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Name : topB (HELO_4040) Accession : YP_003899109.1 Strain : Halomonas elongata DSM 2581 Genome accession: NC_014532 Putative virulence/resistance : Unknown Product : DNA topoisomerase III Function : - COG functional category : L : Replication, recombination and repair COG ID : COG0550 EC number : 5.99.1.2 Position : 3567334 - 3569355 bp Length : 2022 bp Strand : + Note : High confidence in function and specificity DNA sequence : ATGTCCCGTCTCTTTCTTTGCGAGAAGCCCACTCAGGCCCGTGACATCGCCAAGGTCCTGGGGGCATCTGAGAAGGGTAA CGGTTGCCTCAAAGGCCGGGGCATCACCGTGACCTGGGGCTTCGGCCATCTCCTCGAGCAAGCCAATCCGGAAGCCTACG ATCCGGCACTCAAGCGCTGGTCGATGGAGTCCCTGCCCATCCTGCCGACCCAGTGGAAGCTCGAGGTCAAACCCTCGGCG AAGAAGCAGTTCACTGTCGTCAAGAAACTCCTGAGCTCGGCCAGTGAGGTGGTCATTGCCACCGACGCCGACCGTGAGGG CGAGATGATCGCCCGCGAGATCCTCGAGGCGTGTCAATTCTCAGGGGGCGTGTCCCGGCTCTGGCTGCCGGCTCTGGACG AGGCCAGCATCCGCAAGGCGCTCGGTGACATCCGGCCGGGCGAGTCCACGCGCCTGCTCTATCACGCGGCCCTGGGCCGG TCGCGCGCGGACTGGCTGGTGGGCATGAACCTGACGCGGGCATTTACCATGCGGGCCAAGCAACTGGGGTATGATCTGTT GCTGTCGGTGGGGCGTGTCCAAACACCCGTACTCAAGCTGGTCGTCGATCGCGATCGCGAGATTGCCAACTTCGTGCCCA AACCGTTCTGGGAGGTGGTCGCTGTCTTCCAGGCCGAGGGGGGGACCTTCCAGGCCAAGTGGCAGCCCGCCGATGACGAT GTTCTGGATGAGTCAGGACGGTGTATCAACCAGTCGGCGGCTCAGGCTGTCGTGGCACGTTGCCAGGGCCTGCCCGGCCA GGTCACGACGCTTGAGACGACGCGCAAGCGAGAAGCGCCTCCCTTGGCCATGGATCTGGGGACGCTGCAGCAAACCTGCT CCAAGCGTTGGGGGTATGGGGCTCAGCAGGTCCTGGATATTGCGCAAGCCCTCTACGAGACGCACAAGGCCACGACCTAC CCGCGGACGGATTGCCGTTACCTCCCGCTGTCCCAGTTGGACGACGCCCAGCAGGTCGTGACGGCACTCCTGACATCGGA TGGTGAGCTCGCCCCGGTCGTGCAGTCCCTGGATCTCACGCGCAAGAGCCGCGTGTGGAACGACAGCAAGATCACCGCCC ACCACGGCATCATTCCCACCACCTCGCCGTGCGACACCAGCAAGATGAGTGAGGCAGAATGGAATGTCTATGACCTGGTC CGGCGGCATTACTTGGCACAGTTCCTGCCGCCCCATGAGTACGATCACACCGACGTCGCGCTCGAGGTCGCTGGGGAACG CTTCGCCACCACCGGACGGCAGGTGCAGGTTGAGGGCTGGAAGGTGCTGTTTCGCAACGTCCAGCAGGATGATGCGGCGG GTGATGAGGCGACAGCGAAGACAAGCTCCCAGGCGCTACCGCCGTTGCAGGCGCATGCCAACGTACCGCAGTCCTCACTC GATCTGGTCAGCAAGACCACCACACCGCCCAAGCCTTTTGCGGAAGGCACTCTGATCGGTGCCATGAAGAACGCGGCGCG