Gene Information

Name : entE (HELO_2836)
Accession : YP_003897905.1
Strain : Halomonas elongata DSM 2581
Genome accession: NC_014532
Putative virulence/resistance : Virulence
Product : enterobactin synthase subunit E
Function : -
COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism
COG ID : COG1021
EC number : 2.7.7.58
Position : 2142661 - 2144286 bp
Length : 1626 bp
Strand : +
Note : acetyl-coenzyme A synthetase - Parvibaculum lavamentivorans (strain DS-1 / DSM 13023 / NCIMB 13966),InterPro: AMP-dependent synthetase and ligase, High confidence in function and specificity

DNA sequence : 
ATGACGCTGCCCTTCACGCCCTGGCCCGACGAGATGGCCCGACACTATCGCCAGCAGGGCTACTGGATCGACGCCCCCTT
GACCCGTGGTGTGGCATACCAGGCACACGAACGCCCCGATGCCATCGCACTGATCTGTGGCGAGCGCCAGTTGAGCTATG
CCGAACTCGATCGGCGTGCCGCCTGCCTGGCGGCCAATCTCACCGCCCGAGGACTGGGCAAGGGAGATACGGCTCTGGTC
CAGTTGCCCAATGTCGCCGAGTTCTACCTGGTATTCCTGGCACTGCTCAAGGCCGGTATCGCCCCGGTCAATGCACTCTT
CAGCCATCGCCAACTGGAGTTGAGCGCCTACGCCCGCCAGGTGCAACCGCGCCTGGTCGTCGCCGCCCGTCAGCATGAAC
TGTTTGCCAATGACGACTTCCTGAGTGAGCTGCATCGGCTGTCCCCCCACCTCTCTGCCACCCTGCTGCTGGGAGCCTCC
GACCGCGAGACGAGTCTCGAACACTGGCTGGAAGCCCCTTCCGAGACGGGCTGGCAGGAAAGCCACACGGCTCCCGACGA
GGTTGCCTTCTTCCAGCTGTCCGGCGGCAGTACCGGCACACCCAAGCTGATCCCCCGGACACATAACGATTACGACTACA
GCGTTCGTGCAAGCGCCGACATTTGTGGTCTCTCCACCGAAACGCGATTTCTCTGCGCCTTGCCCGCGGGCCACAACTTT
CCCATGAGCTCTCCAGGGGCTCTCGGCGTCTTCCATGCAGGAGGTTGCGTGGTCATGGCTCCCAACCCTGAACCCCTCGG
TTGCTTCGAGCTGATCGAACGCCATGCCGTCGACATGGTGGCCCTGGTCCCTCCAGCCGTAGCGCTCTGGCTGCAGGCAG
CTCCCATGCATGCCAAGGCGTTGCGCTCGCTACGGCTGCTGCAGGTCGGTGGTGCCAGCTTTGCCGAGGCCACGGCCCGG
CGTGTTCCCGAGGTGCTGGGCTGTCGCCTGCAGCAGGTCTTCGGTATGGCCGAGGGCCTCGTCAACTACACCCGTCTGGA
TGATGACGATGACCTCGTTTTCACCACCCAGGGGCGACCGATCAGTCCCGCTGACGAAGTCCGGGTAGTCGACGAACAGG
GCGTCGAGGTGGACGACGGTGAGACCGGCATGCTCGCGGTACGCGGTCCCTATACCTTCCGCGGCTATTACAACAGTCCC
GAGCACAATGCCCAGGTATTCGACGCCGATGGCTTTTACTACTCGGGTGACCTGGTACAGCGCATGCCAGGGGGGTACCT
GCGCGTGGTTGGACGCATCAAGGATCAGATCAACCGGGGCGGCGAGAAGATTGCCGCCGAGGAGATCGAAAACCTGTTGC
TGCGGCATTCCGACATCACCCATGCGGCCCTGGTTGCCATGCAGGATCCCCTGATGGGGGAAAAGAGCTGCGCCTTCCTC
GTCGGCTCTGCCGAGCTGCGTCCTCCAGCTCTGCGTCAGTACCTGCGTGCCCAGGGAGTGGCCGAATACAAGCTGCCTGA
CCGGTTCCGCTTCCTCGATGCCCTGCCCGTCACGGCCATCGGCAAGATCGACAAGCAGCAGTTGCGCAAGCAACTGGCAT
CCACCACCACTTCACCCTCGCATTGA

Protein sequence : 
MTLPFTPWPDEMARHYRQQGYWIDAPLTRGVAYQAHERPDAIALICGERQLSYAELDRRAACLAANLTARGLGKGDTALV
QLPNVAEFYLVFLALLKAGIAPVNALFSHRQLELSAYARQVQPRLVVAARQHELFANDDFLSELHRLSPHLSATLLLGAS
DRETSLEHWLEAPSETGWQESHTAPDEVAFFQLSGGSTGTPKLIPRTHNDYDYSVRASADICGLSTETRFLCALPAGHNF
PMSSPGALGVFHAGGCVVMAPNPEPLGCFELIERHAVDMVALVPPAVALWLQAAPMHAKALRSLRLLQVGGASFAEATAR
RVPEVLGCRLQQVFGMAEGLVNYTRLDDDDDLVFTTQGRPISPADEVRVVDEQGVEVDDGETGMLAVRGPYTFRGYYNSP
EHNAQVFDADGFYYSGDLVQRMPGGYLRVVGRIKDQINRGGEKIAAEEIENLLLRHSDITHAALVAMQDPLMGEKSCAFL
VGSAELRPPALRQYLRAQGVAEYKLPDRFRFLDALPVTAIGKIDKQQLRKQLASTTTSPSH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 6e-80 43
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 5e-80 43
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 9e-79 43
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 9e-79 43
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 9e-79 43
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 9e-79 43
ybtE CAA21394.1 - Virulence HPI Protein 9e-79 43
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 7e-79 43
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 1e-78 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
entE YP_003897905.1 enterobactin synthase subunit E VFG0932 Protein 3e-143 59
entE YP_003897905.1 enterobactin synthase subunit E VFG0168 Protein 4e-102 48
entE YP_003897905.1 enterobactin synthase subunit E VFG1817 Protein 2e-84 44