Gene Information

Name : cadA (HELO_1542)
Accession : YP_003896610.1
Strain : Halomonas elongata DSM 2581
Genome accession: NC_014532
Putative virulence/resistance : Resistance
Product : membrane transport ATPase
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG2217
EC number : 3.6.1.-
Position : 624108 - 626306 bp
Length : 2199 bp
Strand : -
Note : Copper-transporting P-type ATPase copA - Bacillus subtilis,InterPro: Heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase, High confidence in function and specificity

DNA sequence :
ATGTCCGATGCCCATGAACATGGCTGCTGCGGCGGCCATCACACCGAGCCTCGCGAGGCCGTGGCCGCCCCGGCGGACAG
CGAGACGCTGCGCCTGCGCATCCAGGAGATGGACTGCCCCACCGAGGAAGCCCTGCTGCGCAAGGCCCTGACCTCGGCGC
CCGGCGTCGCTGCCCTGGAATTCGACCTGATGGCCAGGATACTCAGCATCCACCATCACGACGCCGATACCGAGGCACTT
CAGGCACGCGTTCGCGACCTGGGCATGACGCCTCGCCCGCTGGATACCGATGACGACCCGAGCGACGAGCCGCCGGCAAG
CGACGACACGCCCTGGGGGCGGCTGATACTGGCAGCCCTCCTGGCCCTGGCCGCCGAGATCGTCGGCTGGACGCCCTGGC
CCTGGACCGACTGGCTGGCCCCGGTGCTCGCGCTGCCGGCCATCACCCTGGTGGGCCTGCCGACCTGGCGCAAGGGTTGG
GTAGCGATCCGCCACCGCACCCTCAACATCAACGCTCTGATGAGCGTGGCGGTGACCGGCGCCCTGCTGATCGGCCATTG
GTCGGAAGCCGCCATGGTGATGGTGCTGTTCACCCTGGCGGAGCATATCGAGTCACGCTCCCTGGAACGCGCCCGCCGCG
CCATTCGCGACCTGCTCGACAGCGCTCCCCGCCAGGCTCGGCGACGCGCGCCATCCGGTGAGTGGGAAAACGTCGCCGCC
GCGGACGTGGCCATCGGAGATATCGTGCGGGTGCTCCCCGGCGAGCGCCTGCCACTGGACGGCGAGGTCATGCGCGGCCA
TCCCAGCCTGGACGAGTCGCCAATCACCGGCGAAAGCCTCCCCGTCGACAAGGCTCCCGGCGACAGCGTCTTCGCCGGTG
CCATCAACCACGATGGCGACTTCGACATCCGCACCACCCGGGTGGCCAGCGACACCACCCTGGCGCGCATCATTCATGCC
GTCGAGCAGGCTCAGGCCAGCCAGGCCCCCACCCAGCGATTCATCGACCGCTTCGCCGCCGTCTACACACCCGTGGTTTT
TGCCCTGGCGGTGCTCACGGCCCTGGCCTGGCCCTGGATCGCCGGCGGTGCCTGGCTGGACGGCATCTACCGCGCCCTGG
TGCTGCTGGTGATCGCCTGCCCCTGTGCGCTGGTCATCTCCACCCCGGTGACCATCGTCAGCGGCCTTTCCGCCGCCGCC
CGGGCCGGCATCCTGATCAAGGGCGGCCGCTTTCTGGAACAGGGCAGGCGCCTGAGCTGGCTGGCACTGGACAAGACCGG
CACCCTGACCCGGGGCGAGCCGACACTGGAACACTGGGAGCCCCTCGACGAGCCCTCGGATGCCAGCAGTCGCGAGGCCC
TGGCGCGACAGGCCACCCTGCTCGCCGGGCGCTCGACGCATCCCGTATCCGCCGCCATTCATCGTGCCCTCGCACCGAAT
GCGGATGATGGCAGCGTGGATGATTTCCGCGAACTCCCCGGCCAGGGCGTCGAGGGTCGAGTCGACGGCCAGCCGCTATG
GCTCGGCAACCGCCGGCTGGCCGAAGCTCGGGGCCTGATCGACGCGACGCTTGCCGAACGCATCGAGACCCTGGAACGTC
GCGGCGCCAGCGTCGTGGCACTGGGCTCAAGCGAGCGGGTCCTGGCGCTGTTCGCCGTGCGCGACCCGCTCAAGCCCACC
AGCCTGGCGGCTATCGAGGCGCTGCATGGCCTGGGCGTGAAGACCCTGATGCTCTCCGGCGACAACCGGCACGCGGTGAG
CGCCATCGCCACGGAAGCCGGCATCGACAGCGCCCGGGGCGAACTGCTGCCCGAGGACAAGCTCGCCATCATCGAGGAAC
ACGGCCATCGCGGTGTGATCGGCATGGTCGGCGACGGCATCAACGATGCACCGGCGCTGGCCCGTGCCGATATCGGCTTC
TCCATGGGCGCGGCCGGCAGTGACGTGGCCATCGAGACCGCCGATGTGGCGCTGATGGACGACGACCTAGGCAAGCTGCC
GACCTTCCTGCGCCTGTCCCGCGCCACCTACGCCGTGCTGGTCCAGAACATCGTGCTGGCGCTCGGCATCAAGGCGGTCT
TCATGGTGCTGGCCTTCACCGGTCAGGCAACCCTGTGGATGGCGGTATTCGCCGATCTGGGGGCCAGCCTGCTGGTCATC
GGCAATGGATTGCGCCTGCTGCGCAGCCGGCTTGCCTGA

Protein sequence :
MSDAHEHGCCGGHHTEPREAVAAPADSETLRLRIQEMDCPTEEALLRKALTSAPGVAALEFDLMARILSIHHHDADTEAL
QARVRDLGMTPRPLDTDDDPSDEPPASDDTPWGRLILAALLALAAEIVGWTPWPWTDWLAPVLALPAITLVGLPTWRKGW
VAIRHRTLNINALMSVAVTGALLIGHWSEAAMVMVLFTLAEHIESRSLERARRAIRDLLDSAPRQARRRAPSGEWENVAA
ADVAIGDIVRVLPGERLPLDGEVMRGHPSLDESPITGESLPVDKAPGDSVFAGAINHDGDFDIRTTRVASDTTLARIIHA
VEQAQASQAPTQRFIDRFAAVYTPVVFALAVLTALAWPWIAGGAWLDGIYRALVLLVIACPCALVISTPVTIVSGLSAAA
RAGILIKGGRFLEQGRRLSWLALDKTGTLTRGEPTLEHWEPLDEPSDASSREALARQATLLAGRSTHPVSAAIHRALAPN
ADDGSVDDFRELPGQGVEGRVDGQPLWLGNRRLAEARGLIDATLAERIETLERRGASVVALGSSERVLALFAVRDPLKPT
SLAAIEALHGLGVKTLMLSGDNRHAVSAIATEAGIDSARGELLPEDKLAIIEEHGHRGVIGMVGDGINDAPALARADIGF
SMGAAGSDVAIETADVALMDDDLGKLPTFLRLSRATYAVLVQNIVLALGIKAVFMVLAFTGQATLWMAVFADLGASLLVI
GNGLRLLRSRLA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ORF C97 AAN62190.1 putative metal-transporting P-type ATPase Not tested PAGI-2(C) Protein 6e-164 57

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
cadA YP_003896610.1 membrane transport ATPase BAC0298 Protein 9e-165 59
cadA YP_003896610.1 membrane transport ATPase BAC0461 Protein 3e-79 42