Gene Information

Name : lipA (HELO_2411)
Accession : YP_003897480.1
Strain : Halomonas elongata DSM 2581
Genome accession: NC_014532
Putative virulence/resistance : Virulence
Product : capsule polysaccharide modification protein
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG3563
EC number : -
Position : 1633621 - 1635837 bp
Length : 2217 bp
Strand : -
Note : capsule polysaccharide modification protein lipA -Neisseria meningitidis serogroup B,InterPro: capsule polysaccharide biosynthesis, High confidence in function and specificity

DNA sequence :
ATGCAATATTCATGGCAAATGGCATTCTCGGCCCCGGTCAGCCGGACCGCGACGAAGATTGCCGGCCGGGAGCCACAAGC
GATAGGGAGATTGCCCACTCCAGGCAGCGAGATCGATCACGGTGCAGCGGATGCACAACGCGAAAAGGTCAAGCATCGAA
TAACGCCCAAGCTACAAAGGATTGTCTTTTTGGCCACGACAGCCTCAGGAACCCTCGCCGTCGCGACCCGGCGCATGCTC
GCCCTGCCCACGCTGCGCGCCTGTCTGCCCGAGTTCCAACGGCTCTGTCATCTCGGTTCTCCACGCGCGCGTCATGCCGG
CGCCGTGGCCGGATGGGGCCTCAAGCCCAGCACACGCAAGGCCCGCGAGCATGCCGATCGCCATCGGCTGCCCTATATCG
CCATCGAAGATGGCTTTTTGCGCTCATGGGGGCTTGGCGTGGAGGGGCACCCGCCCCATAGCCTCGTCGTCGACCCGCTG
GGCATCTATTACGACGCCAGCCGGCCCTCGGCACTGGAAAACCTGATCCTGGCCGCCGAGCACACGTCCGAGGCGGAGCT
CGCGCGTGCCAGAAGCGGCATGCAACAGCTGCGCGAACTGCGGCTCTCCAAGTACAACCATGCTCCGGATCGCCCGCTGT
TCGACGACGACCGGCCGCGCGTGCTGGTCGTCGACCAGACTGCCGGCGATGCCTCGATCCCCGGCGGCCTGGCCGAAGCC
GACGACTTCCAGCGGATGCTGGAGAGCGCCCGAGCCGAGCACCCCGAGTCGGAGATCCTGGTCAAGGTCCATCCCGACGT
CATCGCCGGCAAGAAAGAGGGGCATCTCCTGGCGGCCGGCCAGCTCCCCGGCTGCCGCCTGATCGGCGAGACCCTGAGCC
CCTGGTCGCTGCTCGATGCGGTGCATTGCGTGCATGTGGTCAGCAGCCAGTTGGGCTTCGAAGCCCTGCTGGCCGACAAG
CGCGTCGTCTGCCACGGCGTGCCCTTCTATGCCGGCTGGGGGCTTACCGACGACCGCCGGCACTGCCCGCGGCGCGGCGT
CCCCCGCTCGCTGGCACAGGTCTTTGCGGCGGCCTATTTCGGCTATGCCCGCTACGCCAACCCCTACACCGGCCAGGCCG
GCGACTTCGAGCAGACCCTGGAGCTGATCGGCGACCAGACTCGCCAGCAGCGCCGTCTGGCGGGGCGCTGGGTCACCTAC
GGGCTGTCGTCATGGAAGCGCGGTTTCGTCGGCGACTTTCTGGGCGATGGCACCGCCATTCGTCACCTGCGCCATAACAA
GCCCCCGGAAGGCGCCGAACGCGGCGAGCGCCTGCTGTGCTGGGCATCGCAACTGGACAGCGCCGCCGAGCAGCGGTGTC
GCGAGCGGGACCATGTCCTATGGCGCATGGAGGATGGCTTTCTGCGCTCCATCGGCCTGGGCGTCGACCTGGCCCGCCCG
CTCTCCCTGGTCGTCGATTCACTCGGCATCCATTACGACGCCAACCGCGAAAGCGAACTGGAACGCACCCTCAACGAGGC
CAGCTTCCCGCCCGCTCTATTGCAGCGTGCCGCCCGACTGCGCGAGCGGCTGGTCGCGCTGCGACTCTCCAAGTACAACG
TCCCCGGTGCACGCCGCCTCCAGCGCCCCGAGGGTGGTCGCCTGCTACTGGTACCCGGCCAGGTGGAAACCGACGCCTCC
ATAGCCCACGGCACCTTCGACATTCGCACCAACGGCGATCTGCTTGCCGCCGTGCGCCAGGCCAATCCCGAGGCCCGCAT
CCTCTACAAGCCGCATCCCGACGTGACGACTGGTGCCCGGGTCGGCGCCCTGAGCCCGGGCGACGAACGGCTCTACGACC
TCGAGGTCGGCGACGTCGATATCGTCGATTTGCTGGACATGGTCGACGAGGTCCATACCATGTGCTCCTTGGCGGGATTC
GAGGCATTGCTCCGGGGACGTCGTGTCGTCACCTACGGCATGCCGTTCTATGCGGGCTGGGGGCTGACCGAGGATCGTCA
TGCCTGCCCGAGACGTCGCCGGTCTCTCGAACTGGACGCCCTGGTCGCGGCCACCCTGATCCTCTACCCGTTGTATGTCG
ATCCGGGCAGTCGACGACTCTGCAACGCCGAAACCGTCGTGGCCCTGCTGGAACAGCGCCGAGCCGACCATCATCAACCC
GCGTGGCGAACGCACCTGTATCGCTGGTATCGCAATATCTTCATCGGAAAGCATTAA

