC
ATCATTCACGGCCGCGATACCGGCCAGTTGGTGCGCCTGACCGACGTGGCCACCATCCACCGCGGCTTTCAGGAGATCCC
CACCAACCTGGTGCAGTACAACGGCGACAGCGCCATCAGCCTCGGCATCAGCTTTGCCACCGGAGTGAACGTGGTGGAAG
TGGGCCAGCGCATCGACGCAGTACTGGCAGAACTGGAATCCGCCAAACCCGCGGGGATCCACCTGCACACCCTCTACGAC
CAGCCCAAAGAGGTCGACCAATCGGTCAACGGCTTTATCATCAGCCTGGCTGAAGCGGTGGGCATCGTCATCGTGGTGCT
GCTGTTTGCCATGGGGCTGCGCAGCGGCCTGATCATCGGCCTGGTGCTGCTGCTGACCGTGCTCGGCACCTTTATGATGA
TGCAGTGGACCAACGTGGAGCTGCACCGCATCTCCCTCGGGGCACTGATCATCGCGCTGGGGATGCTGGTGGACAACGCC
ATCGTGGTGGTGGAAGGCATTCTGGTGGGCCGCCAGCGCGGCCTGTCCAAGCTGGAATCGGCCACCGCCATCGTCAGGCA
GACCGCCTGGCCACTGCTCGGTGCCACGGTGATCGCCATCACCGCCTTTGCCCCCATTGGCCTCTCTCCGGATGCCACCG
GGGAGTTTATGGGCTCACTGTTCTGGGTGCTGTGTTACTCGCTGTTCCTGAGCTGGATCACCGCCCTGACCCTCACCCCC
TTCCTGGCCGATCTGCTGATGCCGGCAACGGACAGCAAGAGCGATAACACCGATGCGGCGGATCCCTATCAGGGCTTTAT
CTTTACGCTGTTCCGGGGTTCCCTGCGCTTCGCGCTGCGCTACAAAGCCCTGACTCTGGGCGCCATGCTGCTGTTGCTGG
TGGGCGCCGGGGCGGGCTTCGGCTTGGTGAAAAACGCCTTCTTCCCGCCCTCCAATACGCCGATTTTCTACCTCGACCTG
TGGATGCCGGAGGGCACCGACATCCGCACCACCCATCAAACCGTGCAGGCGGTGGAAGCCACCATCCTTGATAAACCCGG
AGTGGACTTCGTCACCTCCACCACCGGCCAGGGGATGCAACGCTTTACCCTCACCTACCAGCCGGAGAAACAGTACGCCG
CTTTCGCCCAGTTGCAGGTGCGCACCGACACTCGTGAACGGATGCAGGGGCTGATGCGGGAACTGGATACCGAGTTGTCG
CAACGGTTCCCGCAGGCGCAGTTCCAGCAGCGCCTGATGGAGATCGGCCCGTCACCGGCCTCGAAGATTGAAGCCCGCCT
GAGCGGCCCGGATCCGGATACCCTGCGCACCCTGGCCAGCCAGGTGGAGACGGTGTTCCGGGCCGATGCTGGCGCCCGCA
ATGTGCGCCACAACTGGCGCGAACGTACCAAGGTGCTGGTGCCGGTGATCAACGAGTCCCAGGCCCGACGACTCGGCATC
AGCAACGAAGAGCTGGCCGGTACCCTGCAGATGGCCTTTGGCGGCACCCAGGTGGGGCTGTACCGCGACGGCACCCGGAT
GCTGCCCATCGTGGTGCGCCTGCCGGAAGCGGAGCGGGTCGATTTCGGCAGCTTCGACAACATCACCATCTGGAGCCCGA
CCCTGCAGACCTACGTACCGGTCCAGCAGGTGGTCAGCCGGGTTGATCTGGTGTGGCAGGATTCGGTGATTCAGCGTAAG
GATCGCAAACGCACCCTGACGGTAATGGCGGACCACGACATTCTCGGCGACGAAACCGCCGCCAGCCTGTTCAACCGATT
GCGCCCGCAGGTAGAGGCGATCAGCCTGCCGCCGGGTTACAGCCTTGAGTGGGGCGGCGAGTTTGAAGCCCAGAACGACG
CCCAGAGCATGCTGTTCAGCTCACTGCCGATGGGCTACCTGTTTATGTTCATCATCACGGTGTTCCTGTTCGATTCCCTG
CGCAAGCCGGTGGTGATCTGGCTGACGGTGCCGCTGTCGGTCATTGGCGTGACCGTGGGGCTACTGGTGACCAACCAGCC
