Gene Information

Name : guaA (HELO_1630)
Accession : YP_003896699.1
Strain : Halomonas elongata DSM 2581
Genome accession: NC_014532
Putative virulence/resistance : Unknown
Product : bifunctional GMP synthase/glutamine amidotransferase protein
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 726100 - 727869 bp
Length : 1770 bp
Strand : +
Note : GMP synthase [glutamine-hydrolyzing] - Pseudomonas putida (strain KT2440),InterPro: GMP synthase C-terminal, High confidence in function and specificity

DNA sequence :
ATGAATCCCACGTCCACGACGTGCAGATCACCAAGGAAGCGCCCAACTACAGAGCGGGCTAATGCCCGTTTGAGACGGAA
GAGGGAAGGGAGAAGCAGGAAGGGACCCCTTCCTCTTCACTCTTTCCTCTTATTCTTTATCCGGCAGTGCCTTTGTCTGG
GTACTCGAATTCATTACGGCGGTGGCCCCTCCATGACCGACATTCATGCCCACAAGATCCTGATCCTCGATTTTGGCTCC
CAGTACACCCAGTTGATCGCCCGCCGGGTGCGCGAGATTGGCGTCTACTCTGAAGTGCGTGCCTTCGATATCACCGAGGA
CGAGATTCGCGCCTACAACCCCAACGGCATCATCCTCGCCGGTGGCCCGGAATCCGTCACCGAGCTCGACTCTCCCCGTG
CGCCGCAATGCGTCTTCGAGATGGGCTTGCCGGTGCTGGGTATCTGCTACGGTATGCAGACCATGGCCGAGCAGCTCGGC
GGCGGCGTGGAAGGTTCGCAGAAGCGTGAATTCGGCTATGCACAGATTCGCCTCGACGGCGAGAGTGCCCTGTTCGAGGA
CATCGCCGACCATATCGAGGATGAGAGTGGCAAGCGCCTGCTCGATGTGTGGATGAGCCACGGCGACAAGGTCGCCCGGG
TACCGGAGGCCTTCAGCGTGATCGCCTCCACCGAGAGCTGCCCGATCGCCGCCATGGCCTGGGAGGAGAAGCGCTTCTAT
GGCGTGCAGTTCCACCCCGAGGTGACGCATACCCTGCAGGGGCAGCGCATTCTCGAGCACTTCGTGCTGGGCATCTGCCA
GGCGGAGCGCTGGTGGACGCCGGCGCAGATCATCGAGGACCAGGTCGCCCGGGTTCGTGAACAGGTGGGCGACCGCCACG
TGCTGCTGGGGCTTTCCGGCGGTGTCGACTCCTCGGTGGTGGCCGCGCTGTTGCACAGGGCCATCGGCGACCAACTGACC
TGCGTGTTCGTCGACAACGGCCTGCTGCGCAAGGACGAAGGCGATCAGGTGATGAAGACCTTCTCCAGCCACATGGGTGT
GCGGGTGATCCGCGTCGACGCCGAGGAGCAGTTCCTGTCGCGCCTCGAGGACGTGCATGACCCCGAGGCCAAGCGCAAGA
TCATCGGCAACACCTTCATCGACGTATTCGATGCCGAGGCAGCCAAGATCGAGGGCGTGGAATTCCTCGCCCAGGGCACC
ATCTACCCGGATGTGATCGAATCCGCCGCCGCCAAGACCGGCAAGGCGCACGTCATCAAGTCTCACCACAACGTGGGCGG
CCTGCCCGAGACCATGAAGCTGCAGCTCGTCGAGCCCCTGCGCGAGCTGTTCAAGGACGAGGTGCGCAAGCTCGGTGTCG
AGCTCGGCCTGCCCTACGACATGGTCTATCGTCACCCCTTCCCGGGGCCGGGGCTCGGCGTGCGCATCCTCGGCGAGGTG
AAGAAGGAATACGCCGACATCCTGCGCGAGGCCGACGCCATCTTCATCGAGGAACTGCACAAGGCCGACTGGTACCACAA
GACCAGCCAGGCCTTCGCCGTCTTCCTGCCGGTGAAATCCGTCGGCGTGGTCGGCGACGGTCGCCGCTACGAATGGGTCA
TCGCCCTGCGCGCCGTGGAGACCATCGACTTCATGACCGCCCGCTGGGCACACCTGCCCTACGAGCTGCTGGAAACCGTC
TCCAACCGCATCATCAACGAGCTGGAAGGCGTCTCCCGCGTTACCTATGACGTGAGCAGCAAGCCGCCCGCGACCATCGA
GTGGGAGTGA

Protein sequence :
MNPTSTTCRSPRKRPTTERANARLRRKREGRSRKGPLPLHSFLLFFIRQCLCLGTRIHYGGGPSMTDIHAHKILILDFGS
QYTQLIARRVREIGVYSEVRAFDITEDEIRAYNPNGIILAGGPESVTELDSPRAPQCVFEMGLPVLGICYGMQTMAEQLG
GGVEGSQKREFGYAQIRLDGESALFEDIADHIEDESGKRLLDVWMSHGDKVARVPEAFSVIASTESCPIAAMAWEEKRFY
GVQFHPEVTHTLQGQRILEHFVLGICQAERWWTPAQIIEDQVARVREQVGDRHVLLGLSGGVDSSVVAALLHRAIGDQLT
CVFVDNGLLRKDEGDQVMKTFSSHMGVRVIRVDAEEQFLSRLEDVHDPEAKRKIIGNTFIDVFDAEAAKIEGVEFLAQGT
IYPDVIESAAAKTGKAHVIKSHHNVGGLPETMKLQLVEPLRELFKDEVRKLGVELGLPYDMVYRHPFPGPGLGVRILGEV
KKEYADILREADAIFIEELHKADWYHKTSQAFAVFLPVKSVGVVGDGRRYEWVIALRAVETIDFMTARWAHLPYELLETV
SNRIINELEGVSRVTYDVSSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 6e-127 53
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 4e-127 53
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 3e-127 53
guaA NP_938969.1 GMP synthase Not tested Not named Protein 5e-116 51