Gene Information

Name : Thet_1715 (Thet_1715)
Accession : YP_003904587.1
Strain : Thermoanaerobacter sp. X513
Genome accession: NC_014538
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.9.2
Position : 1679680 - 1681431 bp
Length : 1752 bp
Strand : -
Note : TIGRFAM: pyruvate kinase; KEGG: tpd:Teth39_0684 pyruvate kinase, pyruvate, water dikinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PEP-utilising protein mobile region

DNA sequence :
ATGCGCAGAACAAAAATAGTGTGTACAATAGGACCTGCCAGCGAAGACTATAATATACTGAGAAAATTAATTGAGAAAGG
TATGAACGTTGCTCGATTGAATTTTTCTCATGGGGATTTTGAAGAGCATGGGGCAAGAATTGACAATATTAAAAAGATAA
GAGAAGAATTCGGGCTACCTGTTGCTATTTTGTTGGATACTAAAGGTCCAGAGATAAGGACAGGAAAGTTTAAAAATGGC
GGAGTGGAATTAAAAGAAGGACAAACTTTTGTCATTACGACAAGAGATGTATTAGGAGACGAAACTATATGCAGTGTATC
CTATAAAGGGTTGCCTCAAGATGTGGAAAGAGGTAGCCGCATACTAATTGACGATGGGTTAATTTCTCTAAAGGTTACTG
ATGTTAAAGGAGAAGATATAGTTTGTATTGTAGAAAATTCTGGTCCTGTAAAAGACCATAAAGGAGTAAATGTTCCAGGA
GTAAAACTCAATCTTCCTGCTTTGACTCAAAAAGACGTAGATGATATAGAGTTTGGAATTCAAAAGGGCATTGATATAAT
TGCGGCTTCTTTTGTTAGAAAAGCAGCTGATGTTTTGGCAATAAGAAGACTTTTAGAAGAAAATAAGGCAGAGCATATTT
TAATTATTGCTAAAATAGAAAATCGCGAAGGAGTAGAAAATATAGACGAAATTATAAAGGTTTCAGATGGAATAATGGTA
GCCAGAGGAGATTTAGGGGTTGAGATTCCTCTTGAAGAAATACCAATCGTTCAAAAGATGATTATACAAAAATGTAATAA
AGCAGGGAAACCGGTAATTACTGCAACTCAAATGTTAGACTCTATGATGAGAAATCCAAGGCCTACAAGAGCAGAAGTTA
CAGATGTAGCAAACGCTATTCTAGATGGGACAGATGCTATAATGCTATCAGGGGAGACAGCTCAAGGTAAATACCCCATA
GAGGCCTTTGAGACAATGGCAAAGATTGCAGAAAAGACAGAAGCTTATGTGGGATACAGAGATATCATTGATAGAAATAT
TGATACAAATGTTTCTATTACAAACGCTATAAGCCATGCAACTTGTACTACTGCAAGAGATATAGGTGCAGCTGCTATAA
TAACTTGTACTAAATCTGGCTATACAGCGAGAATGGTATCAAGGTACAGACCTCAAGCTCCGATTATTGCTACTACTCCA
AGCGAAAGTGTTGCAAGGAAACTCTCTATAGTCTGGGGAGTATATCCTTTGATTACAGAAGAGGTTTCTACTACAGATGA
AATGATAGATGTCGCAATACAAAGTGCTTTAACTGCAGGACTTATAAGAAATGGTGATATCGTAGTAATTTCTGCAGGAA
TTCCTGTAGCTATGACAGGCACCACCAACATGTTGAAGGTACATATAGTAGGAGATGTTTTGTTGAGAGGAATAGGTATA
GGTTCTAAGGCTACTACAGGTGTTGTATGTGTTATTAATGATATCAGCAAAGACAAAGATAAATTTAGAGAAGGCGATAT
AATAGTAACTGCAAAGACAGAAAGAGATTTTATGCCTCTTATAGAGAAAGCTTCTGCTATAATCACAGAAGAAGGAGGGC
TTACTTCTCACGCAGCTATTGTGGGATTAAACTTAGGAATTCCTGTAGTTGTAGGTTGTGAAGGAGCGACTTCTAAATTA
AAAGATGGCATGACTGTAACGGTTGACACAGTTAGAGGATTTGTGTATAAAGGAATTGTAAATATTAAATAA

Protein sequence :
MRRTKIVCTIGPASEDYNILRKLIEKGMNVARLNFSHGDFEEHGARIDNIKKIREEFGLPVAILLDTKGPEIRTGKFKNG
GVELKEGQTFVITTRDVLGDETICSVSYKGLPQDVERGSRILIDDGLISLKVTDVKGEDIVCIVENSGPVKDHKGVNVPG
VKLNLPALTQKDVDDIEFGIQKGIDIIAASFVRKAADVLAIRRLLEENKAEHILIIAKIENREGVENIDEIIKVSDGIMV
ARGDLGVEIPLEEIPIVQKMIIQKCNKAGKPVITATQMLDSMMRNPRPTRAEVTDVANAILDGTDAIMLSGETAQGKYPI
EAFETMAKIAEKTEAYVGYRDIIDRNIDTNVSITNAISHATCTTARDIGAAAIITCTKSGYTARMVSRYRPQAPIIATTP
SESVARKLSIVWGVYPLITEEVSTTDEMIDVAIQSALTAGLIRNGDIVVISAGIPVAMTGTTNMLKVHIVGDVLLRGIGI
GSKATTGVVCVINDISKDKDKFREGDIIVTAKTERDFMPLIEKASAIITEEGGLTSHAAIVGLNLGIPVVVGCEGATSKL
KDGMTVTVDTVRGFVYKGIVNIK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 3e-106 51
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 2e-106 51
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 2e-106 51
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 8e-106 51

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Thet_1715 YP_003904587.1 pyruvate kinase VFG0479 Protein 8e-107 51