CTTCACCTTTACCGCCTTGCTGGGCTTGCTGTCGCTGAGCGGGATGGTACTGAAGAACGGCATTGTGTTGCTGGACCAGC
TCAATCTGGAGCTGGCTTCAGGCAAGCGCCCCTATGACGCGGTAATGGACGCCGCCATCAGCCGGGTCCGGCCGGTGAGC
ATGGCCGCGCTGACCACCATCCTGGGGATGATCCCACTGGTGTTCGACGCCTTCTTTGCCTCCATGGCGGTGACCATCAT
GTTTGGCCTTGGCTTTGCAACGGTTCTGACCCTGGTGGTGGTGCCGGTGTTGTACGCCACCTTCTACCGCATCGCCCCAC
CCGCAAAGGAAGCGCAGCCAGAACCGACCCCGCTTCAGCCGGTGGCCGCCTAA

Protein sequence :
MNIAQYAIKHRVISWMFLIILAIGGVLAFQDLGRLEDPAFTIKDAMVITQYPGATAMEVEEELTYPLEKAIRQLPYVDKI
NSTSTPGMSQIMVSMKMDYGADELPQIWDELRRKVADEQPMLPPGAYPPKVMDDFGDVFGILLMVTGDNYSYSELKEYVD
YMRRELELVDGVGKVALAGDQQEQIHIEISLKKLAALNLDVNTVVGLLNQQNAVLDAGKITIDGESLYLRPGGFDSSVDP
IIHGRDTGQLVRLTDVATIHRGFQEIPTNLVQYNGDSAISLGISFATGVNVVEVGQRIDAVLAELESAKPAGIHLHTLYD
QPKEVDQSVNGFIISLAEAVGIVIVVLLFAMGLRSGLIIGLVLLLTVLGTFMMMQWTNVELHRISLGALIIALGMLVDNA
IVVVEGILVGRQRGLSKLESATAIVRQTAWPLLGATVIAITAFAPIGLSPDATGEFMGSLFWVLCYSLFLSWITALTLTP
FLADLLMPATDSKSDNTDAADPYQGFIFTLFRGSLRFALRYKALTLGAMLLLLVGAGAGFGLVKNAFFPPSNTPIFYLDL
WMPEGTDIRTTHQTVQAVEATILDKPGVDFVTSTTGQGMQRFTLTYQPEKQYAAFAQLQVRTDTRERMQGLMRELDTELS
QRFPQAQFQQRLMEIGPSPASKIEARLSGPDPDTLRTLASQVETVFRADAGARNVRHNWRERTKVLVPVINESQARRLGI
SNEELAGTLQMAFGGTQVGLYRDGTRMLPIVVRLPEAERVDFGSFDNITIWSPTLQTYVPVQQVVSRVDLVWQDSVIQRK
DRKRTLTVMADHDILGDETAASLFNRLRPQVEAISLPPGYSLEWGGEFEAQNDAQSMLFSSLPMGYLFMFIITVFLFDSL
RKPVVIWLTVPLSVIGVTVGLLVTNQPFTFTALLGLLSLSGMVLKNGIVLLDQLNLELASGKRPYDAVMDAAISRVRPVS
MAALTTILGMIPLVFDAFFASMAVTIMFGLGFATVLTLVVVPVLYATFYRIAPPAKEAQPEPTPLQPVAA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0395_A1355 YP_001217299.1 AcrB/AcrD/AcrF family transporter Not tested VPI-2 Protein 7e-180 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Fbal_2178 YP_003913455.1 acriflavin resistance protein BAC0526 Protein 0.0 67
Fbal_2178 YP_003913455.1 acriflavin resistance protein BAC0428 Protein 0.0 60
Fbal_2178 YP_003913455.1 acriflavin resistance protein BAC0519 Protein 0.0 59
Fbal_2178 YP_003913455.1 acriflavin resistance protein BAC0425 Protein 3e-180 43