Gene Information

Name : cadR (HELO_1543)
Accession : YP_003896611.1
Strain : Halomonas elongata DSM 2581
Genome accession: NC_014532
Putative virulence/resistance : Resistance
Product : Cd(II)/Pb(II)-responsive transcriptional regulator
Function : -
COG functional category : K : Transcription
COG ID : COG0789
EC number : -
Position : 626398 - 626850 bp
Length : 453 bp
Strand : +
Note : HTH-type transcriptional regulator hmrR -Sinorhizobium medicae (strain WSM419) (Ensifer medicae),InterPro: Bacterial regulatory protein MerR family, High confidence in function and specificity

DNA sequence : 
ATGAAGATCGGTGAGCTGGCGACTCGCACGGGATGTCGGGTCGTGACCATTCGCTACTACGAGCGGGAAGGCCTGCTGCC
CGAGCCGGCACGCAGCGAGGCCAATTACCGTCTCTACGGCGAGACCCACGTCGAGCGCCTGGCCTTCATTCGCCACTGCC
GGGCGCTGGACATGACGCTGGACGAGATCCGCGCCTTGCTGGACTGCCATGACCATCCGGCGCAGTCCTGCCAACGGGCC
AATGTCCTGATCGATGAGCACCTGAGCCATGTGGAAGCACGTATCGCCCAGCTTCAGGCCCTGGAAGAAACGCTGGTGGC
GCTGCGGGCCCGTTGCCAGGGGCAGCGCCCGGCCGCCGAGTGCGGCATCCTCAATGCCCTGGCGCAGCCGCCGCGGGACG
AGCCATTGAATGAGGACGCCGAACACGTACCCGGTACGCATCCCCGCCTCTGA

Protein sequence : 
MKIGELATRTGCRVVTIRYYEREGLLPEPARSEANYRLYGETHVERLAFIRHCRALDMTLDEIRALLDCHDHPAQSCQRA
NVLIDEHLSHVEARIAQLQALEETLVALRARCQGQRPAAECGILNALAQPPRDEPLNEDAEHVPGTHPRL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ORF C98 AAN62191.1 putative transcriptional regulator Not tested PAGI-2(C) Protein 3e-35 55
cadR ADZ05769.1 MerR family transcriptional regulator Not tested AbaR11 Protein 2e-34 52
cadR ACS32041.1 MerR family transcriptional regulator Not tested AbaR5 Protein 4e-34 52
ACICU_00234 YP_001844893.1 transcriptional regulator Not tested AbaR20 Protein 3e-34 52
pbrR CAJ77021.1 transcription regulator Not tested AbaR1 Protein 2e-34 52
pbrR CAJ77094.1 Transcriptional regulator Not tested AbaR1 Protein 2e-34 52
cadR AGK36653.1 MerR family transcriptional regulator Not tested AbaR26 Protein 2e-34 52
cadR ACN81029.1 MerR family transcriptional regulator Not tested AbaR5 Protein 3e-34 52

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
cadR YP_003896611.1 Cd(II)/Pb(II)-responsive transcriptional regulator BAC0058 Protein 3e-38 59
cadR YP_003896611.1 Cd(II)/Pb(II)-responsive transcriptional regulator BAC0301 Protein 4e-33 59