TTTCGAACCCAATCCCAAGCTCAAGGCGCGGCTCAAGGAATCCGCCGGGATCGGCACGGAGGCAACGCGCGCTGGCATCA TCGAGACGCTGCTCAAACGTAAGTTCCTGACAAAGAAGGGACGTGCGATTGTTGCCACCGCGACAGGCCGGCAGCTTATC GATGCGCTGCCTGAGGTGGTGACCAATCCCGGGATGACGGCGCTCTGGGAACAGGCCCTGGACAGCGTGGCGGCCGGCGA GCTCTCCCTCGAGGACTTCATGGCGAAGCAGCAGACCCTGGTCGAACGGCTCATCGAGCAGGCCAAGTCGGCCACCATCA ACCTTCCCCAAGAACCTGCCAAGTCCAAGGCCTGCCCGGAGTGTGGGGCCCCGATGAAGAAGCGTAAGAACGATTATGGG TCCTTCTGGGGATGCACCAAGTACCCGGACTGTAAAGGCATGGTGAAGATCGGTAGTGGCAAGAAACGCCAGGGGAAGGG ACGCAAGGCGTCTAACGGATGA Protein sequence : MSRLFLCEKPTQARDIAKVLGASEKGNGCLKGRGITVTWGFGHLLEQANPEAYDPALKRWSMESLPILPTQWKLEVKPSA KKQFTVVKKLLSSASEVVIATDADREGEMIAREILEACQFSGGVSRLWLPALDEASIRKALGDIRPGESTRLLYHAALGR SRADWLVGMNLTRAFTMRAKQLGYDLLLSVGRVQTPVLKLVVDRDREIANFVPKPFWEVVAVFQAEGGTFQAKWQPADDD VLDESGRCINQSAAQAVVARCQGLPGQVTTLETTRKREAPPLAMDLGTLQQTCSKRWGYGAQQVLDIAQALYETHKATTY PRTDCRYLPLSQLDDAQQVVTALLTSDGELAPVVQSLDLTRKSRVWNDSKITAHHGIIPTTSPCDTSKMSEAEWNVYDLV RRHYLAQFLPPHEYDHTDVALEVAGERFATTGRQVQVEGWKVLFRNVQQDDAAGDEATAKTSSQALPPLQAHANVPQSSL DLVSKTTTPPKPFAEGTLIGAMKNAARFEPNPKLKARLKESAGIGTEATRAGIIETLLKRKFLTKKGRAIVATATGRQLI DALPEVVTNPGMTALWEQALDSVAAGELSLEDFMAKQQTLVERLIEQAKSATINLPQEPAKSKACPECGAPMKKRKNDYG SFWGCTKYPDCKGMVKIGSGKKRQGKGRKASNG |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| topB | NP_458624.1 | topoisomerase B | Not tested | SPI-7 | Protein | 4e-168 | 54 |
| topB | NP_807836.1 | DNA topoisomerase III | Not tested | SPI-7 | Protein | 4e-168 | 54 |
| topB | AAF14809.1 | topoisomerase B | Not tested | SPI-7 | Protein | 3e-168 | 54 |
| topB | AAN62194.1 | putative DNA topoisomerase III | Not tested | PAGI-2(C) | Protein | 6e-178 | 53 |
| PMI2630 | YP_002152332.1 | DNA topoisomerase III | Not tested | Not named | Protein | 1e-169 | 53 |
| pph56 | CAI36097.1 | Topoisomerase IA | Not tested | PPHGI-1 | Protein | 1e-169 | 52 |
| topB | AAN62317.1 | putative DNA topoisomerase III | Not tested | PAGI-3(SG) | Protein | 1e-165 | 52 |
| topB1 | YP_005176228.1 | DNA topoisomerase III | Not tested | ICEPmu1 | Protein | 3e-161 | 51 |
| topB | AAW83109.1 | TopB | Not tested | GGI | Protein | 7e-128 | 41 |