Protein sequence :
MQYSWQMAFSAPVSRTATKIAGREPQAIGRLPTPGSEIDHGAADAQREKVKHRITPKLQRIVFLATTASGTLAVATRRML
ALPTLRACLPEFQRLCHLGSPRARHAGAVAGWGLKPSTRKAREHADRHRLPYIAIEDGFLRSWGLGVEGHPPHSLVVDPL
GIYYDASRPSALENLILAAEHTSEAELARARSGMQQLRELRLSKYNHAPDRPLFDDDRPRVLVVDQTAGDASIPGGLAEA
DDFQRMLESARAEHPESEILVKVHPDVIAGKKEGHLLAAGQLPGCRLIGETLSPWSLLDAVHCVHVVSSQLGFEALLADK
RVVCHGVPFYAGWGLTDDRRHCPRRGVPRSLAQVFAAAYFGYARYANPYTGQAGDFEQTLELIGDQTRQQRRLAGRWVTY
GLSSWKRGFVGDFLGDGTAIRHLRHNKPPEGAERGERLLCWASQLDSAAEQRCRERDHVLWRMEDGFLRSIGLGVDLARP
LSLVVDSLGIHYDANRESELERTLNEASFPPALLQRAARLRERLVALRLSKYNVPGARRLQRPEGGRLLLVPGQVETDAS
IAHGTFDIRTNGDLLAAVRQANPEARILYKPHPDVTTGARVGALSPGDERLYDLEVGDVDIVDLLDMVDEVHTMCSLAGF
EALLRGRRVVTYGMPFYAGWGLTEDRHACPRRRRSLELDALVAATLILYPLYVDPGSRRLCNAETVVALLEQRRADHHQP
AWRTHLYRWYRNIFIGKH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsC YP_854335.1 capsule polysaccharide export protein KpsC Not tested PAI I APEC-O1 Protein 3e-84 46
kpsC AAZ04470.1 capsule polysaccharide export protein Virulence PAI I APEC-O1 Protein 3e-84 46
lipA NP_273145.1 capsule polysaccharide modification protein Not tested IHT-A Protein 2e-102 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lipA YP_003897480.1 capsule polysaccharide modification protein VFG0692 Protein 5e-98 45
lipA YP_003897480.1 capsule polysaccharide modification protein VFG0259 Protein 9e-103 44
lipA YP_003897480.1 capsule polysaccharide modification protein VFG0704 Protein 5e-81 43